Article (Scientific journals)
Distribution and evolution of ferripyoverdine receptors in Pseudomonas aeruginosa.
Bodilis, Josselin; Ghysels, Bart; Osayande, Julie et al.
2009In Environmental Microbiology, 11 (8), p. 2123-35
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Keywords :
Bacterial Outer Membrane Proteins/classification/genetics/isolation & purification; Evolution, Molecular; Genes, Bacterial; Phylogeny; Polymerase Chain Reaction; Pseudomonas aeruginosa/classification/genetics
Abstract :
[en] Pseudomonas aeruginosa is a ubiquitous gram-negative bacterium, which is also able to cause severe opportunistic infections in humans. The colonization of the host is importantly affected by the production of the high-affinity iron (III) scavenging peptidic siderophore pyoverdine. The species P. aeruginosa can be divided into three subgroups ('siderovars'), each characterized by the production of a specific pyoverdine and receptor (FpvA). We used a multiplex PCR to determine the FpvA siderovar on 345 P. aeruginosa strains from environmental or clinical origin. We found about the same proportion of each type in clinical strains, while FpvA type I was slightly over-represented (49%) in environmental strains. Our multiplex PCR also detected the presence or absence of an additional receptor for type I pyoverdine (FpvB). The fpvB gene was in fact present in the vast majority of P. aeruginosa strains (93%), regardless of their siderovar or their origin. Finally, molecular analyses of fpvA and fpvB genes highlighted a complex evolutionary history, probably linked to the central role of iron acquisition in the ecology and virulence of P. aeruginosa.
Disciplines :
Microbiology
Author, co-author :
Bodilis, Josselin
Ghysels, Bart ;  Université de Liège - ULiège > Labo de Bioénergétique
Osayande, Julie
Matthijs, Sandra
Pirnay, Jean-Paul
Denayer, Sarah
De Vos, Daniel
Cornelis, Pierre
Language :
English
Title :
Distribution and evolution of ferripyoverdine receptors in Pseudomonas aeruginosa.
Publication date :
2009
Journal title :
Environmental Microbiology
ISSN :
1462-2912
eISSN :
1462-2920
Publisher :
Wiley, Oxford, United Kingdom
Volume :
11
Issue :
8
Pages :
2123-35
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 29 January 2014

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