Cost-effectiveness of denosumab in the treatment of postmenopausal osteoporotic women.

Hiligsmann, Mickaël; Boonen, Annelies; Dirksen, Carmen D.; Ben Sedrine, Wafa; REGINSTER, Jean-Yves

doi:10.1586/erp.12.76

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Article (Scientific journals)

Cost-effectiveness of denosumab in the treatment of postmenopausal osteoporotic women.

Hiligsmann, Mickaël; Boonen, Annelies; Dirksen, Carmen D. et al.

2013 • In Expert Review of Pharmacoeconomics and Outcomes Research, 13 (1), p. 19-28

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https://hdl.handle.net/2268/156126

DOI
10.1586/erp.12.76

PubMed
23402442

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Abstract :

[en] Denosumab is a novel biological agent for the treatment of osteoporosis in postmenopausal women with increased risk of fractures. With limited healthcare resources, economic evaluations are increasingly being used by decision-makers to optimize healthcare resource allocation. The cost-effectiveness of denosumab has been evaluated in various studies, and a systematic literature study was conducted up to April 2012 to identify all published research articles and research abstracts presented at various congresses. This article provides a systematic review of four articles and eight abstracts reporting on the cost-effectiveness of denosumab in the treatment of osteoporosis. In most economic evaluations, denosumab has been considered as a cost-effective treatment compared with first-line and second-line options (including generic alendronate) in the treatment of women with high risk of fractures.

Disciplines :

General & internal medicine

Author, co-author :

Hiligsmann, Mickaël ; Université de Liège - ULiège > Département des sciences de la santé publique > Département des sciences de la santé publique

Boonen, Annelies

Dirksen, Carmen D.

Ben Sedrine, Wafa ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé

REGINSTER, Jean-Yves ; Centre Hospitalier Universitaire de Liège - CHU > Médecine de l'appareil locomoteur

Language :

English

Title :

Cost-effectiveness of denosumab in the treatment of postmenopausal osteoporotic women.

Publication date :

2013

Journal title :

Expert Review of Pharmacoeconomics and Outcomes Research

ISSN :

1473-7167

eISSN :

1744-8379

Publisher :

Taylor & Francis, United Kingdom

Volume :

Issue :

Pages :

19-28

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 18 September 2013

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