[en] The aim of this study was to evaluate the performance
of the General Electric eXplore 120 micro-CT regarding image
quality and delivered dose of several protocols. Image quality
(resolution, linearity, uniformity and geometric accuracy) was
assessed using the vmCT phantom developed for the GE eXplore
Ultra, the QRM low contrast and the QRM Bar Pattern
Phantom. All dose measurements were performed using a
mobileMOSFET dose verification system and the CTDI100 and
the MSAD were determined with a custom built PMMA
phantom. Additionally, in vivo scans in sacrificed rats with
different weights were acquired to assess dose, contrast and
resolution variation due to X-ray absorption in surrounding
tissue. The spatial resolution was determined as between 95 and
138 μm with a geometric accuracy of 0.1%. The system has a
highly linear response to the iodine concentrations (0.937 to 30
mg/ml) for all protocols. The calculated CTDI100 ranged from
20.15 to 56.79 mGy and the MSAD from 27.98 to 77.45 mGy. The
results were confirmed by in vivo scans in rats with different
weights and no impact of body weight on delivered dose could be
observed. However, body weight had a slight impact on image
contrast and resolution.
Research center :
GIGA CRC (Cyclotron Research Center) In vivo Imaging-Aging & Memory - ULiège
Disciplines :
Radiology, nuclear medicine & imaging
Author, co-author :
Bretin, Florian ; Université de Liège - ULiège > Centre de recherches du cyclotron
Warnock, Geoffrey
Luxen, André ; Université de Liège - ULiège > Département de chimie (sciences) > Chimie organique de synthèse
Plenevaux, Alain ; Université de Liège - ULiège > Centre de recherches du cyclotron
Seret, Alain ; Université de Liège - ULiège > Département de physique > Imagerie médicale expérimentale
Bahri, Mohamed Ali ; Université de Liège - ULiège > Centre de recherches du cyclotron
Language :
English
Title :
Performance evaluation and X-ray dose quantification for various scanning protocols of the GE eXplore 120 micro-CT
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