Article (Scientific journals)
What is the predictive value of MRI for the occurrence of knee replacement surgery in knee osteoarthritis?
Pelletier, J.-P.; Cooper, C.; Peterfy, C. et al.
2013In Annals of the Rheumatic Diseases, 72 (10), p. 1594-1604
Peer Reviewed verified by ORBi
 

Files


Full Text
What is the predictive value of MRI for the occurrence of knee replacement surgery in knee osteoarthritis.pdf
Publisher postprint (1.18 MB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Knee Osteoarthritis; Magnetic Resonance Imaging; Outcomes research
Abstract :
[en] Knee osteoarthritis is associated with structural changes in the joint. Despite its many drawbacks, radiography is the current standard for evaluating joint structure in trials of potential disease-modifying osteoarthritis drugs. MRI is a non-invasive alternative that provides comprehensive imaging of the whole joint. Frequently used MRI measurements in knee osteoarthritis are cartilage volume and thickness; others include synovitis, synovial fluid effusions, bone marrow lesions (BML) and meniscal damage. Joint replacement is considered a clinically relevant outcome in knee osteoarthritis; however, its utility in clinical trials is limited. An alternative is virtual knee replacement on the basis of symptoms and structural damage. MRI may prove to be a good alternative to radiography in definitions of knee replacement. One of the MRI parameters that predicts knee replacement is medial compartment cartilage volume/thickness, which correlates with radiographic joint space width, is sensitive to change, and predicts outcomes in a continuous manner. Other MRI parameters include BML and meniscal lesions. MRI appears to be a viable alternative to radiography for the evaluation of structural changes in knee osteoarthritis and prediction of joint replacement.
Disciplines :
General & internal medicine
Author, co-author :
Pelletier, J.-P.
Cooper, C.
Peterfy, C.
REGINSTER, Jean-Yves  ;  Centre Hospitalier Universitaire de Liège - CHU > Médecine de l'appareil locomoteur
Brandi, M.-L.
Bruyère, Olivier  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Chapurlat, R.
Cicuttini, F.
Conaghan, P. G.
Doherty, M.
Genant, H.
Giacovelli, G.
Hochberg, M. C.
Hunter, D. J.
Kanis, J. A.
Kloppenburg, M.
Laredo, J.-D.
McAlindon, T.
Nevitt, M.
Raynauld, J.-P.
Rizzoli, R.
Zilkens, C.
Roemer, F. W.
Martel-Pelletier, J.
Guermazi, A.
More authors (15 more) Less
Language :
English
Title :
What is the predictive value of MRI for the occurrence of knee replacement surgery in knee osteoarthritis?
Publication date :
2013
Journal title :
Annals of the Rheumatic Diseases
ISSN :
0003-4967
eISSN :
1468-2060
Publisher :
BMJ Group, London, United Kingdom
Volume :
72
Issue :
10
Pages :
1594-1604
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 05 September 2013

Statistics


Number of views
53 (4 by ULiège)
Number of downloads
1 (1 by ULiège)

Scopus citations®
 
88
Scopus citations®
without self-citations
39
OpenCitations
 
82

Bibliography


Similar publications



Contact ORBi