[en] This work applies a “product-oriented engineering” approach to the development of porous scaffolds for tissue engineering. Polylactic acid scaffolds were obtained by a freeze-drying process. Their 2D/3D microstructure was characterized by X-ray microtomography and related to the operating conditions used. Two types of scaffold end-use properties were characterized in
relation to their microstructure: the mechanical and the transport properties. Scaffold young's modulus was computed from data measured on tension-compression devices. To evaluate the permeability, Darcy’s experiments were carried out. The obtained results allowed highlighting the quantitative relationships existing between elaboration conditions, microstructure and end use properties of the fabricated PLA scaffolds.
Research Center/Unit :
Center for Education and Research on Macromolecules (CERM)
Disciplines :
Materials science & engineering Engineering, computing & technology: Multidisciplinary, general & others Chemical engineering
Author, co-author :
de Bien, Charlotte ; Université de Liège - ULiège > Département de chimie appliquée > Génie chimique - Procédés et développement durable
Ounally, Thameur ; Université de Liège - ULiège > stage conv. étrangères ou CFb en sc. appl.
Collard, Valérie ; University of Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Jérôme, Christine ; University of Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Léonard, Angélique ; Université de Liège - ULiège > Département de chimie appliquée > Génie chimique - Procédés et développement durable
Toye, Dominique ; Université de Liège - ULiège > Département de chimie appliquée > Génie de la réaction et des réacteurs chimiques
Language :
English
Title :
"Product-oriented engineering" applied to the development of porous scaffolds for tissue engineering.
Publication date :
02 September 2013
Event name :
7th World Congress on Industrial Process Tomography (WCIPT7)
