Atrial Function, Left; Cardiomyopathy, Hypertrophic/complications/ultrasonography; Echocardiography/methods; Elasticity Imaging Techniques/methods; Female; Heart Atria/ultrasonography; Heart Failure/etiology/ultrasonography; Humans; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Statistics as Topic
Abstract :
[en] BACKGROUND: Hypertrophic cardiomyopathy (HCM) represents a generalized myopathic process affecting both ventricular and atrial myocardium. We aimed to assess left atrial (LA) function by two-dimensional speckle tracking echocardiography and its relation with left ventricular (LV) function and clinical status in patients with HCM. METHODS: We prospectively enrolled 37 consecutive patients with HCM and 37 normal subjects with similar age and gender distribution. Longitudinal LV strain (epsilon) and LA epsilon and strain rate (Sr) parameters (systolic, early diastolic, and late diastolic during atrial contraction) were assessed. RESULTS: Peak LAepsilon and LA Sr parameters were significantly lower in patients compared with controls (P
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