[en] The ring-opening polymerization of 1,4,8-trioxaspiro-[4,6]-9-undecanone (TOSUO) initiated by aluminum isopropoxide, Al(OiPr)3, is typically "living" and allows random and block copolyesters of predictable molecular weight and composition to be prepared. Deacetalization of the polyester chains is complete, and reduction of the accordingly formed ketone groups into hydroxyl groups as well. No chain scission is observed when these two derivatization reactions are carried out. The potential of these novel functional aliphatic polyesters has been discussed as drug colloidal vectors and macroinitiators for the synthesis of biodegradable and biocompatible comb, graft and even hyperbranched polymers.
Research Center/Unit :
Center for Education and Research on Macromolecules (CERM)
Disciplines :
Materials science & engineering Chemistry
Author, co-author :
Tian, Dong; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Dubois, Philippe ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Jérôme, Robert ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Language :
English
Title :
Ring-opening polymerization of 1,4,8-trioxaspiro-[4.6]-9-undecanone: a route to novel molecular architectures for biodegradable aliphatic polyesters
Publication date :
April 1998
Journal title :
Macromolecular Symposia
ISSN :
1022-1360
eISSN :
1521-3900
Publisher :
Wiley-V C H Verlag Gmbh, Weinheim, Germany
Volume :
130
Pages :
217-227
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
BELSPO - SPP Politique scientifique - Service Public Fédéral de Programmation Politique scientifique F.R.S.-FNRS - Fonds de la Recherche Scientifique
T. Ouhadi, C. Stevens, Ph. Teyssié, Makromol. Chem., Suppl. 1, 191 (1975)
A. Hamitou, T. Ouhadi, R. Jérôme, Ph. Teyssié, J. Polym. Sci. Polym. Chem. Ed. 15, 865 (1977)
M. Endo, T. Aida, S. Inoue, Macromolecules 20, 2982 (1987)
A. Hofman, S. Slomkowski, S. Penczek, Makromol. Chem., Rapid. Commun. 3,387 (1987)
Ph. Dubois, Ph. Degée, N. Ropson, R. Jérôme, "Macromolecular Engineering of Polylactones and Polylactides by Ring-Opening Polymerization" in : Macromolecular Design of Polymeric Materials. Ed. by K. Hatada, Marcel Dekker Inc., Chap. 41, 1994, pp. 247-272
Ph. Dubois, J. S. Zhang, R. Jérôme, Ph. Teyssié, Polymer 35, 4998 (1994)
D. Tian, Ph. Dubois, R. Jérôme, Ph. Teyssié, Macromolecules 27, 4134 (1994)
D. Tian, Ph. Dubois, Ch. Grandfils, R. Jérôme, Macromolecules 30, 406 (1997)
Ph. Dubois, C. Jacobs, R. Jérôme, Ph. Teyssié, Macromolecules 24, 2266 (1991)
A. Duda, S. Penczek, Macromol. Rapid. Commun. 16, 67 (1995)
N. Ropson, Ph. Dubois, R. Jérôme, Ph. Teyssié, Macromolecules 28, 7589 (1995)
A. Duda, S. Penczek, Macromolecules 28, 5981 (1995)
D. Tian, Ph. Dubois, R. Jérôme, accepted for communication in Macromolecules as part 22 of the series of papers "Macromolecular Engineering of Polylactones and Polylactides"
D. Tian, Ph. Dubois, R. Jérôme, Macromolecules 30, 1947 (1997)
D.H.R. Barton, P.D. Magnus, G. Smith, G. Streckert, D. Zurr, J. Chem. Soc., Perkin Trans. I. 542 (1972).
A. Duda, S. Penczek, Makromol. Chem., Macromol. Symp. 47, 127 (1991)
S. Penczek, A. Duda, T. Biela, Polym. Prepr., Am. Chem.; Soc. Div. Polym. Chem. 35, 508 (1994)
G. Pitt, Z. W. Gu, P. Ingram, R. W. Hendren, J. Polym. Sci.: Polym. Chem. 25, 955 (1987)
