Reference : Study of the Influence of Pure Ionic Liquids on the Lipase-catalyzed (Trans)esterific...
Scientific journals : Article
Physical, chemical, mathematical & earth Sciences : Chemistry
http://hdl.handle.net/2268/147089
Study of the Influence of Pure Ionic Liquids on the Lipase-catalyzed (Trans)esterification of Mannose Based on their Anion and Cation Nature
English
Galonde, Nadine mailto [Université de Liège - ULiège > Chimie et bio-industries > Chimie générale et organique >]
Nott, Katherine mailto [Université de Liège - ULiège > Chimie et bio-industries > Chimie biologique industrielle >]
Richard, Gaetan mailto [Université de Liège - ULiège > Chimie et bio-industries > Chimie biologique industrielle >]
Debuigne, Antoine mailto [Université de Liège - ULiège > Département de chimie (sciences) > Chimie des macromolécules et des matériaux organiques >]
Nicks, Francois [Université de Liège - ULiège > Chimie et bio-industries > Chimie biologique industrielle >]
Jérôme, Christine mailto [Université de Liège - ULiège > Département de chimie (sciences) > Centre d'études et de rech. sur les macromolécules (CERM) >]
Fauconnier, Marie-Laure mailto [Université de Liège - ULiège > Chimie et bio-industries > Chimie générale et organique >]
Apr-2013
Current Organic Chemistry
Bentham Science Publishers Ltd.
17
7
763-770
Yes (verified by ORBi)
International
1385-2728
Sharjah
United Arab Emirates
[en] Acylation ; biocatalysis ; carbohydrates ; green chemistry ; ionic liquids ; Novozym® 435 ; mannosyl myristate ; sugar esters
[en] A screening of nine ionic liquids (ILs) has been carried out in order to study the influence of the anion's and cation's nature and structure on the synthesis of mannosyl myristate by (trans)esterification catalyzed by Novozym® 435. The best ILs in terms of yield (η) and initial rate (v0) are those based on the TFO- anion. The 24h yield (24h-η) reached 64.9% in [Bmim][TFO] and 70.9% in [Bmpyrr][TFO] by transesterification while it reached 29.7% and 44.5% respectively in each IL by esterification. [Bmpyrr][TFO] based on the pyrrolidinium cation gave the best results although this cation has been rarely used for biocatalysis. This work has thus highlighted a cation that could be further studied in biocatalysis of glycosylated compounds. The study of the relationship between the structure of the ILs and the v0 and η for the biocatalysis of mannosyl myristate showed that the lipase effectiveness is influenced by the anions while the cations have an indirect influence on the interaction strength between Novozym® 435 and the anions.
Researchers
http://hdl.handle.net/2268/147089
also: http://hdl.handle.net/2268/164667
10.2174/1385272811317070010
http://benthamscience.com/journal/index.php?journalID=coc

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