Reference : La prescription médicamenteuse chez la personne âgée: que devons-nous savoir?
Scientific journals : Article
Human health sciences : Geriatrics
Human health sciences : Pharmacy, pharmacology & toxicology
La prescription médicamenteuse chez la personne âgée: que devons-nous savoir?
[en] Drug therapy in the elderly. What should we know?
Wotquenne, Pol mailto [Centre Hospitalier Universitaire de Liège - CHU > > Urgences >]
Petermans, Jean mailto [Centre Hospitalier Universitaire de Liège - CHU > > Gériatrie >]
Scheen, André mailto [Université de Liège - ULiège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale >]
Revue Médicale Suisse
1878-80, 1882-3
Yes (verified by ORBi)
[en] Aged ; Drug Therapy ; Humans ; Pharmaceutical Preparations/adverse effects ; Pharmacokinetics
[en] Because of the increasing longevity of the population, a growing number of very old people are exposed to medications. Drug therapy in this population is difficult because of our lack of knowledge. The number of drugs administered is generally high and the prescription is often inappropriate. Changes in body composition, malnutrition and renal failure can cause drug accumulation and toxicity. However, hepatic metabolism via cytochrome P450 does not seem to be markedly influenced by oldness. Iatrogenic pathology is frequent in the elderly and may lead to hospitalisation and reduction in quality of life. Specific education of the medical care team should be promoted in order to tackle this important problem of public health.
Researchers ; Professionals ; Students

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