[en] The risk linked to furan ingestion has been assessed in previous papers for Belgian adults and children (Scholl et al., 2012b; Scholl et al., 2012c). The present paper focuses on infants consuming only ready-to-eat baby food. As there is no Belgian baby dietary database, the furan exposure assessment was carried out by using Italian infant consumption database and Belgian contamination data. The estimated daily intake (EDI) was calculated according to a deterministic methodology. It involved 42 commercially available ready-to-eat baby food and 36 baby consumption records. The mean EDI was 1,460 ng * (kgb.w.*day)-1 which is 3.8 times higher than the 381 ng * (kgb.w.*day)-1 reported for Belgian adults, and 3.5 times higher than the 419 ng * (kgb.w. * day)-1 measured for Belgian children. To assess and characterize the risk for babies exposure the Margin of Exposure (MoE) was calculated. It highlighted that 74% of infants have a MoE below 1,000, with a minimum of 140. However, these are only preliminary results as they were calculated from a very small dataset and the infant cytochrome P450 activity is significantly different compared to the adult. Therefore, the risk linked to furan ingestion by babies should be assessed in a different manner. To this end, additional data regarding a baby diet as well as a better understanding of furan toxicity for babies are needed to characterize more accurately the risk for infants.
Research Center/Unit :
CART - Centre Interfacultaire d'Analyse des Résidus en Traces - ULiège
Disciplines :
Chemistry
Author, co-author :
Scholl, Georges ; Université de Liège - ULiège > Center for Analytical Research and Technology (CART)
Humblet, Marie-France ; Université de Liège - ULiège > Services administratifs généraux > Protection et hygiène du travail (SUPHT)
Scippo, Marie-Louise ; Université de Liège - ULiège > Département de sciences des denrées alimentaires > Analyse des denrées alimentaires
De Pauw, Edwin ; Université de Liège - ULiège > Département de chimie (sciences) > GIGA-R : Laboratoire de spectrométrie de masse (L.S.M.)
Eppe, Gauthier ; Université de Liège - ULiège > Département de chimie (sciences) > Chimie analytique inorganique
Saegerman, Claude ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Epidémiologie et analyse des risques appl. aux sc. vétér.
Language :
English
Title :
Preliminary assessment of the risk linked to furan ingestion by babies consuming only ready-to-eat food
Publication date :
2013
Journal title :
Food Additives and Contaminants. Part A. Chemistry, Analysis, Control, Exposure and Risk Assessment
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