Abstract :
[en] Platelet-rich plasma (PRP) may represent a new therapeutic option for chronic tendinopathies. Platelets release various cytokines and growth factors which promote angiogenesis, tissue remodeling, and wound healing. We made an exhaustive review of the use of PRP in chronic tendinopathies: epicondylitis, rotator cuff, patellar and calcaneal tendinopathies, and plantar fasciitis.
Medline, Embase and Google Scholar were used (until July 31, 2012). Clinical studies about PRP and tendinopathies (in English and French language peer-reviewed journals) were included. Articles with a high level of evidence were considered preferentially.
Despite the proven efficacy of PRP on tissue regeneration in experimental studies, there is currently scanty tangible clinical evidence with respect to chronic tendon disorders. The few studies that have been performed appear unlikely to be comparable.
Randomized controlled studies with appropriate placebo groups are needed to determine the real effectiveness of PRP for treating chronic musculoskeletal injuries.
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