[en] The development of controlled drug delivery systems is today a topic of an intense research activity. In this field, biocompatible and (bio)degradable polymers are particularly studied. The production of nanosized particles (polymer micelles, nanoparticles,...) generally requires the elaboration of functional amphiphilic copolymers able to stabilize efficiently these colloidal dispersions. Various strategies to synthesize such copolymers keeping their (bio)degradability are described here. The complexity of these amphiphilic materials will be gradually increased in parallel to the improvement of the nanocarriers properties.
Research Center/Unit :
Center for Education and Research on Macromolecules (CERM)
Disciplines :
Materials science & engineering Chemistry
Author, co-author :
Jérôme, Christine ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Van Butsele, Kathy ; University of Liège (Ug) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Language :
French
Title :
Amphiphilic and biodegradable copolymers for applications in vectorisation
Alternative titles :
[fr] Copolymères amphiphiles biodégradables pour la vectorisation
Publication date :
March 2007
Journal title :
Chimie Nouvelle
ISSN :
0771-730X
Publisher :
Société Royale de Chimie (SRC)) de Belgique, Bruxelles, Belgium
BELSPO - Service Public Fédéral de Programmation Politique scientifique F.R.S.-FNRS - Fonds de la Recherche Scientifique FRIA - Fonds pour la Formation à la Recherche dans l'Industrie et dans l'Agriculture Walloon region