[en] In the past years, mass univariate statistical analyses of neuroimaging data have been complemented by the use of multivariate pattern analyses, especially based on machine learning models. While these allow an increased sensitivity for the detection of spatially distributed effects compared to univariate techniques, they lack an established and accessible software framework. The goal of this work was to build a toolbox comprising all the necessary functionalities for multivariate analyses of neuroimaging data, based on machine learning models. The “Pattern Recognition for Neuroimaging Toolbox” (PRoNTo) is open-source, cross-platform, MATLAB-based and SPM compatible, therefore being suitable for both cognitive and clinical neuroscience research. In addition, it is designed to facilitate novel contributions from developers, aiming to improve the interaction between the neuroimaging and machine learning communities. Here, we introduce PRoNTo by presenting examples of possible research questions that can be addressed with the machine learning framework implemented in PRoNTo, and cannot be easily investigated with mass univariate statistical analysis.
Research Center/Unit :
Computer Science Department, University College London Institute of Psychology, King's College, London Wellcome Trust, London GIGA CRC (Cyclotron Research Center) In vivo Imaging-Aging & Memory - ULiège Ecole Polytechnique Fédérale de Lausanne
Disciplines :
Engineering, computing & technology: Multidisciplinary, general & others Human health sciences: Multidisciplinary, general & others
Author, co-author :
Schrouff, Jessica ; Université de Liège - ULiège > Centre de recherches du cyclotron
Rosa, Maria Joao
Rondina, Jane
Marquand, Andre
Chu, Carlton
Ashburner, John
Phillips, Christophe ; Université de Liège - ULiège > GIGA > GIGA CRC In vivo Imaging - Neuroimaging, data acquisition and processing ; Université de Liège - ULiège > Centre de recherches du cyclotron
Richiardi, Jonas
Mourão-Miranda, Janaina
Language :
English
Title :
PRoNTo: Pattern Recognition for Neuroimaging Toolbox
F.R.S.-FNRS - Fonds de la Recherche Scientifique FRIA - Fonds pour la Formation à la Recherche dans l'Industrie et dans l'Agriculture UCL - University College London Wellcome Trust FCT - Fundação para a Ciência e a Tecnologia SNSF - Swiss National Science Foundation
Funding text :
Swiss National Science Foundation (PP00P2-123438) and Center for Biomedical Imaging (CIBM) of the EPFL and Universities and Hospitals of Lausanne and Geneva; The King’s College London Centre of Excellence in Medical Engineering, funded by the Wellcome Trust and EPSRC under grant no. WT088641/Z/09/Z
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