Article (Scientific journals)
Study of hypotonic polyuria after trans-sphenoidal pituitary adenomectomy.
HANS, Pol; Stevenaert, Achille; Albert, Adelin
1986In Intensive Care Medicine, 12 (2), p. 95-9
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Keywords :
Adenoma/surgery; Adolescent; Adult; Aged; Diabetes Insipidus/etiology; Diuresis; Female; Humans; Male; Middle Aged; Osmolar Concentration; Pituitary Neoplasms/surgery; Polyuria/etiology; Postoperative Complications/etiology; Postoperative Period; Specific Gravity; Sphenoid Bone
Abstract :
[en] We have studied the postoperative diuresis patterns in 116 patients following the removal of a pituitary adenoma using the trans-sphenoidal approach. We observed a normal diuresis (ND) in 55 patients and a hypotonic polyuria (HP) in 61 patients, consisting of water elimination (WE = 45 cases) and transient diabetes insipidus (DI = 16 cases). We investigated the problem of predicting these patterns from eight pre-operative factors by applying stepwise logistic discriminant analysis. We demonstrated that DI was significantly associated with a posterior localization of the adenoma in the pituitary gland and that WE was more frequently observed in cases of suprasellar expansion, in young patients, and in prolactin secreting tumors. Finally, we discuss the pathogenic role of these factors in the occurrence of HP, taking into account inhibition of vasopressin secretion and possible fluid overload.
Disciplines :
General & internal medicine
Author, co-author :
HANS, Pol ;  Centre Hospitalier Universitaire de Liège - CHU > Anesthésie et réanimation
Stevenaert, Achille ;  Université de Liège - ULiège > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine)
Albert, Adelin  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Informatique médicale et biostatistique
Language :
English
Title :
Study of hypotonic polyuria after trans-sphenoidal pituitary adenomectomy.
Publication date :
1986
Journal title :
Intensive Care Medicine
ISSN :
0342-4642
eISSN :
1432-1238
Publisher :
Springer Verlag, New York, United States - New York
Volume :
12
Issue :
2
Pages :
95-9
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 21 January 2013

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