[en] We report the findings and outputs of an international expert opinion process to develop a definition of early Crohn's disease (CD) that could be used in future disease-modification trials. Nineteen experts on inflammatory bowel diseases held an international expert opinion meeting to discuss and agree on a definition for early CD to be used in disease-modification trials. The process included literature searches for the relevant basic-science and clinical evidence. A published preliminary definition of early CD was used as the basis for development of a proposed definition that was discussed at the expert opinion meeting. The participants then derived a final definition, based on best current knowledge, that it is hoped will be of practical use in disease-modification trials in CD.
Disciplines :
Gastroenterology & hepatology
Author, co-author :
Peyrin-Biroulet, Laurent
Billioud, Vincent
D'Haens, Geert
Panaccione, Remo
Feagan, Brian
Panes, Julian
Danese, Silvio
Schreiber, Stefan
Ogata, Haruhiko
Hibi, Toshifumi
Higgins, Peter D. R.
Beaugerie, Laurent
Chowers, Yehuda
LOUIS, Edouard ; Centre Hospitalier Universitaire de Liège - CHU > Gastro-Entérologie-Hépatologie
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