Reference : Atteinte cerebrale au cours d'une maladie de Wegener.
Scientific journals : Article
Human health sciences : General & internal medicine
Atteinte cerebrale au cours d'une maladie de Wegener.
[en] Central nervous system involvement in Wegener's granulomatosis
JOURET, François mailto [Centre Hospitalier Universitaire de Liège - CHU > > Néphrologie >]
Noirhomme, S. [> >]
Grandin, C. [> >]
Lonneux, M. [> >]
Godfraind, C. [> >]
Lambert, Michel []
Lefebvre, C. [> >]
Revue de Médecine Interne
Yes (verified by ORBi)
[en] Biopsy ; Brain/pathology/radiography ; Cerebrovascular Disorders/pathology/radiography ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Paranasal Sinuses/pathology/radiography ; Tomography, X-Ray Computed ; Wegener Granulomatosis/complications/radiography
[en] INTRODUCTION: Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis associated with c-ANCA antibodies. The involvement of the central nervous system in WG is uncommon and usually caused by in situ vasculitis, intracranial granuloma formation or contiguous invasion from extracranial sites. CASE REPORT: Here, we report on a tumour-like expansion of a severe nasosinusal WG into the brain, which was confirmed by brain biopsy examination. CONCLUSION: The positivity of positron emission tomography in our observation supports the potential role of such functional imaging in the staging, as well as in the follow-up of WG.

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