[en] This review describes different strategies of surface elaboration for a better control of biomolecule adsorption. After a brief description of the fundamental interactions between surfaces and biomolecules, various routes of surface elaboration are presented dealing with the attachment of functional groups mostly thanks to plasma techniques, with the grafting to and from methods, and with the adsorption of surfactants. The grafting of stimuli-responsive polymers is also pointed out. Then, the discussion is focused on the protein adsorption phenomena showing how their interactions with solid surfaces are complex. The adsorption mechanism is proved to be dependent on the solid surface physicochemical properties as well as on the surface and conformation properties of the proteins. Different behaviors are also reported for complex multiple protein solutions.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Poncin-Epaillard, Fabienne
Vrlinic, Tjasa
Mozetic, Miran
Coudreuse, Arnaud
Legeay
Elmoualij, Benaïssa ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie
Zorzi, Willy ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie
Language :
English
Title :
Surface Treatment of Polymeric Materials Controlling the Adhesion of Biomolecules
Publication date :
17 August 2012
Journal title :
Journal of Functional Biomaterials
eISSN :
2079-4983
Publisher :
Molecular Diversity Preservation International (MDPI), Basel, Switzerland