Dermal Dendrocytes and Photochemotherapy

[en] We studied the fate of dermal dendrocytes in patients treated with psoralens and ultraviolet light by combining immunohistochemistry and computerized image analysis. Factor-XIIIa-positive dermal dendrocytes were found to be altered in these patients. When compared with controls, dermal dendrocytes were often increased in number and had an uneven size and tissue distribution. Their cytoplasm was occasionally fragmented. These changes were more pronounced when early photosclerosis was present. The alterations described probably reflect vascular changes, and may be responsible for immunomodulating actions and disorder of the connective tissue structure induced by ultraviolet light.

Disciplines :

Dermatology

Author, co-author :

Pierard, Gérald ; Université de Liège - ULiège > Département des sciences cliniques > Dermatopathologie

Nikkels, Arjen ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Arrese Estrada, Jorge ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques

Ben Mosbah, T.

Pierard-Franchimont, Claudine ; Université de Liège - ULiège > Département des sciences cliniques > Dermatopathologie

Language :

English

Title :

Dermal Dendrocytes and Photochemotherapy

Publication date :

1991

Journal title :

Virchows Archiv. A: Pathological Anatomy and Histopathology

ISSN :

0174-7398

Publisher :

Springer, Germany

Volume :

418

Issue :

Pages :

311-314

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 12 March 2010

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Bibliography

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