[en] Fatal mural endocarditis and botryomycosis occurred concurrently in a 62-year-old women 4 months after orthotopic heart transplantation. Subsequent to mild mitral regurgitation, infection developed on a left atrial thrombus and was complicated by cerebral embolization. Simultaneously, skin nodules manifested on both forearms. Histologic examination revealed typical aspects of early evolving botryomycosis with massive infiltration of the dermis and hypodermis by necrotic granulomas framed by grains of Gram-positive coccoid forms. Bacteria were decorated by a nonspecific polyclonal antibody to Mycobacterium bovis.
Disciplines :
Cardiovascular & respiratory systems Dermatology Surgery
Author, co-author :
Defraigne, Jean-Olivier ; Université de Liège - ULiège > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique
Demoulin, J. C.
Pierard, Gérald ; Université de Liège - ULiège > Département des sciences cliniques > Dermatopathologie
DETRY, Olivier ; Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
Limet, Raymond ; Université de Liège - ULiège > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique
Language :
English
Title :
Fatal Mural Endocarditis and Cutaneous Botryomycosis after Heart Transplantation
Publication date :
1997
Journal title :
American Journal of Dermatopathology
ISSN :
0193-1091
eISSN :
1533-0311
Publisher :
Lippincott Williams & Wilkins, Philadelphia, United States - Pennsylvania
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