Antibacterial polyelectrolyte micelles for coating stainless steel

[en] In this study, we report on the original synthesis and characterization of novel antimicrobial coatings for stainless steel by alternating the deposition of aqueous solutions of positively charged polyelectrolytes micelles doped with silver based nanoparticles with a polyanion. The micelles are formed by electrostatic interaction between two oppositely charged polymers, a polycation bearing 3,4-dihydroxyphenylalanine units (DOPA, a major component of natural adhesives) and a polyanion (poly(styrene sulfonate), PSS) without using any block copolymer. DOPA units are exploited for their well-known ability to anchor to stainless steel and to form and stabilize biocidal silver nanoparticles (Ag0). The chlorine counter-anion of the polycation forms and stabilizes biocidal silver chloride nanoparticles (AgCl). We demonstrate that two layers of micelles (alternated by PSS) doped by silver particles are enough to impart to the surface a strong antibacterial activity against Gram-negative E. coli. Moreover, micelles that are reservoirs of biocidal Ag+ can be easily reactivated after depletion. This novel water-based approach is convenient, simple and attractive for industrial applications.

Research Center/Unit :

Center for Education and Research on Macromolecules (CERM)

Disciplines :

Chemistry
Materials science & engineering

Author, co-author :

Falentin, Céline ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)

Faure, Emilie ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)

Svaldo Lanero, Tiziana ; Université de Liège - ULiège > Department of Chemistry > Nanochemistry and Molecular Systems (NANOCHEM)

Farina, Fabrice ; ArcelorMittal Liège Research, Liège, Belgium

Jérôme, Christine ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)

Van de Weerdt, Cécile ; Université de Liège - ULiège > Centre of Biomedical Integrative Genoproteomics (GIGA-R) > Laboratoire de Biologie Moléculaire et de Génie Génétique

Martial, Joseph ; Université de Liège - ULiège > Centre of Biomedical Integrative Genoproteomics (GIGA-R) > Laboratoire de Biologie Moléculaire et de Génie Génétique

Duwez, Anne-Sophie ; Université de Liège - ULiège > Department of Chemistry > Nanochemistry and Molecular Systems (NANOCHEM)

Detrembleur, Christophe ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)

Language :

English

Title :

Antibacterial polyelectrolyte micelles for coating stainless steel

Publication date :

08 May 2012

Journal title :

Langmuir

ISSN :

0743-7463

eISSN :

1520-5827

Publisher :

American Chemical Society, Washington, United States - District of Columbia

Volume :

Issue :

Pages :

7233-7241

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

http://pubs.acs.org/doi/pdf/10.1021/la3003965

Available on ORBi :

since 24 April 2012

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