Resting-state EEG study of comatose patients: a connectivity and frequency analysis to find differences between vegetative and minimally conscious states.
[en] The aim of this study was to look for differences in the power spectra and in EEG connectivity measures between patients in the vegetative state (VS/UWS) and patients in the minimally conscious state (MCS). The EEG of 31 patients was recorded and analyzed. Power spectra were obtained using modern multitaper methods. Three connectivity measures (coherence, the imaginary part of coherency and the phase lag index) were computed. Of the 31 patients, 21 were diagnosed as MCS and 10 as VS/UWS using the Coma Recovery Scale-Revised (CRS-R). EEG power spectra revealed differences between the two conditions. The VS/UWS patients showed increased delta power but decreased alpha power compared with the MCS patients. Connectivity measures were correlated with the CRS-R diagnosis; patients in the VS/UWS had significantly lower connectivity than MCS patients in the theta and alpha bands. Standard EEG recorded in clinical conditions could be used as a tool to help the clinician in the diagnosis of disorders of consciousness.
Research Center/Unit :
GIGA CRC (Cyclotron Research Center) In vivo Imaging-Aging & Memory - ULiège Communications and Remote Sensing Laboratory
Disciplines :
Neurology
Author, co-author :
Lehembre, Remy ; Université de Liège - ULiège > Centre de recherches du cyclotron
Bruno, Marie-Aurélie ; Université de Liège - ULiège > Centre de recherches du cyclotron
Soddu, Andrea ; Université de Liège - ULiège > Centre de recherches du cyclotron
Macq, Benoit
Laureys, Steven ; Université de Liège - ULiège > Centre de recherches du cyclotron
Noirhomme, Quentin ; Université de Liège - ULiège > Centre de recherches du cyclotron
Language :
English
Title :
Resting-state EEG study of comatose patients: a connectivity and frequency analysis to find differences between vegetative and minimally conscious states.
Alternative titles :
[fr] EEG de repos des patients comateux: analyse de connectivité et de fréquence pour trouver des différences entre états végétatifs et de conscience minimale
Publication date :
2012
Journal title :
Functional Neurology
ISSN :
0393-5264
eISSN :
1971-3274
Publisher :
CIC Edizioni Internationali, Roma, Italy
Volume :
27
Issue :
1
Pages :
41-47
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique European Commission (COST, DISCOS, MINDBRIDGE, DECODER) JSMF - James S McDonnell Foundation MSF - Mind Science Foundation
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