Familial adenomatous polyposis: clinical presentation, detection and surveillance.

Adenomatous Polyposis Coli/diagnosis/epidemiology/prevention & control; Disease Progression; Humans; Incidence; Mass Screening/methods; Population Surveillance/methods; Risk Factors

Abstract :

[en] Colorectal cancer (CRC) is a leading cause of cancer related death in the western countries. It remains an important health problem, often under-diagnosed. The symptoms can appear very late and about 25% of the patients are diagnosed at metastatic stage. Familial adenomatous polyposis (FAP) is an inherited colorectal cancer syndrome, characterized by the early onset of hundred to thousands of adenomatous polyps in the colon and rectum. Left untreated, there is a nearly 100% cumulative risk of progression to CRC by the age of 35-40 years, as well as an increased risk of various other malignancies. CRC can be prevented by the identification of the high risk population and by the timely implementation of rigid screening programs which will lead to special medico-surgical interventions.

Disciplines :

Gastroenterology & hepatology

Author, co-author :

Laurent, S.; Université de Liège - ULiège > HEC-Ecole de gestion : UER > Statistique appliquée à la gestion et à l'économie

Franchimont, D.

Coppens, J.P.

Leunen, K.

Macken, L.

Peeters, Marjan ; Université de Liège - ULiège > Département de droit > Département de droit

Plomteux, O.

POLUS, Marc ; Centre Hospitalier Universitaire de Liège - CHU > Gastro-Entérologie-Hépatologie

Poppe, B.

Sempoux, C.

More authors (6 more)

Language :

English

Title :

Familial adenomatous polyposis: clinical presentation, detection and surveillance.

Publication date :

2011

Journal title :

Acta Gastro-Enterologica Belgica

ISSN :

0001-5644

eISSN :

1784-3227

Publisher :

Acta Medica Belgica, Bruxelles, Belgium

Volume :

Issue :

Pages :

415-20

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 06 February 2012

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213 (6 by ULiège)

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2 (2 by ULiège)

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