Application of MRI for improved local control in complex radiotherapy of cervical cancer

Janaki, Hadjiev; Zsolt, Cselik; Péter Bogner; Árpád, Kovács; LAKOSI, Ferenc; Gyula, Kotek; Imre, Repa

doi:10.2298/AOO0604095H

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Application of MRI for improved local control in complex radiotherapy of cervical cancer

Janaki, Hadjiev; Zsolt, Cselik; Péter Bogner et al.

2006 • In Archive of Oncology, 14 (3-4), p. 95-100

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/110917

DOI
10.2298/AOO0604095H

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Keywords :

Uterine Cervical Neoplasms; ; ; ; ,; Interventional; Radiology; Dosage; Radiotherapy; Brachytherapy; Magnetic Resonance Imaging

Abstract :

[en] Background: The aim of this study was to analyze the use of magnetic resonance imaging (MRI) as a modern medical imaging technique in radiotherapy with special emphasis on the integration of MRI and a novel technique in brachytherapy to optimize treatment outcome in cervical cancer. Methods: In addition to the CT based shrinking volume conformal teletherapy in 31 patients with locally advanced cervical cancer, MRI examination with a special adjustable applicator at the treatment site was performed for the brachytherapy planning. To avoid excessive doses to the healthy structures during complex cervical radiotherapy isodose curves were calculated upon the information of the MR image and dose distribution was evaluated. Results: The consecutive application of CT and MRI limited the possibility for overdosage of the critical organs and undertreatment of the advanced tumor spread in all cases. The overall response rate for the complex treatment was 74.2% with complete regression in 25.8% of the cases. Based on the exact information of the three dimensional digital data radiation doses could be optimized without increasing the possibility of acute complications rate. Conclusion: The introduction of 3D treatment planning for teletherapy pelvic and boost irradiation of cervical carcinoma as well as for the brachytherapy part of the complex treatment is to be recommended.

Disciplines :

Oncology

Author, co-author :

Janaki, Hadjiev

Zsolt, Cselik

Péter Bogner

Árpád, Kovács

LAKOSI, Ferenc ; Centre Hospitalier Universitaire de Liège - CHU > Radiothérapie

Gyula, Kotek

Imre, Repa

Language :

English

Title :

Application of MRI for improved local control in complex radiotherapy of cervical cancer

Publication date :

December 2006

Journal title :

Archive of Oncology

ISSN :

0354-7310

eISSN :

1450-9520

Publisher :

Institute of Oncology Sremska Kamenica, Serbia

Volume :

Issue :

3-4

Pages :

95-100

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 02 February 2012

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Bibliography

McCarthy, S., The uterus and vagina (1974) Magnetic resonance imaging of the body, pp. 761-814. , Higgins CB, Hricak H, Helms CA, editors, 3rd ed. New York: Lippincott-Raven
Reinhold, C., Uterus and cervix (1997) MRI of the abdomen and pelvis: A text atlas, pp. 585-660. , Semelka RC, Ascher SM, Reinhold C, editors, New York: Wiley-Liss
Subak, L.L., Hricak, H., Powell, B., Azizi, L., Stern, J.L., Cervical carcinoma: Computed tomography and magnetic resonance imaging for preoperative staging (1995) Obstet Gynecol, 86, pp. 43-50
Togashi, K., Morikawa, K., Kataoka, M.L., Konishi, J., Cervical cancer (1998) J Magn Reson Imaging, 8, pp. 391-397
Choi, S.H., Kim, S.H., Choi, H.J., Park, B.K., Lee, H.J., Preoperative magnetic resonance imaging staging of uterine cervical carcinoma: Results of prospective study (2004) J Comput Assist Tomogr, 28 (5), pp. 620-627
Okamoto, Y., Tanaka, Y.O., Nishida, M., Tsunoda, H., Yoshikawa, H., Itai, Y., MR imaging of the uterine cervix: Imaging-pathologic correlation (2003) Radiographics, 23 (2), pp. 425-445
Özsarlak, O., Tjalma, W., Schepens, E., Corthouts, B., Op de Beck, B., Van Marck, E., The correlation of preoperative CT, MR imaging, and clinical staging (FIGO) with histopathology findings in primary cervical carcinoma (2003) Eur Radiol, 13 (10), pp. 2338-2345
Pötter, R., Haie-Meder, C., Van Limbergen, E., Barillot, I., De Brabandere, M., Dimopoulos, J., Recommendations from gynaecological (GYN) GEC ESTRO working group (II): Concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology (2006) Radiother Oncol, 78 (1), pp. 67-77
Hadjiev, J., Antal, G., Antalffy, Z., Bogner, P., Esik, O., Repa, I., A novel technique with a flexible applicator fpr MRI-based brachytherapy of cervical cancer (2004) Eur J Gynaecol Oncol, 3, pp. 347-350
Dose and Volume Specification for Reporting Intracavitary Therapy in Gynecology (1985) ICRU Report, 38. , International Commission on Radiation Units and Measurements ICRU, Bethesda, MD
ICRU
Pötter, R., Van Limbergen, E., Gerstner, N., Wambersie, A., Survey of the use of the ICRU 38 in recording and reporting cervical cancer brachytherapy (2001) Radiother Oncol, 58 (1), pp. 11-18
Elhanafy, O.A., Das, R.K., Paliwal, B.R., Migahed, M.D., Sakr, H.A., Elleithy, M., Anatomic variation of prescription points and treatment volume with fractionated high-dose rate gynecological brachytherapy (2002) J Appl Clin Med Phys, 1, pp. 1-5
Dimopoulos, J., Lang, S., Kristis, C., Böswarth, J., Bauer, N., Wachter-Gerstner, N., Combined MRI-based intracavitary and interstitial brachytherapy for locally advanced cervical cancer with a modified tandem ring applicator-clinical feasibility and preliminary results (2004) Radiother Oncol, 71, pp. S10
Therasse, P., Arbuck, S.G., Eisenhauer, E.A., Wanders, J., Kaplan, R.S., Rubinstein, L., New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada (2000) J Nat Cancer Inst, 92 (3), pp. 205-216
Bies, J.R., Ellis, J.H., Kopecky, K.K., Sutton, J.P., Klatte, E.C., Stehman, F.B., Assessment of primary gynecologic malignancies: Comparison of 0.15-T resistive MRI with CT (1984) AJR Am J Roentgenol, 143 (6), pp. 1249-1257
Cobby, M., Browning, J., Jones, A., Whipp, E., Goddard, P., Magnetic resonance imaging, computed tomography and endosonography in the local staging of carcinoma of the cervix (1990) Br J Radiol, 63 (753), pp. 673-679
Michniewicz K, Oellinger J. Diagnostic imaging in invasive cervical carcinoma: MRI, CT, and ultrasonography. Zentralbl Gynakol 2001
123(4):222-8
Oellinger, J.J., Blohmer, J.U., Michniewicz, K., Siewert, C., Wust, P., Gutberlet, M., Pre-operative staging of cervical cancer: Comparison of magnetic resonance imaging (MRI) and computed tomography (CT) with histologic results (2000) Zentralbl Gynekol, 122 (2), pp. 82-91
Pecorelli, S., Odicino, F., Cervical cancer staging (2003) Cancer J, 9 (5), pp. 390-394
Fellner, C., Pötter, R., Knocke, T., Wambersie, A., Comparison of radiography and computed tomography-based treatment planning in cervix cancer in brachytherapy with specific attention to some quality assurance aspects (2001) Radiother Oncol, 58 (1), pp. 53-62
Haie-Meder, C., Potter, R., Van Limbergen, E., Briot, E., De Brabandere, M., Dimopoulos, J., Gynaecological (GYN) GEC-ESTRO Working Group. Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): Concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV (2005) Radiother Oncol, 74 (3), pp. 235-245
Nicolet, V., Carignan, L., Bourdon, F., Prosmanne, O., MR imaging of cervical carcinoma: A practical staging approach (2000) Radiographics, 20 (1), pp. 1539-1549
Schoeppel, S.L., Ellis, J.H., LaVigne, M.L., Schea, R.A., Roberts, J.A., Magnetic resonance imaging during intracavitary gynecologic brachytherapy (1992) Int J Radiat Oncol Biol Phys, 23 (1), pp. 169-174
Tardivon, A.A., Kinkel, K., Lartigau, E., Masselot, J., Gerbaulet, A.P., Vanel, D., MR imaging during intracavitary brachytherapy of vaginal and cervical cancer: Preliminary results (1996) Radiographics, 16 (6), pp. 1363-1370
Datta, N.R., Basu, R., Das, K.J., Rajasekar, D., Pandey, C.M., Ayyagari, S., Problems in reporting doses and volumes during multiple high-dose-rate intracavitary brachytherapy for carcinoma cervix as per ICRU Report 38: A comparative study using flexible and rigid applicators (2003) Gynecol Oncol, 2, pp. 285-292
Mai, J., Erickson, B., Rownd, J., Gin, M., Comparison of four different dose specification methods for high-dose-rate intracavitary radiation for treatment of cervical cancer (2001) Int J Radiat Oncol Biol Phys, 51 (4), pp. 1131-1141
Ohizumi, Y., Akiba, T., Imamiya, S., Tamai, Y., Mori, T., Shinozuka, T., Vaginal applicators (ovoids) for local control and alleviation of rectal complications of cervical cancers treated by brachytherapy (1999) Tokai J Exp Clin Med, 24 (1), pp. 2-7
Potter, R., Kirisits, C., Lievens, Y., What kind of equipment do we need in gynecological brachytherapy? Clinical, technical and economical aspects for standard and new techniques (2005) Radiother Oncol, 75 (SUPPL.), p. 1. , S
Kirisits, C., Potter, R., Lang, S., Dimopoulos, J., Wachter-Gerstner, N., Georg, D., Dose and volume parameters for MRI-based treatment planning in intracavitary brachytherapy for cervical cancer (2005) Int J Radiat Oncol Biol Phys, 62 (3), pp. 901-911