Article (Scientific journals)
Revelations from the unconscious: studying residual brain function in coma and related states.
Laureys, Steven; Boly, Mélanie; Schnakers, Caroline et al.
2008In Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique, 163 (7-9), p. 381-8; discussion 388-90
 

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Keywords :
Brain/physiopathology; Brain Death/diagnosis/physiopathology; Brain Injuries/complications/physiopathology; Brain Mapping; Coma/diagnosis/etiology/physiopathology; Disability Evaluation; Electroencephalography; Ethics, Clinical; Glasgow Coma Scale; Humans; Magnetic Resonance Imaging; Persistent Vegetative State/diagnosis/etiology/physiopathology; Positron-Emission Tomography; Predictive Value of Tests; Recovery of Function; Sensitivity and Specificity; Severity of Illness Index; Unconsciousness/physiopathology
Abstract :
[en] The purpose of our research is to contribute to a better understanding of the residual brain function of patients who survive an acute brain damage but remain in a coma, vegetative state, minimally conscious state or locked-in syndrome. The diagnosis, prognosis, therapy and medical management of these patients remain difficult. These studies are also of interest scientifically, as they help to elucidate the neural correlates of human consciousness. We here review our studies on bedside behavioral evaluation scales, electrophysiology and functional neuroimaging in these disorders of consciousness and conclude by discussing methodological and ethical issues and current concepts of the standards for care and quality of life in these challenging conditions.
Disciplines :
Neurology
Author, co-author :
Laureys, Steven  ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Boly, Mélanie ;  Université de Liège - ULiège > Département des sciences cliniques > Neurologie
Schnakers, Caroline ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Vanhaudenhuyse, Audrey  ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Bruno, Marie-Aurélie ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Noirhomme, Quentin ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Ledoux, Didier  ;  Centre Hospitalier Universitaire de Liège - CHU > Soins intensifs
Faymonville, Marie-Elisabeth ;  Centre Hospitalier Universitaire de Liège - CHU > Algologie - soins palliatifs
Lamy, Maurice ;  Centre Hospitalier Universitaire de Liège - CHU > Anesthésie et réanimation
Franck, Georges 
Luxen, André ;  Université de Liège - ULiège > Département de chimie (sciences) > Chimie organique de synthèse - Centre de recherches du cyclotron
Maquet, Pierre  ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Moonen, Gustave  ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
More authors (3 more) Less
Language :
English
Title :
Revelations from the unconscious: studying residual brain function in coma and related states.
Publication date :
2008
Journal title :
Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique
ISSN :
0377-8231
Publisher :
Académie Royale de Médecine de Belgique, Bruxelles, Belgium
Volume :
163
Issue :
7-9
Pages :
381-8; discussion 388-90
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