Le medicament du mois. Lowette, un contraceptif pour traiter l'acne de la jeune femme.

Acne Vulgaris/drug therapy; Contraceptives, Oral, Synthetic/therapeutic use; Dose-Response Relationship, Drug; Estradiol Congeners/therapeutic use; Ethinyl Estradiol/therapeutic use; Female; Humans; Levonorgestrel/therapeutic use

Abstract :

[en] Acne is a multifactorial disorder affecting the vast majority of adolescents and young adults. Among the therapeutic armamentum, estroprogestative contraception can be offered to young women. The choice must, however, be carefully targeted because the estroprogestative associations do not show similar anti-acne efficacy. A new contraceptive associating 20 micrograms of ethinyl estradiol and 100 micrograms of levonorgestrel (Lowette) has proven its clinical efficacy in this indication.

Disciplines :

Dermatology

Author, co-author :

Goffin, Véronique ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Pierard, Claudine ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Pierard, Gérald ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Language :

French

Title :

Le medicament du mois. Lowette, un contraceptif pour traiter l'acne de la jeune femme.

Alternative titles :

[en] Medication of the month. Lowette, a contraceptive for treating acne in young women

Publication date :

2003

Journal title :

Revue Médicale de Liège

ISSN :

0370-629X

eISSN :

2566-1566

Publisher :

Université de Liège. Revue Médicale de Liège, Liège, Belgium

Volume :

Issue :

Pages :

261-3

Peer reviewed :

Peer reviewed

Available on ORBi :

since 14 April 2009

Statistics

Number of views

228 (3 by ULiège)

Number of downloads

377 (3 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenAlex citations

Bibliography

Piérard GE. - Quelles sont la définition et la pathogénie de l'acné? in Acné en 25 questions. Ed. par H. Degreef, J.M. Lachapelle, G.E. Piérard. Publ. Galderma Belgilux, 1999, 15-24.
Toyoda M, Morohashi M. - Pathogenesis of acne. Med Electron Microsc, 2001, 34, 29-40.
Cibula D, Hill M, Vohradnikova O, et al. - The role of androgens in determining acne severity in adult women. Br J Dermatol, 2000, 143, 399-404.
Thiboutot D, Chen WC. - Update and future of hormonal therapy in acne. Dermatology, 2003, 206, 57-67.
Palatsi R, Hirvensalo E, Liukko P, et al. - Serum total and unbound testosterone and sex hormone binding globulin (SHBG) in female acne patients treated with two different oral contraceptives. Acta Derm venereol, 1984, 64, 517-523.
Mango D, Ricci S, Manna P, et al. - Clinical and hormonal effects of ethinylestradiol combined with gestodene and desogestrel in young women with acne vulgaris. Contraception, 1996, 53, 163-170.
Lemay A, Poulin Y. - Oral contraceptives as anti-androgenic treatment of acne. J Obstet Gynaecol Can, 2002, 24, 559-567.
Thiboutot D, Gilliland K, Light J, Lookingbill D. Androgen metabolism in sebaceous glands from subjects with and without acne. Arch Dermatol, 1999, 135, 1041-1045.
Lucky AW, Henderson TA, Olson WH, et al. - Effectiveness of norgestimate and ethinyl estradiol in treating moderate acne vulgaris. J Am Acad Dermatol, 1997, 37, 746-754.
Redmond GP, Olson WH, Lippman JS, et al. - Norgestimate and ethinyl estradiol in the treatment of acne vulgaris: a randomized, placebo-controlled trial. Obstet Gynecol, 1997, 89, 615-622.
Thiboutot D, Archer D, Lemay A, et al. - A randomized, controlled trial of a low dose contraceptive containing 20 μg of ethinyl estradiol and 100 μg of levonorgestrel for acne treatment. Fertil Steril, 2001, 76, 461-468.
Leyden J, Shalita A, Hordinsky M, et al. - Efficacy of a low-dose oral contraceptive containing 20 μg of ethinyl estradiol and 100 μg of levonorgestrel for the treatment of moderate acne: a randomized, placebo-controlled trial. J Am Acad Dermatol, 2002, 47, 399-409.
Olson WH, Lippman JS, Robisch DM. - The duration of response to norgestimate and ethinyl estradiol in the treatment of acne vulgaris. Int J Fertil Wom Med, 1998, 43, 286-290.
Piérard-Franchimont C, Gaspard V, Lacante P, et al. - A quantitative biometrological assessment of acne and hormonal evaluation in young women using a triphasic low-dose oral contraceptive containing gestodene. Eur J Contracept Reprod Health Care, 2000, 5, 275-286.
Piérard-Franchimont C, Goffin V, Arrese JE, et al. Lymecycline and minocycline in inflammatory acne. A randomized, double-blind study on clinical and in vivo antibacterial efficacy. Skin Pharmacol Appl Skin Physiol, 2002, 15, 112-119.
Uhoda E, Piérard-Franchimont C, Piérard GE. - Comedolysis by α lipohydroxyacid formulation in acne prone subjects. Eur J Dematol, 2003, 13, 65-68.
Thorneycroft IH, Stanczyk FZ, Bradshaw KD, et al. Effect of low-dose oral contraceptives on androgenic markers and acne. Contraception, 1999, 60, 255-262.
Archer DF, Maheux R, DelConte A, et al. - A new low-dose monophasic combination oral contraceptive (Alesse®) with levonorgestrel 100 μg and ethinyl estradiol 20 μg. Contraception, 1997, 55, 139-144.
Archer DF, Maheux R, DelConte A, et al. - Efficacy and safety of a low-dose monophasic combination oral contraceptive containing 100 μg levonorgestrel and 20 μg ethinyl estradiol (Alesse®). Am J Obstet Gynecol, 1999, 181, S30-S44.
Coney P, Washenik K, Langley RGB, et al. - Weight change and adverse event incidence with a low-dose oral contraceptive: two randommized, placebo-controlled trials. Contraception, 2001, 63, 297-302.
Van Hooff MHA, Hirasing RA, Kaptein MBM, et al. The use of oral contraceptives by adolescents for contraception, menstrual cycle problems or acne. Acta Obstet Gynecol Scand, 1998, 77, 898-904.