Regional brain activity during working memory tasks

[en] The first aim of our PET study was to replicate previous findings concerning the brain areas activated by a verbal working memory task. The second aim was to specify the neural basis of the central executive, using a task of working memory updating. Our data confirm that the lower left supramarginal gyms and premotor area are the key regions subserving short-term verbal memory processes. They also suggest that the updating memory task is related to mid-dorsolateral prefrontal activation most probably responsible for the updating function of the central executive. An unexpected, predominantly right activation occurred in the inferior parietal region during the verbal memory updating task, which we related to a visuospatial strategy used to maintain the information in short-term memory. A third purpose was to explore the brain regions activated by a nonverbal, visual memory task, and our results confirm the importance of the superior occipital gyrus in the visual short-term memory.

Research center :

GIGA CRC (Cyclotron Research Center) In vivo Imaging-Aging & Memory - ULiège

Disciplines :

Neurology
Neurosciences & behavior

Author, co-author :

Salmon, Eric ; Université de Liège - ULiège > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et révalid. cogn.

Van der Linden, Martial ; Université de Liège - ULiège > Département des sciences cognitives > Psychopathologie cognitive

Collette, Fabienne ; Université de Liège - ULiège > Département des sciences cognitives > Neuropsychologie

Delfiore, Guy

Maquet, Pierre ; Université de Liège - ULiège > Centre de recherches du cyclotron

Degueldre, Christian ; Université de Liège - ULiège > Centre de recherches du cyclotron

Luxen, André ; Université de Liège - ULiège > Département de chimie (sciences) > Chimie organique de synthèse - Centre de recherches du cyclotron

Franck, Georges ; Université de Liège - ULiège > Relations académiques et scientifiques (Médecine)

Language :

English

Title :

Regional brain activity during working memory tasks

Publication date :

October 1996

Journal title :

Brain: a Journal of Neurology

ISSN :

0006-8950

eISSN :

1460-2156

Publisher :

Oxford University Press

Volume :

119

Issue :

Pt 5

Pages :

1617-1625

Peer reviewed :

Peer Reviewed verified by ORBi

Funders :

F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE]

Available on ORBi :

since 27 January 2012

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Scopus citations^®

275

Scopus citations^®
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248

OpenCitations

227

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