Evaluation of the lipid-drug association constant in model membranes: A monolayer approach

[en] A general procedure of evaluation of the lipid-drug association constant in monolayer is presented. Lipids are spread at the air-water interface and the drugs injected into the aqueous subphase. Association constant potential and predictions from the Gouy-Chapman theory. Several procedures of calculation are described.

Disciplines :

Biochemistry, biophysics & molecular biology

Author, co-author :

Goormaghtigh, E.

Brasseur, Robert ; Université de Liège - ULiège > Chimie et bio-industries > Centre de Bio. Fond. - Section de Biophysique moléc. numér.

Vanderbranden, M.

Caspers, J.

Ruysschaert, J. M.

Language :

English

Title :

Evaluation of the lipid-drug association constant in model membranes: A monolayer approach

Publication date :

September 1982

Journal title :

Bioelectrochemistry and Bioenergetics

ISSN :

0302-4598

Publisher :

Elsevier, Netherlands

Volume :

Issue :

Pages :

489-498

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 20 January 2012

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Bibliography

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