The presence of bluetongue virus serotype 8 RNA in Belgian cattle since 2008.

[en] After a short winter break, bluetongue virus serotype 8 was responsible in 2007 for a large-scale epidemic among ruminant populations in Western Europe. Little is known about the mechanisms allowing the virus to survive winter conditions. A yearly mass vaccination of cattle and sheep started in spring 2008, which was recognized as successful in terms of clinical protection, but occult circulation of the bluetongue virus has not been adequately addressed. We studied the carriage of bluetongue RNA in the spleen of cattle in the vector-free period and the circulation of bluetongue virus in cattle populations in Belgium since the introduction of vaccination programmes. Overall, the results presented here show evidence for the long-term carriage of bluetongue virus RNA in the spleen of cattle and demonstrated a low but significant circulation and transplacental transmission of bluetongue virus in Belgian cattle in 2009, with apparent disappearance in 2010.

Disciplines :

Microbiology

Author, co-author :

Garigliany, Mutien-Marie ; Université de Liège - ULiège > Département de morphologie et pathologie > Pathologie spéciale et autopsies

Desmecht, Daniel ; Université de Liège - ULiège > Département de morphologie et pathologie > Pathologie spéciale et autopsies

De Clercq, Kris; Centre d'Etudes et de Recherches Vétérinaires Agronomiques = Centrum voor Onderzoek in Diergeneeskunde en Agrochemie - CERVA=CODA > Virologie

Language :

English

Title :

The presence of bluetongue virus serotype 8 RNA in Belgian cattle since 2008.

Publication date :

December 2011

Journal title :

Transboundary and Emerging Diseases

ISSN :

1865-1674

eISSN :

1865-1682

Publisher :

Wiley, Berlin, Germany

Volume :

Issue :

Pages :

503-509

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 19 January 2012

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Bibliography

Akey, D.H., A.J. Luedke, and R.H. Jones, 1985: Salivary gland homogenates from the vector Culicoides variipennis may aid in detection of bluetongue virus in chronically infected cattle. Prog. Clin. Biol. Res. 178, 135-145.
Backx, A., R. Heutink, E. van Rooij, and P. van Rijn, 2009: Transplacental and oral transmission of wild-type bluetongue virus serotype 8 in cattle after experimental infection. Vet. Microbiol. 138, 235-243.
Bartram, D.J., L. Heasman, C.A. Batten, C.A. Oura, J. Plana-Duran, H.M. Yuen, and A.D. Wylie, 2011: Neutralising antibody responses in cattle and sheep following booster vaccination with two commercial inactivated bluetongue virus serotype 8 vaccines. Vet. J. 188, 193-196.
Bowne, J.G., A.J. Luedke, M.M. Jochim, and H.E. Metcalf, 1968: Bluetongue disease in cattle. J. Am. Vet. Med. Assoc. 153, 662-668.
Calistri, P., A. Giovannini, G. Savini, L. Bonfanti, P. Cordioli, R. Lelli, and V. Caporale, 2010: Antibody response in cattle vaccinated against bluetongue serotype 8 in Italy. Transbound. Emerg. Dis. 57, 180-184.
Carpenter, S., A. Wilson, and P.S. Mellor, 2009: Culicoides and the emergence of bluetongue virus in northern Europe. Trends Microbiol. 17, 172-178.
Darpel, K.E., C.A. Batten, E. Veronesi, S. Williamson, P. Anderson, M. Dennison, S. Clifford, C. Smith, L. Philips, C. Bidewell, K. Bachanek-Bankowska, A. Sanders, A. Bin-Tarif, A.J. Wilson, S. Gubbins, P.P. Mertens, C.A. Oura, and P.S. Mellor, 2009: Transplacental transmission of bluetongue virus 8 in cattle, UK. Emerg. Infect. Dis. 15, 2025-2028.
De Clercq, K., I. De Leeuw, B. Verheyden, E. Vandemeulebroucke, T. Vanbinst, C. Herr, E. Meroc, G. Bertels, N. Steurbaut, C. Miry, K. De Bleecker, G. Maquet, J. Bughin, M. Saulmont, M. Lebrun, B. Sustronck, R. De Deken, J. Hooyberghs, P. Houdart, M. Raemaekers, K. Mintiens, P. Kerkhofs, N. Goris, and F. Vandenbussche, 2008: Transplacental infection and apparently immunotolerance induced by a wild-type bluetongue virus serotype 8 natural infection. Transbound. Emerg. Dis. 55, 352-359.
Desmecht, D., R.V. Bergh, A. Sartelet, M. Leclerc, C. Mignot, F. Misse, C. Sudraud, S. Berthemin, S. Jolly, B. Mousset, A. Linden, F. Coignoul, and D. Cassart, 2008: Evidence for transplacental transmission of the current wild-type strain of bluetongue virus serotype 8 in cattle. Vet. Rec. 163, 50-52.
Eschbaumer, M., B. Hoffmann, P. Konig, J.P. Teifke, J.M. Gethmann, F.J. Conraths, C. Probst, T.C. Mettenleiter, and M. Beer, 2009: Efficacy of three inactivated vaccines against bluetongue virus serotype 8 in sheep. Vaccine 27, 4169-4175.
Gethmann, J., K. Huttner, H. Heyne, C. Probst, M. Ziller, M. Beer, B. Hoffmann, T.C. Mettenleiter, and F.J. Conraths, 2009: Comparative safety study of three inactivated BTV-8 vaccines in sheep and cattle under field conditions. Vaccine 27, 4118-4126.
Gibbs, E.P., M.J. Lawman, and K.A. Herniman, 1979: Preliminary observations on transplacental infection of bluetongue virus in sheep-a possible overwintering mechanism. Res. Vet. Sci. 27, 118-120.
Hofmann, M.A., S. Renzullo, M. Mader, V. Chaignat, G. Worwa, and B. Thuer, 2008: Genetic characterization of toggenburg orbivirus, a new bluetongue virus, from goats, Switzerland. Emerg. Infect. Dis. 14, 1855-1861.
Hourrigan, J.L., and A.L. Klingsporn, 1975: Bluetongue: the disease in cattle. Aust. Vet. J. 51, 170-174.
Kettle, D.S., 1969: The ecology and control of blood-sucking ceratopogonids. Acta Trop. 26, 235-248.
Losson, B., B. Mignon, J. Paternostre, M. Madder, R. De Deken, G. De Deken, I. Deblauwe, C. Fassotte, R. Cors, T. Defrance, J.C. Delecolle, T. Baldet, E. Haubruge, F. Frederic, J. Bortels, and G. Simonon, 2007: Biting midges overwintering in Belgium. Vet. Rec. 160, 451-452.
Luedke, A.J., R.H. Jones, and T.E. Walton, 1977: Overwintering mechanism for bluetongue virus: biological recovery of latent virus from a bovine by bites of Culicoides variipennis. Am. J. Trop. Med. Hyg. 26, 313-325.
Maclachlan, N.J., and B.I. Osburn, 2008: Induced brain lesions in calves infected with bluetongue virus. Vet. Rec. 162, 490-491.
Maclachlan, N.J., C.P. Drew, K.E. Darpel, and G. Worwa, 2009: The pathology and pathogenesis of bluetongue. J. Comp. Pathol. 141, 1-16.
Mayo, C.E., B.M. Crossley, S.K. Hietala, I.A. Gardner, R.E. Breitmeyer, and N.J. Maclachlan, 2010: Colostral transmission of bluetongue virus nucleic acid among newborn dairy calves in California. Transbound. Emerg. Dis. 57, 277-281.
Mellor, P.S., 1990: The replication of bluetongue virus in Culicoides vectors. Curr. Top. Microbiol. Immunol. 162, 143-161.
Mellor, P.S., S. Carpenter, L. Harrup, M. Baylis, and P.P. Mertens, 2008: Bluetongue in Europe and the Mediterranean Basin: history of occurrence prior to 2006. Prev. Vet. Med. 87, 4-20.
Melville, L.F., N.T. Hunt, S.S. Davis, and R.P. Weir, 2004: Bluetongue virus does not persist in naturally infected cattle. Vet. Ital. 40, 502-507.
Menzies, F.D., S.J. McCullough, I.M. McKeown, J.L. Forster, S. Jess, C. Batten, A.K. Murchie, J. Gloster, J.G. Fallows, W. Pelgrim, P.S. Mellor, and C.A. Oura, 2008: Evidence for transplacental and contact transmission of bluetongue virus in cattle. Vet. Rec. 163, 203-209.
Meroc, E., C. Herr, B. Verheyden, J. Hooyberghs, P. Houdart, M. Raemaekers, F. Vandenbussche, K. De Clercq, and K. Mintiens, 2009: Bluetongue in Belgium: episode II. Transbound. Emerg. Dis. 56, 39-48.
Nielsen, S.A., B.O. Nielsen, and J. Chirico, 2010: Monitoring of biting midges (Diptera: Ceratopogonidae: Culicoides Latreille) on farms in Sweden during the emergence of the 2008 epidemic of bluetongue. Parasitol. Res. 106, 1197-1203.
Nunamaker, R.A., P.J. Sieburth, V.C. Dean, J.G. Wigington, C.E. Nunamaker, and J.O. Mecham, 1990: Absence of transovarial transmission of bluetongue virus in Culicoides variipennis: immunogold labelling of bluetongue virus antigen in developing oocytes from Culicoides variipennis (Coquillett). Comp. Biochem. Physiol. A Comp. Physiol. 96, 19-31.
Oura, C.A., J.L. Wood, A.J. Sanders, A. Bin-Tarif, M. Henstock, L. Edwards, T. Floyd, H. Simmons, and C.A. Batten, 2009: Seroconversion, neutralising antibodies and protection in bluetongue serotype 8 vaccinated sheep. Vaccine 27, 7326-7330.
Oura, C.A., J.L. Wood, T. Floyd, A.J. Sanders, A. Bin-Tarif, M. Henstock, L. Edwards, H. Simmons, and C.A. Batten, 2010: Colostral antibody protection and interference with immunity in lambs born from sheep vaccinated with an inactivated Bluetongue serotype 8 vaccine. Vaccine 28, 2749-2753.
Purse, B.V., P.S. Mellor, D.J. Rogers, A.R. Samuel, P.P. Mertens, and M. Baylis, 2005: Climate change and the recent emergence of bluetongue in Europe. Nat. Rev. Microbiol. 3, 171-181.
Saegerman, C., B. Bolkaerts, C. Baricalla, M. Raes, L. Wiggers, I. de Leeuw, F. Vandenbussche, J.Y. Zimmer, E. Haubruge, D. Cassart, K. De Clercq, and N. Kirschvink, 2011: The impact of naturally-occurring, trans-placental bluetongue virus serotype-8 infection on reproductive performance in sheep. Vet. J. 187, 72-80.
Santman-Berends, I.M., L. van Wuijckhuise, P. Vellema, and P.A. van Rijn, 2010: Vertical transmission of bluetongue virus serotype 8 virus in Dutch dairy herds in 2007. Vet. Microbiol. 141, 31-35.
Steinrigl, A., S. Revilla-Fernandez, M. Eichinger, J. Koefer, and P. Winter, 2010: Bluetongue virus RNA detection by RT-qPCR in blood samples of sheep vaccinated with a commercially available inactivated BTV-8 vaccine. Vaccine 28, 5573-5581.
Takamatsu, H., P.S. Mellor, P.P. Mertens, P.A. Kirkham, J.N. Burroughs, and R.M. Parkhouse, 2003: A possible overwintering mechanism for bluetongue virus in the absence of the insect vector. J. Gen. Virol. 84, 227-235.
Toussaint, J.F., C. Sailleau, E. Breard, S. Zientara, and K. De Clercq, 2007a: Bluetongue virus detection by two real-time RT-qPCRs targeting two different genomic segments. J. Virol. Methods 140, 115-123.
Toussaint, J.F., C. Sailleau, J. Mast, P. Houdart, G. Czaplicki, L. Demeestere, F. VandenBussche, W. van Dessel, N. Goris, E. Breard, L. Bounaadja, T. Etienne, S. Zientara, and K. De Clercq, 2007b: Bluetongue in Belgium, 2006. Emerg. Infect. Dis. 13, 614-616.
Vandemeulebroucke, E., K. De Clercq, Y. Van der Stede, and F. Vandenbussche, 2010: A proposed validation method for automated nucleic acid extraction and RT-qPCR analysis: an example using Bluetongue virus. J. Virol. Methods 165, 76-82.
Vandenbussche, F., I. De Leeuw, E. Vandemeulebroucke, and K. De Clercq, 2009: Emergence of bluetongue serotypes in Europe, part 1: description and validation of four real-time RT-PCR assays for the serotyping of bluetongue viruses BTV-1, BTV-6, BTV-8 and BTV-11. Transbound. Emerg. Dis. 56, 346-354.
Wackerlin, R., M. Eschbaumer, P. Konig, B. Hoffmann, and M. Beer, 2010: Evaluation of humoral response and protective efficacy of three inactivated vaccines against bluetongue virus serotype 8 one year after vaccination of sheep and cattle. Vaccine 28, 4348-4355.
White, D.M., W.C. Wilson, C.D. Blair, and B.J. Beaty, 2005: Studies on overwintering of bluetongue viruses in insects. J. Gen. Virol. 86, 453-462.
Wilson, A., K. Darpel, and P.S. Mellor, 2008: Where does bluetongue virus sleep in the winter? PLoS Biol. 6, e210.
Wouda, W., M.P. Roumen, N.H. Peperkamp, J.H. Vos, E. van Garderen, and J. Muskens, 2008: Hydranencephaly in calves following the bluetongue serotype 8 epidemic in the Netherlands. Vet. Rec. 162, 422-423.
Zientara, S., N.J. MacLachlan, P. Calistri, J.M. Sanchez-Vizcaino, and G. Savini, 2010: Bluetongue vaccination in Europe. Expert Rev. Vaccines 9, 989-991.
Zimmer, J.Y., C. Saegerman, B. Losson, and E. Haubruge, 2010: Breeding sites of bluetongue virus vectors, belgium. Emerg. Infect. Dis. 16, 575-576.