Article (Scientific journals)
Analytic assessment under ultraviolet light of actinic lentigines under bleaching treatment.
PIERARD, Gérald; Seite, Sophie; Rougier, Andre et al.
2011In Journal of Cosmetic Dermatology, 10 (2), p. 104-9
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Keywords :
Antioxidants/therapeutic use; Bleaching Agents/therapeutic use; Cosmetic Techniques; Female; Glycolates/therapeutic use; Humans; Image Enhancement/methods; Keratolytic Agents/therapeutic use; Lentigo/diagnosis/drug therapy/etiology; Pyrones/therapeutic use; Sunlight/adverse effects; Ultraviolet Rays/diagnostic use
Abstract :
[en] BACKGROUND: Actinic (solar) lentigines are melanotic tumors frequently developed during photoaging on the dorsum of the hands. Bleaching (whitening) agents are commonly offered to fade their darker aspect. In general, regular colorimetric methods show poor sensitivity to disclose any bleaching effect. METHOD: The present randomized controlled study on 24 women was designed to objectively assess the clinical efficacy of a combination of bleaching agents on actinic lentigines. In the endeavor of improving sensitivity, the ultraviolet light-enhanced visualization (ULEV) method was used to derive analytical measurements of lentigo areas and darkness. The test product was a commercially available formulation associating glycolic acid, kojic acid, lipohydroxyacid, and a Vitreoscilla extract. The Analysis(R) Olympus and Adobe Photoshop(R) quantitative methods were applied to the ULEV pictures. RESULTS: Data indicated a rapid bleaching effect arising as early as after 1 month of daily applications. The effect progressively increased over 3 months of therapy. CONCLUSION: The presently described analytical method appears to be sensitive to document some bleaching effects on actinic lentigines.
Disciplines :
Dermatology
Author, co-author :
PIERARD, Gérald ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
Seite, Sophie
Rougier, Andre
QUATRESOOZ, Pascale  ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
Language :
English
Title :
Analytic assessment under ultraviolet light of actinic lentigines under bleaching treatment.
Publication date :
2011
Journal title :
Journal of Cosmetic Dermatology
ISSN :
1473-2130
eISSN :
1473-2165
Publisher :
Blackwell Publishing
Volume :
10
Issue :
2
Pages :
104-9
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
(c) 2011 Wiley Periodicals, Inc.
Available on ORBi :
since 27 December 2011

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