Abstract :
[en] Pancreas preservation by cold storage using University of Wisconsin solution was the
<br />mainstay method used for pancreas transplantation during the past 2 decades. Other
<br />solutions, such as HTK, Celsior, and SCOT 15, could not demonstrate any advantage for
<br />short preservation periods. But the advent of clinical islet transplantation and the larger
<br />use of controlled non–heart-beating donors have prompted the transplantation community
<br />to develop methods for increasing pancreas graft quality while preventing ischemic
<br />reperfusion damages. Oxygenation by 1- or 2-layer methods during pancreas preservation,
<br />as well as the use of perfluorocarbons, might increase the islet yield. Based on the former
<br />methods, there is a renewed interest in machine perfusion and oxygenation in pancreas
<br />preservation for pancreas transplantation and islet preparation.
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