Reference : Endometrial laser intrauterine thermotherapy: the first series of 100 patients observ...
Scientific journals : Article
Human health sciences : Reproductive medicine (gynecology, andrology, obstetrics)
Endometrial laser intrauterine thermotherapy: the first series of 100 patients observed for 1 year
Donnez, Jacques [ > > ]
Polet, Roland [ > > ]
Rabinovitz, Rafi [ > > ]
Maksude, Ak [ > > ]
Squifflet, Jean [ > > ]
NISOLLE, Michelle mailto [Centre Hospitalier Universitaire de Liège - CHU > > Gynécologie-Obstétrique CHR >]
Fertility and Sterility
Yes (verified by ORBi)
New York
[en] Endometrial ablation ; amenorrhea ; dysfunctional uterine bleeding
[en] Objective: To describe a new instrument (GyneLase®) that offers a new approach (endometrial laser intrauterine thermal therapy [ELITT]) to treatment of menorrhagia and to evaluate the efficacy of ELITT in the management of dysfunctional uterine bleeding.

Design: Prospective study.

Setting: University hospital.

Patient(s): 100 premenopausal women with dysfunctional uterine bleeding were observed for 1 year.

Intervention(s): Intrauterine laser thermotherapy with a diode laser.

Main Outcome Measurement(s): Amenorrhea rate after 1 year.

Result(s): The amenorrhea rate after 1 year of follow-up was 71%, and the rate of amenorrhea/severe hypomenorrhea rate was >90%; these rates are much higher than those in the literature after such procedures as electrosurgery or intrauterine thermal balloon therapy. The ELITT procedure is an inherently safe and simple alternative, providing controlled and effective treatment of the entire endometrium. In contrast to traditional endometrial ablation using a neodymium yttrium-aluminum-garnet laser, the ELITT procedure does not require intensive training or hysteroscopic control; it is also far less risky, because the power used per unit area is 1,000 times lower.

Conclusion(s): The ELITT procedure is a new nonhysteroscopic technique for endometrial ablation. The technique is very safe and offers the highest amenorrhea rate to date in the literature.

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