Detection of quantitative trait loci affecting non-return rate in French dairy cattle.

Animals; Cattle/genetics; Chromosome Mapping; Chromosomes, Mammalian; Dairying; Female; Fertility/genetics; France; Genotype; Linkage (Genetics); Microsatellite Repeats; Quantitative Trait Loci

Abstract :

[en] The purpose of this study was to map quantitative trait loci (QTL) influencing female fertility estimated by non-return rate (NRR) in the French dairy cattle breeds Prim'Holstein, Normande and Montbeliarde. The first step was a QTL detection study on NRR at 281 days after artificial insemination on 78 half-sib families including 4993 progeny tested bulls. In Prim'Holstein, three QTL were identified on Bos taurus chromosomes BTA01, BTA02 and BTA03 (p < 0.01), whereas one QTL was identified in Normande on BTA01 (p < 0.05). The second step aimed at confirming these three QTL and refining their location by selecting and genotyping additional microsatellite markers on a sub-sample of 41 families from the three breeds using NRR within 56, 90 and 281 days after AI. Only the three QTL initially detected in Prim'Holstein were confirmed. Moreover, the analysis of NRR within 56, 90 and 281 days after AI allowed us to distinguish two FF QTL on BTA02 in Prim'Holstein, one for NRR56 and one for NRR90. Estimated QTL variance was 18%, 14%, 11.5% and 14% of the total genetic variance, respectively, for QTL mapping to BTA01, BTA02 (NRR90 and NRR56) and BTA03.

Disciplines :

Genetics & genetic processes
Animal production & animal husbandry

Author, co-author :

Ben Jemaa, S.

Fritz, S.

Guillaum, F.

Druet, Tom ; Institut Scientifique de Recherche Agronomique - INRA > Département de Génétique Animale > Station de Génétique Quantitative et Appliquée

Denis, C.

Eggen, A.

Gautier, M.

Language :

English

Title :

Detection of quantitative trait loci affecting non-return rate in French dairy cattle.

Publication date :

2008

Journal title :

Journal of Animal Breeding and Genetics

ISSN :

0931-2668

eISSN :

1439-0388

Publisher :

Blackwell Publishing, Berlin, Germany

Volume :

125

Issue :

Pages :

280-8

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 07 May 2010

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