Reference : Same or different ? An exploration in the behavioral effects of benzamides
Scientific journals : Article
Social & behavioral sciences, psychology : Animal psychology, ethology & psychobiology
Same or different ? An exploration in the behavioral effects of benzamides
Richelle, Marc mailto [Université de Liège - ULiège > Services généraux (Fac. de psycho. et des sc. de l'éducat.) > Relations académiques et scientifiques (Psycho et sc.éduc.) >]
Revista Mexicana de Analisis de la Conducta
[fr] Comportement animal ; Expérimentation ; Psychopharmacologie
[en] Behavioral pharmacology ; Benzamides ; Rats ; Cats
[es] Farmacología conductual ; Benzamidas ; Ratas ; Gatos
[en] Modern research in behavioral pharmacology involves the evaluation of new compounds, searching for similarities with some reference drugs. However, to detect possible unexpected effects, one should look for different rather similar effects, with respect to known drugs. In the present paper, the behavioral effects of two benzamides, namely sulpiride and tiapride, are evaluated, stressing the features that differentiate them from other drugs. Rats ans cats were employed as subjects and performance was maintained by several aversive and positive reinforcement schedules. The benzamides explored do not fit simply into the classificatory frames of present day psychopharmacology, since several differences were evident with respect to the behavioral effects of well known compounds.
[es] La investigación moderna en farmacología conductal involucra la evaluación de nuevos compuestos, buscando semejanzas con algunas drogas de referencia. Sin embargo, para detectar posibles efectos inesperados, se deben buscar efectos diferentes más bien que similares, con respecto a droguas conocidas. En el presente trabajo se evaluaron los efectos conductuales de dos benzamidas, la sulpirida y la tiaprida, enfatizando los rasgos que les diferencían de otras drogas. Se emplearon ratas y gatos como sujetos y se mantuvo la ejecucíon por medio de progamas aversivos y de reforzamiento positivo. Las benzamidas exploradas no se ajustan simplemente a los marcos clasificatorios de la psicofarmacología actual, puesto que varias diferencias fueron evidentes con respecto a los efectos conductuales de compuestos bien conocidos.
Researchers ; Professionals

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