Translocation (2;3)(p21;q26) as the sole anomaly in a case of primary myelofibrosis.

[en] Translocation t(2p;3q) is a rare but recurrent finding in myeloid disorders. We present the first case of primary myelofibrosis with t(2;3)(p21;q26) as the sole chromosomal anomaly. The comparison with the 11 other previously published myeloid-associated t(2p;3q) cases confirms that this nonrandom translocation involves a pluripotent stem cell and is associated with a poor prognosis.

Disciplines :

Hematology
Genetics & genetic processes

Author, co-author :

Herens, Christian ; Centre Hospitalier Universitaire de Liège - CHU > Génétique

Hermanne, Jean-Philippe; Centre Hospitalier Universitaire de Liège - CHU

Tassin, Françoise ; Centre Hospitalier Universitaire de Liège - CHU > Hématologie biologique et immuno hématologie

Fassotte, Marie-France ; Centre Hospitalier Universitaire de Liège - CHU > Hématologie clinique

Thiry, Albert ; Université de Liège - ULiège > Anatomie pathologique

Jamar, Mauricette ; Université de Liège - ULiège > Génétique

Schaaf-Lafontaine, Nicole ; Centre Hospitalier Universitaire de Liège - CHU > Hématologie biologique et immuno hématologie

Fillet, Georges ; Centre Hospitalier Universitaire de Liège - CHU > Hématologie clinique

Koulischer, Lucien ; Université de Liège - ULiège > Relations académiques et scientifiques (Médecine)

Language :

English

Title :

Translocation (2;3)(p21;q26) as the sole anomaly in a case of primary myelofibrosis.

Publication date :

1999

Journal title :

Cancer Genetics and Cytogenetics

ISSN :

0165-4608

eISSN :

1873-4456

Publisher :

Elsevier Science, New York, United States - New York

Volume :

110

Issue :

Pages :

62-4

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 31 March 2009

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Bibliography

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