Profil

Martinez Alvarez Juan Andrés

Département GxABT > Microbial technologies

See author's contact details
ORCID
0000-0002-2331-5369
Main Referenced Co-authors
Delvigne, Frank  (15)
Henrion, Lucas  (9)
Vandenbroucke, Vincent  (8)
Telek, Samuel  (6)
Zicler, Andrew  (4)
Main Referenced Keywords
Biotechnology (3); Recombinant Proteins (3); Recombinant Proteins/metabolism (3); Applied Microbiology and Biotechnology (2); Bioengineering (2);
Main Referenced Disciplines
Biotechnology (11)
Biochemistry, biophysics & molecular biology (4)
Microbiology (2)

Publications (total 17)

The most downloaded
45 downloads
Henrion, L., Martinez Alvarez, J. A., Vandenbroucke, V., Delvenne, M., Telek, S., Zicler, A., Grünberger, A., & Delvigne, F. (02 October 2023). Fitness cost associated with cell phenotypic switching drives population diversification dynamics and controllability. Nature Communications, 14 (1), 6128. doi:10.1038/s41467-023-41917-z https://hdl.handle.net/2268/307892

The most cited

16 citations (OpenAlex)

Bulté, D. B., Palomares, L. A., Parra, C. G., Martinez Alvarez, J. A., Contreras, M. A., Noriega, L. G., & Ramírez, O. T. (September 2020). Overexpression of the mitochondrial pyruvate carrier reduces lactate production and increases recombinant protein productivity in CHO cells. Biotechnology and Bioengineering, 117 (9), 2633 - 2647. doi:10.1002/bit.27439 https://hdl.handle.net/2268/318719

Martinez Alvarez, J. A., Bouchat, R., Gallet de Saint Aurin, T., Martínez, L. M., Caspeta, L., Telek, S., Zicler, A., Gosset, G., & Delvigne, F. (2024). Automated adjustment of metabolic niches enables the control of natural and engineered microbial co-cultures. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/318679. doi:10.1101/2024.05.14.594082

Martinez Alvarez, J. A., Bouchat, R., Gallet de Saint Aurin, T., Vandenbroucke, V., & Delvigne, F. (09 May 2024). Elementary Flux Mode Analysis predicts co-culture stability in continuous bioprocesses [Poster presentation]. 8th BioProScale Symposium 2024, Berlin, Germany.
Editorial reviewed

Tieke, M., Martinez Alvarez, J. A., Henrion, L., & Delvigne, F. (08 March 2024). Assimilation of plastic-derived monomers by P. putida KT2440 in continuous cultures [Poster presentation]. 30th Annual BSM Symposium, Brussel, Belgium.

Henrion, L., Delvigne, F., Martinez Alvarez, J. A., Tieke, M., & Vandenbroucke, V. (08 March 2024). Burdensome gene expression promotes heterogeneity in cellular response that can be mitigated up to a tipping point [Poster presentation]. Belgian society for microbiology, Bruxelles, Belgium.

Henrion, L., Martinez Alvarez, J. A., Vandenbroucke, V., Delvenne, M., Telek, S., Zicler, A., Grünberger, A., & Delvigne, F. (02 October 2023). Fitness cost associated with cell phenotypic switching drives population diversification dynamics and controllability. Nature Communications, 14 (1), 6128. doi:10.1038/s41467-023-41917-z
Peer Reviewed verified by ORBi

Delvigne, F., & Martinez Alvarez, J. A. (October 2023). Advances in automated and reactive flow cytometry for synthetic biotechnology. Current Opinion in Biotechnology, 83, 102974. doi:10.1016/j.copbio.2023.102974
Peer Reviewed verified by ORBi

Tieke, M., Martinez Alvarez, J. A., & Delvigne, F. (19 September 2023). Controlling the phenotypic switching of P. putida population for the assimilation of plastic-derived compounds [Poster presentation]. 6th Microbial Stress 2023 Conference, Vienna, Austria.

Henrion, L., Martinez Alvarez, J. A., Vandenbroucke, V., Delvenne, M., Telek, S., Zicler, A., Grunberger, A., & Delvigne, F. (2023). Fitness cost associated with cell phenotypic switching drives population diversification dynamics and controllability. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/305924. doi:10.1101/2023.04.06.535654

Velastegui, E., Quezada, J., Guerrero, K., Altamirano, C., Martinez Alvarez, J. A., Berrios, J., & Fickers, P. (April 2023). Is heterogeneity in large-scale bioreactors a real problem in recombinant protein synthesis by Pichia pastoris? Applied Microbiology and Biotechnology, 107 (7-8), 2223 - 2233. doi:10.1007/s00253-023-12434-2
Peer Reviewed verified by ORBi

Vandenbroucke, V., Henrion, L., Martinez Alvarez, J. A., & Delvigne, F. (10 February 2023). Managing bacterial growth and phenotypic diversification through the external control of synthetic gene circuits [Poster presentation]. Annual Symposium 2023: Amazing Microbes, Brussels, Belgium.

Delvigne, F., Henrion, L., Vandenbroucke, V., & Martinez Alvarez, J. A. (2023). Avoiding the All-or-None Response in Gene Expression During E. coli Continuous Cultivation Based on the On-Line Monitoring of Cell Phenotypic Switching Dynamics. In Inclusion Bodies Methods and Protocols. Methods in Molecular Biology. doi:10.1007/978-1-0716-2930-7_7
Peer reviewed

Vandenbroucke, V., Henrion, L., Martinez Alvarez, J. A., & Delvigne, F. (07 December 2022). Managing bacterial growth through external control of synthetic gene circuits [Poster presentation]. Emerging Applications of Microbes (2nd edition), Leuven, Belgium.

Martinez Alvarez, J. A., Delvenne, M., Henrion, L., Moreno, F., Telek, S., Dusny, C., & Delvigne, F. (October 2022). Controlling microbial co-culture based on substrate pulsing can lead to stability through differential fitness advantages. PLoS Computational Biology, 18 (10), 1010674. doi:10.1371/journal.pcbi.1010674
Peer Reviewed verified by ORBi

Vandenbroucke, V., Vandenbroucke, V., Henrion, L., Moreno Avitia, F., Delvigne, F., & Martinez Alvarez, J. A. (2022). Enabling continuous co-culture bioprocesses (C3BIO) based on oscillating environmental conditions promoting genetic and/or metabolic requirements of individual species [Paper presentation]. Bioproscale 2022 (https://biotechnologie.ifgb.de/bioproscale2022), Berlin, Germany.

Bajoul Kakahi, F., Martinez Alvarez, J. A., Avitia, F. M., Telek, S., Volke, D. C., Wirth, N. T., Nikel, P. I., & Delvigne, F. (2021). Release of extracellular DNA by<i>Pseudomonas</i>species as a major determinant for biofilm switching and an early indicator for cell population control. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/318675. doi:10.1101/2021.02.11.430776

Nguyen Minh, T., Telek, S., Zicler, A., Martinez Alvarez, J. A., Zacchetti, B., Kopp, J., Slouka, C., Herwig, C., Grünberger, A., & Delvigne, F. (2021). Reducing phenotypic instabilities of a microbial population during continuous cultivation based on cell switching dynamics. Biotechnology and Bioengineering. doi:10.1002/bit.27860
Peer Reviewed verified by ORBi

Bulté, D. B., Palomares, L. A., Parra, C. G., Martinez Alvarez, J. A., Contreras, M. A., Noriega, L. G., & Ramírez, O. T. (September 2020). Overexpression of the mitochondrial pyruvate carrier reduces lactate production and increases recombinant protein productivity in CHO cells. Biotechnology and Bioengineering, 117 (9), 2633 - 2647. doi:10.1002/bit.27439
Peer Reviewed verified by ORBi

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