Profil

Maseko Sibusiso Bonginkhost

GIGA Molecular & Comput. Biol. - Viral Interactomes Network

Département GxABT > Microbial technologies

See author's contact details
ORCID
0000-0001-7025-6106
Main Referenced Co-authors
Twizere, Jean-Claude  (6)
Olivet, Julien  (4)
Blavier, Jeremy  (3)
Vidal, Marc (3)
Calderwood, Michael A (2)
Main Referenced Keywords
Drug Discovery (2); Humans (2); Molecular Medicine (2); Pharmacology (2); AlphaFold (1);
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (4)
Immunology & infectious disease (1)
Life sciences: Multidisciplinary, general & others (1)

Publications (total 6)

The most downloaded
138 downloads
Trepte, P.* , Secker, C.* , Olivet, J.* , Blavier, J.* , Kostova, S., Maseko, S. B., Minia, I., Silva Ramos, E., Cassonnet, P., Golusik, S., Zenkner, M., Beetz, S., Liebich, M. J., Scharek, N., Schütz, A., Sperling, M., Lisurek, M., Wang, Y., Spirohn, K., ... Wanker, E. E.*. (April 2024). AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor. Molecular Systems Biology, 20 (4), 428 - 457. doi:10.1038/s44320-024-00019-8 https://hdl.handle.net/2268/318400

The most cited

45 citations (OpenAlex)

Kim, D.-K., Weller, B., Lin, C.-W., Sheykhkarimli, D., Knapp, J. J., Dugied, G., Zanzoni, A., Pons, C., Tofaute, M. J., Maseko, S. B., Spirohn, K., Laval, F., Lambourne, L., Kishore, N., Rayhan, A., Sauer, M., Young, V., Halder, H., la Rosa, N. M.-D., ... Falter-Braun, P. (10 October 2022). A proteome-scale map of the SARS-CoV-2–human contactome. Nature Biotechnology, 41 (1), 140-149. doi:10.1038/s41587-022-01475-z https://hdl.handle.net/2268/305836

The most significant

Venit, T.* , Blavier, J.* , Maseko, S. B.* , Shu, S., Espada, L., Breunig, C., Holthoff, H.-P., Desbordes, S. C., Lohse, M., Esposito, G., Twizere, J.-C.* , & Percipalle, P.*. (2024). Nanobody against SARS-CoV-2 non-structural protein Nsp9 inhibits viral replication in human airway epithelia. Molecular Therapy: Nucleic Acids, 102304. doi:10.1016/j.omtn.2024.102304
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Trepte, P.* , Secker, C.* , Olivet, J.* , Blavier, J.* , Kostova, S., Maseko, S. B., Minia, I., Silva Ramos, E., Cassonnet, P., Golusik, S., Zenkner, M., Beetz, S., Liebich, M. J., Scharek, N., Schütz, A., Sperling, M., Lisurek, M., Wang, Y., Spirohn, K., ... Wanker, E. E.*. (April 2024). AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor. Molecular Systems Biology, 20 (4), 428 - 457. doi:10.1038/s44320-024-00019-8
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Maseko, S. B., Brammerloo, Y., Van Molle, I., Sogues, A., Martin, C., Gorgulla, C., Plant, E., Olivet, J., Blavier, J., Ntombela, T., Delvigne, F., Arthanari, H., El Hajj, H., Bazarbachi, A., Van Lint, C., Salehi-Ashtiani, K., Remaut, H., Ballet, S., Volkov, A. N., & Twizere, J.-C. (21 July 2023). Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction. Antiviral Research, 217, 105675. doi:10.1016/j.antiviral.2023.105675
Peer Reviewed verified by ORBi

Kim, D.-K., Weller, B., Lin, C.-W., Sheykhkarimli, D., Knapp, J. J., Dugied, G., Zanzoni, A., Pons, C., Tofaute, M. J., Maseko, S. B., Spirohn, K., Laval, F., Lambourne, L., Kishore, N., Rayhan, A., Sauer, M., Young, V., Halder, H., la Rosa, N. M.-D., ... Falter-Braun, P. (10 October 2022). A proteome-scale map of the SARS-CoV-2–human contactome. Nature Biotechnology, 41 (1), 140-149. doi:10.1038/s41587-022-01475-z
Peer Reviewed verified by ORBi

Olivet, J., Maseko, S. B., Volkov, A. N., Salehi-Ashtiani, K., Das, K., Calderwood, M. A., Twizere, J.-C.* , & Gorgulla, C.*. (2022). A systematic approach to identify host targets and rapidly deliver broad-spectrum antivirals. Molecular Therapy. doi:10.1016/j.ymthe.2022.02.015
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.


Venit, T.* , Blavier, J.* , Maseko, S. B.* , Shu, S., Espada, L., Breunig, C., Holthoff, H.-P., Desbordes, S. C., Lohse, M., Esposito, G., Twizere, J.-C.* , & Percipalle, P.*. (2024). Nanobody against SARS-CoV-2 non-structural protein Nsp9 inhibits viral replication in human airway epithelia. Molecular Therapy: Nucleic Acids, 102304. doi:10.1016/j.omtn.2024.102304
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Trepte, P.* , Secker, C.* , Olivet, J.* , Blavier, J.* , Kostova, S., Maseko, S. B., Minia, I., Silva Ramos, E., Cassonnet, P., Golusik, S., Zenkner, M., Beetz, S., Liebich, M. J., Scharek, N., Schütz, A., Sperling, M., Lisurek, M., Wang, Y., Spirohn, K., ... Wanker, E. E.*. (April 2024). AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor. Molecular Systems Biology, 20 (4), 428 - 457. doi:10.1038/s44320-024-00019-8
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Maseko, S. B., Brammerloo, Y., Van Molle, I., Sogues, A., Martin, C., Gorgulla, C., Plant, E., Olivet, J., Blavier, J., Ntombela, T., Delvigne, F., Arthanari, H., El Hajj, H., Bazarbachi, A., Van Lint, C., Salehi-Ashtiani, K., Remaut, H., Ballet, S., Volkov, A. N., & Twizere, J.-C. (21 July 2023). Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction. Antiviral Research, 217, 105675. doi:10.1016/j.antiviral.2023.105675
Peer Reviewed verified by ORBi

Kim, D.-K., Weller, B., Lin, C.-W., Sheykhkarimli, D., Knapp, J. J., Dugied, G., Zanzoni, A., Pons, C., Tofaute, M. J., Maseko, S. B., Spirohn, K., Laval, F., Lambourne, L., Kishore, N., Rayhan, A., Sauer, M., Young, V., Halder, H., la Rosa, N. M.-D., ... Falter-Braun, P. (10 October 2022). A proteome-scale map of the SARS-CoV-2–human contactome. Nature Biotechnology, 41 (1), 140-149. doi:10.1038/s41587-022-01475-z
Peer Reviewed verified by ORBi

Olivet, J., Maseko, S. B., Volkov, A. N., Salehi-Ashtiani, K., Das, K., Calderwood, M. A., Twizere, J.-C.* , & Gorgulla, C.*. (2022). A systematic approach to identify host targets and rapidly deliver broad-spectrum antivirals. Molecular Therapy. doi:10.1016/j.ymthe.2022.02.015
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Vandermeulen, C., O'Grady, T., Wayet, J., Galvan, B., Maseko, S. B., Cherkaoui, M., Desbuleux, A., Coppin, G., Olivet, J., Ben Ameur, L., Kataoka, K., Ogawa, S., Hermine, O., Marcais, A., Thiry, M., Mortreux, F., Calderwood, M. A., Van Weyenbergh, J., Peloponese, J.-M., ... Twizere, J.-C. (2021). The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape. PLoS Pathogens, 17 (9), 1009919. doi:10.1371/journal.ppat.1009919
Peer Reviewed verified by ORBi

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