Davoine, C., Pochet Lionel, & Fillet, M. (31 January 2024). Fragment screening and binding site characterization using affinity capillary electrophoresis in the context of drug discovery [Paper presentation]. CIRM Day, Liege, Belgium. |
  | Davoine, C., Traina, A., Evrard, J., Lanners, S., Fillet, M., & Pochet, L. (05 November 2023). Coumarins as factor XIIa inhibitors: Potency and selectivity improvements using a fragment-based strategy. European Journal of Medicinal Chemistry, 259, 115636. doi:10.1016/j.ejmech.2023.115636  Peer Reviewed verified by ORBi |
Davoine, C., Pochet, L., & Fillet, M. (27 October 2023). Activity and affinity assays by capillary electrophoresis in the context of drug screening [Paper presentation]. Jinan University, Guangzhou, China. Peer reviewed |
Davoine, C., Pochet, L., & Fillet, M. (28 September 2023). Intérêt de l’EC dans le contexte du développement de médicaments pour le screening de ligands et la caractérisation de leur interaction avec la cible thérapeutique [Paper presentation]. Conférence « La Chimie Analytique au service de la Santé », Geneve, Switzerland. Peer reviewed |
 | Davoine, C., Pochet, L., & Fillet, M. (September 2023). Advances in analytical technologies detecting and characterizing noncovalent interactions for fragment-based drug discovery. TrAC: Trends in Analytical Chemistry, 166, 117161. doi:10.1016/j.trac.2023.117161 Peer Reviewed verified by ORBi |
 | Davoine, C. (2023). Identification, characterization, and optimization of fragment hits against coagulation factor XIIa supported by affinity capillary electrophoresis and biochemical assay [Doctoral thesis, UNamur - Université de Namur]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/302278 |
Davoine, C., Pochet, L., & Fillet, M. (11 September 2022). Affinity Capillary Electrophoresis for Fragment-based Drug Discovery Projects: Hit Discovery and Binding Site Characterization [Paper presentation]. 12th International Symposium on Drug Analysis and the 32nd International Symposium on Pharmaceutical and Biomedical Analysis (DA-PBA 2022), Mons, Belgium. Peer reviewed |
Davoine, C., Pochet Lionel, & Fillet, M. (03 July 2022). Capillary Electrophoresis in Fragment-based Drug Discovery Projects, A tool for Hit discovery and Binding site Characterization [Paper presentation]. 38th International Symposium on Microscale Separations and Bioanalysis (MSB 2022), Liege, Belgium. Peer reviewed |
Davoine, C., Pochet, L., & Fillet, M. (03 July 2022). Affinity Capillary Electrophoresis in Fragment-based Drug Discovery Projects, A tool for Hit discovery and Binding site Characterization [Paper presentation]. 38th International Symposium on Microscale Separations and Bioanalysis (MSB 2022), Liège, Belgium. Peer reviewed |
Davoine, C., Fillet, M., & Pochet, L. (19 May 2022). Discovery of Potent FXIIa Inhibitors using a Fragment-based Strategy [Paper presentation]. FNRS Med Chem Meeting, Namur, Belgium. |
Davoine, C., Pochet, L., & Fillet, M. (02 February 2022). Development of Factor XIIa Inhibitors Assisted by Affinity Capillary Electrophoresis, A Fragment-based Lead Discovery Project [Paper presentation]. CIRM day 2022, Liège, Belgium. Peer reviewed |
  | Davoine, C., Pardo, A., Pochet, L., & Fillet, M. (09 November 2021). Fragment Hit Discovery and Binding Site Characterization by Indirect Affinity Capillary Electrophoresis: Application to Factor XIIa. Analytical Chemistry, 93, 14802–14809. doi:10.1021/acs.analchem.1c03611 Peer Reviewed verified by ORBi |
Davoine, C., Simon, F., Bouckaert, C., Fillet, M., & Pochet, L. (09 September 2021). Using Biochemical Assay and Capillary Electrophoresis to Explore Fragments against Coagulation Factor XIIa [Poster presentation]. 8th EFMC Young Medicinal Chemists' Symposium. Peer reviewed |
Davoine, C., Simon, F., Lanners, S., Fillet, M., & Pochet, L. (28 May 2021). Exploring Fragments to Design FXIIa Inhibitors with Biochemical Assay and Capillary Electrophoresis [Paper presentation]. FNRS Med Chem Meeting. |
 | Davoine, C., Fillet, M., & Pochet, L. (26 May 2021). Uncovering biochemical assay’s false positives by counter-screening a fragment library with affinity capillary electrophoresis [Poster presentation]. CIRM-day 2021. |
 | Davoine, C., Fillet, M., & Pochet, L. (01 May 2021). Capillary electrophoresis as a fragment screening tool to cross-validate hits from chromogenic assay: Application to FXIIa. Talanta, 226. doi:10.1016/j.talanta.2021.122163 Peer Reviewed verified by ORBi |
 | Davoine, C., Bouckaert, C., Fillet, M., & Pochet, L. (15 December 2020). Factor XII/XIIa inhibitors: Their discovery, development, and potential indications. European Journal of Medicinal Chemistry, 208. doi:10.1016/j.ejmech.2020.112753 Peer Reviewed verified by ORBi |
Davoine, C., Simon, F., Bouckaert, C., Lanners, S., Fillet, M., & Pochet, L. (January 2020). Using fragment-based lead discovery to generate new scaffolds for the development of FXIIa inhibitors [Poster presentation]. 2nd Alpine Winter Conference on Medicinal and Synthetic Chemistry, St. Anton, Austria. |
Davoine, C., Farcas, E., Bouckaert, C., Pochet, L., & Fillet, M. (11 December 2019). Flow-through partial-filling affinity capillary electrophoresis for the detection of weak ligand-target interactions: application to coagulation factor XIIa [Poster presentation]. CIRM-day 2019, Liège, Belgium. |
  | Gils, M., Ledoux, A., Davoine, C., Desdemoustier, P., Clain, M.-E., Castillo Cabello, G., Frederich, M., & Fillet, M. (11 December 2019). Affinity capillary electrophoresis as a tool for the discovery of new antimalarial natural compounds [Poster presentation]. 2nd CIRM Scientific Day. |
Davoine, C., Farcas, E., Simon, F., Bouckaert, C., Lanners, S., Pochet, L., & Fillet, M. (22 November 2019). Affinity capillary electrophoresis as a powerful tool for fragment-based screening: application to the inhibition of S1A serine proteases implicated in the coagulation cascade [Poster presentation]. Annual One-Day Meeting on Medicinal Chemistry of KVCV & SRC - MedChem2019, Brussels, Belgium. Peer reviewed |
Davoine, C., Farcas, E., Thabault, L., Simon, F., Bouckaert, C., Frédérick, R., Lanners, S., Pochet, L., & Fillet, M. (24 March 2019). Capillary electrophoresis and microscale thermophoresis in fragment-based drug discovery : development of screening bioassays towards FXIIa [Poster presentation]. 7th RSC-BMCS Fragment-based Drug Discovery meeting (Fragment 2019), Cambridge, United Kingdom. Peer reviewed |
Davoine, C., Farcas, E., Bouckaert, C., Pochet, L., & Fillet, M. (19 December 2018). Development of fragments screening bioassays towards thrombin and FXIIa using capillary electrophoresis [Poster presentation]. CIRM-day, Liège, Belgium. |
Davoine, C., Farcas, E., Bouckaert, C., Pochet, L., & Fillet, M. (23 November 2018). Development of capillary electrophoresis bioassays for the screening of fragments : application to thrombin and FXIIa [Poster presentation]. Annual One-Day Symposium on Medicinal Chemistry of SRC & KVCV (Medchem 2018), Namur, Belgium. Peer reviewed |