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Farcas Elena

Main Referenced Co-authors
Fillet, Marianne  (29)
Servais, Anne-Catherine  (21)
Pochet, Lionel (19)
Bouckaert, Charlotte (9)
Crommen, Jacques  (9)
Main Referenced Keywords
Capillary electrophoresis (5); EMMA (5); coagulation factor XIIa (FXIIa) (4); CYP1A1 (4); affinity capillary electrophoresis (ACE) (3);
Main Referenced Unit & Research Centers
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (30)
NAmur Research Institute for Life - NARILIS (3)
NARILIS - NAmur Research Institute for LIfe Sciences (1)
NAmur Research Institute for LIfe Sciences - NARILIS (1)
Main Referenced Disciplines
Pharmacy, pharmacology & toxicology (28)
Biochemistry, biophysics & molecular biology (3)
Chemistry (3)
Biotechnology (1)

Publications (total 30)

The most downloaded
8 downloads
Servais, A.-C., Moldovan, R.-C., Farcas, E., ROLAND, I., & Fillet, M. (June 2013). DEVELOPMENT AND VALIDATION OF A LC METHOD FOR THE STABILITY STUDY OF A PHARMACEUTICAL FORMULATION CONTAINING VORICONAZOLE USING CELLULOSE TRIS(4-CHLORO-3-METHYLPHENYLCARBAMATE) AS CHIRAL SELECTOR AND POLAR NON-AQUEOUS MOBILE PHASE [Poster presentation]. 39th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Amsterdam, Netherlands. https://hdl.handle.net/2268/155075

The most cited

32 citations (OpenAlex)

Dossou, K. S. S., Farcas, E., Servais, A.-C., CHIAP, P., Chankvetadze, B., Crommen, J., & Fillet, M. (2012). Optimization of the liquid chromatography enantioseparation of chiral acidic compounds using cellulose tris(3-chloro-4-methylphenylcarbamate) as chiral selector and polar organic mobile phases. Journal of Chromatography. A, 1234, 56-63. doi:10.1016/j.chroma.2012.01.072 https://hdl.handle.net/2268/127588

Davoine, C., Farcas, E., Bouckaert, C., Pochet, L., & Fillet, M. (11 December 2019). Flow-through partial-filling affinity capillary electrophoresis for the detection of weak ligand-target interactions: application to coagulation factor XIIa [Poster presentation]. CIRM-day 2019, Liège, Belgium.

Davoine, C., Farcas, E., Simon, F., Bouckaert, C., Lanners, S., Pochet, L., & Fillet, M. (22 November 2019). Affinity capillary electrophoresis as a powerful tool for fragment-based screening: application to the inhibition of S1A serine proteases implicated in the coagulation cascade [Poster presentation]. Annual One-Day Meeting on Medicinal Chemistry of KVCV & SRC - MedChem2019, Brussels, Belgium.
Peer reviewed

Davoine, C., Farcas, E., Thabault, L., Simon, F., Bouckaert, C., Frédérick, R., Lanners, S., Pochet, L., & Fillet, M. (24 March 2019). Capillary electrophoresis and microscale thermophoresis in fragment-based drug discovery : development of screening bioassays towards FXIIa [Poster presentation]. 7th RSC-BMCS Fragment-based Drug Discovery meeting (Fragment 2019), Cambridge, United Kingdom.
Peer reviewed

Davoine, C., Farcas, E., Bouckaert, C., Pochet, L., & Fillet, M. (19 December 2018). Development of fragments screening bioassays towards thrombin and FXIIa using capillary electrophoresis [Poster presentation]. CIRM-day, Liège, Belgium.

Davoine, C., Farcas, E., Bouckaert, C., Pochet, L., & Fillet, M. (23 November 2018). Development of capillary electrophoresis bioassays for the screening of fragments : application to thrombin and FXIIa [Poster presentation]. Annual One-Day Symposium on Medicinal Chemistry of SRC & KVCV (Medchem 2018), Namur, Belgium.
Peer reviewed

Nys, G., COBRAIVILLE, G., Farcas, E., Demelenne, A., Kok, M., Servais, A.-C., & Fillet, M. (October 2018). Microfluidic analytical approaches to drive drug development [Paper presentation]. In the framework of High-end Foreign Experts program, Guangzhou, China.

Farcas, E., Servais, A.-C., Hanson, J., Pochet, L., & Fillet, M. (10 September 2018). Partial filling capillary electrophoretic mobility shift competition assay: a versatile and reliable tool for the assessment of weak biomolecular interactions [Paper presentation]. The 11th International Symposium on Drug Analysis and the 29th International Symposium on Pharmaceutical and Biomedical Analysis, Leuven, Belgium.

Farcas, E., Servais, A.-C., Crommen, J., Pochet, L., & Fillet, M. (July 2018). Electrodriven methodologies for the screening of new antithrombotic drugs [Paper presentation]. 2nd International Symposium on Advances in Pharmaceutical Analysis (APA 2018), Lille, France.

Farcas, E., Pochet, L., & Fillet, M. (June 2018). Transverse diffusion of laminar flow profiles as a generic capillary electrophoresis method for in-line nanoreactor mixing: application to the investigation of antithrombotic activity. Talanta, 188, 516-521. doi:10.1016/j.talanta.2018.06.014
Peer Reviewed verified by ORBi

Farcas, E. (2018). Contribution of capillary electrophoresis at the early stage of drug discovery [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/224143

Farcas, E., Hanson, J., Pochet, L., & Fillet, M. (2018). Capillary electrophoretic mobility shift displacement assay for the assessment of weak drug-protein interactions. Analytica Chimica Acta. doi:10.1016/j.aca.2018.06.024
Peer Reviewed verified by ORBi

Farcas, E., Servais, A.-C., Bouckaert, C., Crommen, J., Pochet, L., & Fillet, M. (13 September 2017). Partial filling affinity capillary electrophoresis as a useful tool for fragment-based drug discovery: A proof of concept on thrombin [Paper presentation]. EDT PhD day, Spa, Belgium.

Farcas, E., Bouckaert, C., Servais, A.-C., Crommen, J., Pochet, L., & Fillet, M. (20 June 2017). Optimization of an electrophoretic approach for the screening and the development of new antithrombotic drugs [Paper presentation]. The 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Prague, Czechia.

Farcas, E., Bouckaert, C., Servais, A.-C., Crommen, J., Pochet, L., & Fillet, M. (19 June 2017). Optimiaztion of an electrophoretic approach for the screening and the development of new antithrombotic drugs [Poster presentation]. The 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Prague, Czechia.

Farcas, E., Bouckaert, C., Servais, A.-C., Hanson, J., Pochet, L., & Fillet, M. (2017). Partial filling affinity capillary electrophoresis as a useful tool for fragment-based drug discovery: A proof of concept on thrombin. Analytica Chimica Acta, 984, 211-222. doi:10.1016/j.aca.2017.06.035
Peer Reviewed verified by ORBi

Farcas, E., Pochet, L., Crommen, J., Servais, A.-C., & Fillet, M. (2017). Capillary electrophoresis in the context of drug discovery. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2017.02.022
Peer Reviewed verified by ORBi

Farcas, E., Servais, A.-C., Lamalle, C., CHIAP, P., Pochet, L., & Fillet, M. (01 October 2016). OPTIMIZATION OF A FULLY AUTOMATED ELECTROPHORETICALLY MEDIATED MICROANALYSIS SYSTEM FOR CYP1A1 ACTIVITY MONITORING [Paper presentation]. The 16th Edition of National Congress of Pharmacy in Romania, Bucharest, Romania.

Furst, T., Bettonville, V., Farcas, E., Frère, A., Lechanteur, A., Evrard, B., Fillet, M., Piel, G., & Servais, A.-C. (2016). Capillary electrophoresis method to determine siRNA complexation with cationic liposomes. Electrophoresis. doi:10.1002/elps.201600249
Peer Reviewed verified by ORBi

Farcas, E., Servais, A.-C., Lamalle, C., CHIAP, P., Pochet, L., & Fillet, M. (2016). Fully automated electrophoretically mediated microanalysis for CYP1A1 activity monitoring optimized by multivariate approach. Electrophoresis, 37 (2), 248-255. doi:10.1002/elps.201500214
Peer Reviewed verified by ORBi

Farcas, E., Servais, A.-C., Lamalle, C., Chiap, P., Pochet, L., & Fillet, M. (08 September 2015). OPTIMIZATION OF A FULLY AUTOMATED ELECTROPHORETICALLY MEDIATED MICROANALYSIS SYSTEM FOR CYP1A1 ACTIVITY MONITORING [Poster presentation]. UniGR workshop: From drug target to drug development.

Farcas, E., Servais, A.-C., Lamalle, C., Chiap, P., Pochet, L., & Fillet, M. (23 June 2015). FULLY AUTOMATED ELECTROPHORETICALLY MEDIATED MICROANALYSIS SYSTEM FOR CYP1A1 ACTIVITY MONITORING [Poster presentation]. HPLC 2015, Geneva, Switzerland.

Farcas, E., Servais, A.-C., Lamalle, C., Chiap, P., Pochet, L., & Fillet, M. (28 May 2015). Fully automated electrophoretically mediated microanalysis system for CYP1A1 activity monitoring [Paper presentation]. THE 18th FORUM OF PHARMACEUTICAL SCIENCES, Blankenberge, Belgium.

Farcas, E., Servais, A.-C., Lamalle, C., CHIAP, P., & Fillet, M. (22 June 2014). DEVELOPMENT OF AN ELECTROPHORETICALLY MEDIATED MICROANALYSIS FOR THE IN-LINE METABOLISM STUDY OF 7-ETHOXYCOUMARIN [Poster presentation]. 10th International Symposium on Drug Analysis - 25th International Symposium on Pharmaceutical and Biomedical Analysis, Liege, Belgium.

Farcas, E., & Fillet, M. (20 January 2014). Thrombosis prevention without bleeding: myth or reality? Development of selective inhibitors of FXIIa [Paper presentation]. Forum des jeunes chercheurs, Liege, Belgium.

Servais, A.-C., Moldovan, R.-C., Farcas, E., Crommen, J., ROLAND, I., & Fillet, M. (2014). Development and validation of a liquid chromatographic method for the stability study of a pharmaceutical formulation containing voriconazole using cellulose tris(4-chloro-3-methylphenylcarbamate) as chiral selector and polar organic mobile phases. Journal of Chromatography. A, 1363, 178-82. doi:10.1016/j.chroma.2014.06.082
Peer Reviewed verified by ORBi

Fradi, I., Farcas, E., Said, A. B., Yans, M.-L., Lamalle, C., Somsen, G. W., Prior, A., de Jong, G. J., Kallel, M., Crommen, J., Servais, A.-C.* , & Fillet, M.*. (2014). In-capillary derivatization with (-)-1-(9-fluorenyl)ethyl chloroformate as chiral labeling agent for the electrophoretic separation of amino acids. Journal of Chromatography. A, 1363, 338-47. doi:10.1016/j.chroma.2014.07.022
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Servais, A.-C., Moldovan, R.-C., Farcas, E., ROLAND, I., & Fillet, M. (June 2013). DEVELOPMENT AND VALIDATION OF A LC METHOD FOR THE STABILITY STUDY OF A PHARMACEUTICAL FORMULATION CONTAINING VORICONAZOLE USING CELLULOSE TRIS(4-CHLORO-3-METHYLPHENYLCARBAMATE) AS CHIRAL SELECTOR AND POLAR NON-AQUEOUS MOBILE PHASE [Poster presentation]. 39th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Amsterdam, Netherlands.

Pochet, L.* , Servais, A.-C.* , Farcas, E., Bettonville, V., Bouckaert, C., & Fillet, M. (2013). Determination of inhibitory potency of argatroban toward thrombin by electrophoretically mediated microanalysis. Talanta, 116, 719-725. doi:10.1016/j.talanta.2013.07.030
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Dossou, K. S. S., Farcas, E., Servais, A.-C., CHIAP, P., Chankvetadze, B., Crommen, J., & Fillet, M. (2012). Optimization of the liquid chromatography enantioseparation of chiral acidic compounds using cellulose tris(3-chloro-4-methylphenylcarbamate) as chiral selector and polar organic mobile phases. Journal of Chromatography. A, 1234, 56-63. doi:10.1016/j.chroma.2012.01.072
Peer Reviewed verified by ORBi

Crommen, J., Dossou, K. S. S., Farcas, E., Servais, A.-C., & Fillet, M. (2012). HPLC separation and determination of drug enantiomers using chlorine-containing cellulose-based chiral stationary phases and polar organic mobiles phases [Paper presentation]. 10th Annual Congress of International Drug Discovery Science and Technology (IDDST), Nanjing, Jiangsu, China.

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