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![]() ![]() | Moermans, C.* , Schleich, F.* , Gerday, S., Bricmont, N., Bonhiver, R., Graff, S., ZIANT, S., REGNIER, F., Onssels, A., Njock, M.-S., Rosu, A., Henket, M., SANCHEZ, C., PAULUS, V., GUISSARD, F., & Louis, R. (May 2025). The success rate and safety of induced sputum is better than you think: give it a try! ERJ Open Research, 11 (3), 00871-2024. doi:10.1183/23120541.00871-2024 ![]() * These authors have contributed equally to this work. |
![]() ![]() | Massenet, T., Bosman, P., GUISSARD, F., Henket, M., Guiot, J., Schleich, F., Vial, J., Focant, J.-F., & Stefanuto, P.-H. (04 February 2025). Breath Sampling and Patient Considerations for Clinical Implementation: A Comparative Study [Poster presentation]. The Multidimensional Chromatography Workshop (MDCW). |
![]() ![]() | Graff, S., Moermans, C., Gerday, S., Henket, M., PAULUS, V., GUISSARD, F., Louis, R., & Schleich, F. (30 November 2024). Increase in Blood Eosinophil Count Over Time and Sputum IL8 are Associated with FEV1 Decline in Asthma. Lung, 203 (1), 8. doi:10.1007/s00408-024-00760-9 ![]() |
![]() ![]() | Massenet, T., Potjewijd, J., Tobal, R., GESTER, F., Zanella, D., Henket, M., Njock, M.-S., Dejong, T., Gridelet, G., GILTAY, L., GUISSARD, F., André, B., Ribbens, C., Louis, R., Van Paassen, P., Guiot, J., & Stefanuto, P.-H. (November 2024). Systemic Sclerosis: Can Breathomics help clinicians for ILD management? [Poster presentation]. Breath Biopsy Conference 2024. |
![]() ![]() | Sabbe, M., Vervier, J., GUISSARD, F., PAULUS, V., SANCHEZ, C., Bougard, N., Frix, A.-N., Schleich, F., & Louis, R. (2024). Relationship between T2 biomarkers and clinical remission in severe T2 high asthmatics after 12 months of treatment with omalizumab, mepolizumab and benralizumab. European Respiratory Journal 64(suppl 68): PA4815 Published: Sep 2024, 4815. doi:10.1183/13993003.congress-2024.pa4815 |
![]() ![]() | Massenet, T., Patjewijd, J., Tobal, R., GESTER, F., Zanella, D., Henket, M., Njock, M.-S., Dejong, T., Gridelet, G., GILTAY, L., GUISSARD, F., André, B., Ribbens, C., Louis, R., Van Paassen, P., Guiot, J.* , & Stefanuto, P.-H.*. (08 September 2024). SYSTEMIC SCLEROSIS: CAN BREATHOMICS MONITOR INTERSTITIAL LUNG DISEASE? [Poster presentation]. The ERS Congress, Vienne, Austria. * These authors have contributed equally to this work. |
![]() ![]() | Massenet, T., Potjewijd, J., Tobal, R., GESTER, F., Zanella, D., Henket, M., Njock, M.-S., Dejong, T., Gridelet, G., GILTAY, L., GUISSARD, F., André, B., Ribbens, C., Louis, R., Van Paassen, P., Focant, J.-F., Guiot, J., & Stefanuto, P.-H. (28 May 2024). Tackling the analytical challenges to establish a routine workflow for breathomics research [Paper presentation]. 18th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-18), Leuven, Belgium. |
![]() ![]() | Massenet, T., Potjewijd, J., Tobal, R., GESTER, F., Zanella, D., Henket, M., Njock, M.-S., Dejong, T., Gridelet, G., GILTAY, L., GUISSARD, F., André, B., Ribbens, C., Louis, R., Van Paassen, P., Guiot, J., & Stefanuto, P.-H. (2024). Breathomics to monitor interstitial lung disease associated with systemic sclerosis. ERJ Open Research, 00175-2024. doi:10.1183/23120541.00175-2024 ![]() |
![]() ![]() | Zahraei, H. N., Schleich, F., Louis, G., Gerday, S., SABBE, M., Bougard, N., GUISSARD, F., PAULUS, V., Henket, M., Pétré, B., Donneau, A.-F., & Louis, R. (2024). Evidence for two clusters among non-eosinophilic asthmatics. Annals of Allergy, Asthma and Immunology. doi:10.1016/j.anai.2024.03.012 ![]() |
![]() ![]() | Louis, F., PAULUS, V., GUISSARD, F., Philippe, G., Louis, R., & Schleich, F. (2024). Overuse of Short Acting Beta-2 Agonist (SABA) in asthmatics: relationship with lung function and airway inflammation [Poster presentation]. Eurepean Respiratory Society (ERS), Vienne, Austria. |
![]() ![]() | Schleich, F., Moermans, C., Seidel, L., Kempeneers, C., Louis, G., ROGISTER, F., Tombu, S., Pottier, L., Poirrier, A.-L., ZIANT, S., Henket, M., SANCHEZ, C., PAULUS, V., GUISSARD, F., Donneau, A.-F., & Louis, R. (November 2023). Benralizumab in severe eosinophilic asthma in real life: confirmed effectiveness and contrasted effect on sputum eosinophilia versus exhaled nitric oxide fraction - PROMISE. ERJ Open Research, 9 (6). doi:10.1183/23120541.00383-2023 ![]() |
![]() ![]() | Schleich, F., Moermans, C., Gerday, S., ZIANT, S., Louis, G., Bougard, N., PAULUS, V., GUISSARD, F., Henket, M., Bachert, C., & Louis, R. (October 2023). Patients With Asthma Only Sensitized to Staphylococcus aureus Enterotoxins Have More Exacerbations, Airflow Limitation, and Higher Levels of Sputum IL-5 and IgE. Journal of Allergy and Clinical Immunology: In Practice, 11 (10), 3055-3061.e4. doi:10.1016/j.jaip.2023.05.043 ![]() |
![]() ![]() | Sabbe, M., Schleich, F., Bougard, N., Moermans, C., Henquet, M., GUISSARD, F., Sanschez, C., PAULUS, V., & Louis, R. (2023). Sputum cell counts and FeNO levels in patients treated with anti-IgE and anti-IL-5 /IL-5R: Evidence for a dissociation between sputum eosinophil counts and FeNO levels. European Respiratory Journal 62(suppl 67): PA989 Published: Sep 2023, 989. doi:10.1183/13993003.congress-2023.pa989 ![]() |
![]() ![]() | Kempeneers, C., Bonhiver, R., Bricmont, N., Pirotte, M., Engelskirchen, S., Benchimol, L., CALMES, D., GUISSARD, F., Moermans, C., Seghaye, M.-C., Louis, R., & Schleich, F. (September 2023). Ciliary dyskinesia in severe asthma is not affected by chronic mucus hypersecretion. ERJ Open Research, 9 (5). doi:10.1183/23120541.00220-2023 ![]() |
![]() ![]() | Gerday, S., Graff, S., Moermans, C., GUISSARD, F., PAULUS, V., Henket, M., Louis, R., & Schleich, F. (2023). Super-responders to anti-IL-5/anti-IL-5R are characterised by high sputum eosinophil counts at baseline. Thorax, 2022-219781. doi:10.1136/thorax-2022-219781 ![]() |
![]() ![]() | Massenet, T., Potjewijd, J., Henket, M., Gridelet, G., Zanella, D., Dejong, T., GILTAY, L., GESTER, F., GUISSARD, F., André, B., Ribbens, C., Van Paassen, P., Louis, R., Focant, J.-F., Guiot, J.* , & Stefanuto, P.-H.*. (20 June 2023). Breath analysis to diagnose and assess systemic sclerosis using thermal desorption and comprehensive two-dimensional gas chromatography high-resolution time-of-flight mass spectrometry [Poster presentation]. Metabolomics 2023, Niagara Falls, Canada. * These authors have contributed equally to this work. |
![]() ![]() | Zahraei, H. N., Schleich, F., Gerday, S., GUISSARD, F., PAULUS, V., Henket, M., Moermans, C., Donneau, A.-F.* , & Louis, R.*. (June 2023). A clustering analysis of eosinophilic asthmatics: Two clusters with sharp differences in atopic status and disease severity. Clinical and Experimental Allergy, 53 (6), 672-678. doi:10.1111/cea.14312 ![]() * These authors have contributed equally to this work. |
![]() ![]() | Massenet, T., Guiot, J., Zanella, D., Dejong, T., GILTAY, L., Henket, M., GUISSARD, F., André, B., Malaise, M., Potjewijd Judith, Schleich, F., Louis, R., Focant, J.-F., & Stefanuto, P.-H. (29 March 2023). Etude métabolomique de l’air exhalé pour diagnostiquer la sclérodermie systémique par chromatographie gazeuse bidimensionnelle exhaustive [Paper presentation]. SEP 23, Paris, France. |
![]() ![]() | Moermans, C., Brion, C., BOCK, G., Graff, S., Gerday, S., Nekoee, H., Poulet, C., Bricmont, N., Henket, M., PAULUS, V., GUISSARD, F., Louis, R., & Schleich, F. (2023). Sputum Type 2 Markers Could Predict Remission in Severe Asthma Treated With Anti-IL-5. CHEST. doi:10.1016/j.chest.2023.01.037 ![]() |
![]() ![]() | Louis, G., Pétré, B., Schleich, F., Zahrei, H. N., Donneau, A.-F., Henket, M., PAULUS, V., GUISSARD, F., Guillaume, M., & Louis, R. (2023). Predictors of change in asthma-related quality of life: a longitudinal real-life study in adult asthmatics. Quality of Life Research. doi:10.1007/s11136-022-03339-0 ![]() |
![]() ![]() | Louis, G., Schleich, F., Guillaume, M., Kirkove, D., Zahrei, H., Donneau, A.-F., Henket, M., PAULUS, V., GUISSARD, F., Louis, R., & Pétré, B. (2023). Development and validation of a predictive model combining patient-reported outcome measures, spirometry and exhaled nitric oxide fraction for asthma diagnosis. ERJ Open Research, 00451-2022. doi:10.1183/23120541.00451-2022 ![]() |
Stefanuto, P.-H., Zanella, D., Dejong, T., Massenet, T., Di giovanni, N., GILTAY, L., Henket, M., GUISSARD, F., Schleich, F., Guiot, J., André, B., Malaise, M., Potjewijd, J., Meuwis, M.-A., Louis, E., Louis, R., & Focant, J.-F. (2023). A Journey over Current Usage of GC×GC -TOFMS in Metabolomic [Paper presentation]. GCxGC & GCTOF metabonomics Webinar. |
![]() ![]() | Kempeneers, C., Bonhiver, R., Bricmont, N., Pirotte, M., GUISSARD, F., Moermans, C., Seghaye, M.-C., Louis, R., & Schleich, F. (04 September 2022). A primary ciliary dysfunction might be present in severe asthma [Paper presentation]. ERS International Congress, Barcelone, Spain. ![]() |
![]() ![]() | Gerday, S., SCHLEICH, F., Henket, M., GUISSARD, F., PAULUS, V., & LOUIS, R. (01 June 2022). Revisiting differences between atopic and non-atopic asthmatics: When age is shaping airway inflammatory profile. World Allergy Organization Journal, 15 (6), 100655. doi:10.1016/j.waojou.2022.100655 ![]() |
![]() ![]() | Massenet, T., GUIOT, J., Zanella, D., Dejong, T., GILTAY, L., HENKET, M., GUISSARD, F., ANDRE, B., MALAISE, M., Judith Potjewijd, SCHLEICH, F., LOUIS, R., Focant, J.-F., & Stefanuto, P.-H. (18 May 2022). BREATHOMICS APPROACH TO INVESTIGATE SYSTEMIC SCLEROSIS USING THERMAL DESORPTION AND COMPREHENSIVE TWO-DIMENSIONAL GAS CHROMATOGRAPHY HIGH-RESOLUTION TIME-OF-FLIGHT MASS SPECTROMETRY [Poster presentation]. 17th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-17), Gand, Belgium. |
KEMPENEERS, C., Bricmont, N., Bonhiver, R., Pirotte, M., GUISSARD, F., MOERMANS, C., SEGHAYE, M.-C., LOUIS, R., & SCHLEICH, F. (18 May 2022). Ciliary dyskinesia is increased in severe asthma, but is not affected by chronic mucus hypersecretion [Poster presentation]. Congress of American Thoracic Society, San Francisco, United States - California. ![]() |
Gerday, S., Henket, M., GUISSARD, F., PAULUS, V., Louis, R., & Schleich, F. (17 May 2022). Super responders to mepolizumab are characterized by high sputum eosinophils and FeNO at baseline [Poster presentation]. ATS International Conference, San Francisco, United States. |
Nekoee Zahraei, H., SCHLEICH, F., HENKET, M., PAULUS, V., Gerday, S., GUISSARD, F., Donneau, A.-F., & LOUIS, R. (15 May 2022). A clustering analysis of eosinophilic asthmatics [Paper presentation]. The American Thoracic Society International Conference ATS, San Francisco, United States - California. ![]() |
![]() ![]() | Louis, G., Pétré, B., SCHLEICH, F., Nekoee Zahraei, H., Donneau, A.-F., HENKET, M., PAULUS, V., GUISSARD, F., Guillaume, M., & LOUIS, R. (2022). A Real Life Longitudinal Study on Asthma-Related Quality of Life in a Secondary Care Center. American Journal of Respiratory and Critical Care Medicine. doi:10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1334 ![]() |
![]() ![]() | Stefanuto, P.-H., Zanella, D., Dejong, T., Massenet, T., DiGiovanni, N., GILTAY, L., HENKET, M., GUISSARD, F., SCHLEICH, F., GUIOT, J., ANDRE, B., MALAISE, M., Potjewijd, J., MEUWIS, M.-A., LOUIS, E., & Focant, J.-F. (May 2022). Recent advances in medical applications of GC×GC [Paper presentation]. HTC-17, Ghent, Belgium. ![]() |
![]() ![]() | Schleich, F., Graff, S., Bougard, N., Frix, A.-N., Peerboom, S., Demarche, S., GUISSARD, F., PAULUS, V., Henket, M., CALMES, D., Moermans, C., & Louis, R. (May 2022). L’asthme bronchique en pratique clinique : des phénotypes inflammatoires au traitement personnalisé. Revue Médicale de Liège, 77 (5-6), 289-294. ![]() |
KEMPENEERS, C., Bricmont, N., Bonhiver, R., GUISSARD, F., HOUGRAND, O., DELVENNE, P., JACQUINET, A., HARVENGT, J., DOCAMPO MARTINEZ, E., BOURS, V., Benchimol, L., POIRRIER, A.-L., LEFEBVRE, P., CALMES, D., LOUIS, R., & SEGHAYE, M.-C. (17 March 2022). Ciliary videomicroscopy at room temperature lacks sensitivity for PCD diagnosis [Poster presentation]. Congress of the BVK-SBP, Brussels, Belgium. ![]() |
![]() ![]() | Massenet, T., GUIOT, J., Zanella, D., Dejong, T., GILTAY, L., HENKET, M., GUISSARD, F., ANDRE, B., MALAISE, M., Potjewijd Judith, SCHLEICH, F., LOUIS, R., Focant, J.-F., & Stefanuto, P.-H. (01 February 2022). TD-GC×GC-HRTOFMS to investigate pulmonary fibrosis in patients [Poster presentation]. Multidimensional Chromatography Worshop 2022. |
Focant, J.-F., Stefanuto, P.-H., Zanella, D., Dejong, T., Massenet, T., Di Giovanni, N., GILTAY, L., Henket, M., GUISSARD, F., Schleich, F., Guiot, J., André, B., Malaise, M., Potjewijd, J., Meuwis, M.-A., Louis, E., & Louis, R. (2022). Exploring Volatolomes with GC×GC-TOFMS [Paper presentation]. Analytics Nantes 2022, Nantes, France. ![]() |
![]() ![]() | Louis, G., SCHLEICH, F., Guillaume, M., Donneau, A.-F., Nekoee Zahraei, H., HENKET, M., PAULUS, V., GUISSARD, F., Louis, R., & Pétré, B. (05 September 2021). Are asthma symptom intensity scales better than biomarkers for diagnosing asthma? A prospective observational study [Poster presentation]. ERS International Congress 2021 (Virtual). |
![]() ![]() | Louis, G., Pétré, B., SCHLEICH, F., Nekoee Zahraei, H., Donneau, A.-F., Silvestre, A., HENKET, M., PAULUS, V., GUISSARD, F., Guillaume, M., & Louis, R. (2021). Predictors of asthma-related quality of life in a large cohort of asthmatics : A cross-sectional study in a secondary care center. Clinical and Translational Allergy. doi:10.1002/clt2.12054 ![]() |
![]() ![]() | Zanella, D., GUIOT, J., Stefanuto, P.-H., GILTAY, L., HENKET, M., GUISSARD, F., ANDRE, B., MALAISE, M., Pojtewijd, J., SCHLEICH, F., Louis, R., & Focant, J.-F. (2021). Breathomics to diagnose systemic sclerosis using thermal desorption and comprehensive two-dimensional gas chromatography high-resolution time-of-flight mass spectrometry. Analytical and Bioanalytical Chemistry. doi:10.1007/s00216-021-03333-4 ![]() |
![]() ![]() | Zanella, D., GUIOT, J., Stefanuto, P.-H., GILTAY, L., HENKET, M., GUISSARD, F., ANDRE, B., MALAISE, M., Potjewijd, J., SCHLEICH, F., LOUIS, R., & Focant, J.-F. (2021). TD-GC×GC-HRTOFMS for Breath Profiling of Systemic Sclerosis. In Proceedings. ![]() |
![]() ![]() | Schleich, F., Graff, S., GUISSARD, F., HENKET, M., Paulus, V., & Louis, R. (2021). Asthma in elderly is characterized by increased sputum neutrophils, lower airway caliber variability and air trapping. Respiratory Research, 22 (1), 15. doi:10.1186/s12931-021-01619-w ![]() |
![]() ![]() | Calmes, D., Huynen, P., Paulus, V., Henket, M., Guissard, F., Moermans, C., Louis, R., & Schleich, F. (2021). Chronic infection with Chlamydia pneumoniae in asthma: a type-2 low infection related phenotype. Respiratory Research, 22 (1), 72. doi:10.1186/s12931-021-01635-w ![]() |
![]() ![]() | Graff, S., Zanella, D., Stefanuto, P.-H., HENKET, M., PAULUS, V., GUISSARD, F., MOERMANS, C., Van Steen, K., Louis, R., & Schleich, F. (2021). Are Volatile Organic Compounds Able to Identify Airflow Decline in Asthma? Journal of Asthma and Allergy, 14, 67-70. doi:10.2147/JAA.S289278 ![]() |
![]() ![]() | Gerday, S., SCHLEICH, F., HENKET, M., GUISSARD, F., PAULUS, V., & LOUIS, R. (2021). Asthmatics with concordant eosinophilic disease classified according to their serum IgE status. Respiratory Medicine and Research. doi:10.1016/j.resmer.2020.100797 ![]() |
![]() ![]() | Graff, S., Bricmont, N., MOERMANS, C., HENKET, M., PAULUS, V., GUISSARD, F., LOUIS, R., & SCHLEICH, F. (2020). Clinical and biological factors associated with irreversible airway obstruction in adult asthma. Respiratory Medicine. doi:10.1016/j.rmed.2020.106202 ![]() |
![]() ![]() | Nekoee Zahraei, H., GUISSARD, F., Paulus, V., HENKET, M., Donneau, A.-F., & Louis, R. (2020). Comprehensive Cluster Analysis for COPD Including Systemic and Airway Inflammatory Markers. COPD: Journal of Chronic Obstructive Pulmonary Disease, 1-12. doi:10.1080/15412555.2020.1833853 |
![]() ![]() | Nekoee Zahraei, H., Graulich, E., SCHLEICH, F., GUISSARD, F., Paulus, V., HENKET, M., Donneau, A.-F., & Louis, R. (07 September 2020). Are T2 biomarkers of any help in asthma diagnosis? [Paper presentation]. ERS VIRTUAL CONGRESS 2020. |
![]() ![]() | Nekoee Zahraei, H., Graulich, E., Schleich, F., GUISSARD, F., Paulus, V., HENKET, M., Donneau, A.-F., & Louis, R. (06 July 2020). Are type-2 biomarkers of any help in asthma diagnosis? [letter to the editor]. ERJ Open Research, 6. doi:10.1183/23120541.00169-2020 ![]() |
![]() ![]() | Louis, R., Bougard, N., GUISSARD, F., PAULUS, V., HENKET, M., & Schleich, F. (February 2020). Bronchodilation Test with Inhaled Salbutamol Versus Bronchial Methacholine Challenge to Make an Asthma Diagnosis: Do They Provide the Same Information? Journal of Allergy and Clinical Immunology: In Practice, 8 (2), 618-625.e8. doi:10.1016/j.jaip.2019.09.007 ![]() |
![]() ![]() | Schleich, F., Frix, A.-N., Paulus, V., Guissard, F., Sanchez, C., Henket, M., & Louis, R. (2020). Une décennie d’avancées dans l’asthme : l’apport des biothérapies. Revue Médicale de Liège, 75 (5-6), 350-355. ![]() |
![]() ![]() | Louis, G., Pétré, B., SCHLEICH, F., HENKET, M., PAULUS, V., GUISSARD, F., LOUIS, R., & Guillaume, M. (2020). Relationship between quality of life and disordered physiology and cytology in asthma : a retrospective study from a secondary care center [Poster presentation]. Virtual ERS International Congress. |
![]() ![]() | Peerboom, S., Graff, S., SEIDEL, L., PAULUS, V., HENKET, M., SANCHEZ, C., GUISSARD, F., MOERMANS, C., LOUIS, R., & SCHLEICH, F. (2020). Predictors of a good response to inhaled corticosteroids in obesity-associated asthma. Biochemical Pharmacology. doi:10.1016/j.bcp.2020.113994 ![]() |
![]() ![]() | Schleich, F., Kehl, F., Ziant, S., Guissard, F., Hermans, P., & Louis, R. (2020). Le yoga en vue d’améliorer le contrôle symptomatique des patients asthmatiques sévères traités par biologiques. Revue Médicale de Liège, 75 (10), 682-685. ![]() |
![]() ![]() | SCHLEICH, F., Graff, S., Nekoee Zahraei, H., MOERMANS, C., HENKET, M., SANCHEZ, C., PAULUS, V., GUISSARD, F., Donneau, A.-F., & Louis, R. (2020). Real-word experience with mepolizumab: Does it deliver what it has promised? Clinical and Experimental Allergy. doi:10.1111/cea.13601 ![]() |
Gerday, S., SCHLEICH, F., HENKET, M., GUISSARD, F., PAULUS, V., & Louis, R. (2020). Comparison of demographic, functional and inflammatory features between atopic and non atopic asthmatics. Retrospective study on a large cohort of patients [Paper presentation]. ERS 2020 Virtual Congress. |
![]() ![]() | Bougard, N., Nekoee Zahraei, H., SCHLEICH, F., GUISSARD, F., PAULUS, V., Donneau, A.-F., & Louis, R. (2020). Assessment of diagnostic accuracy of lung function indices and FeNO for a positive methacholine challenge. Biochemical Pharmacology. doi:10.1016/j.bcp.2020.113981 ![]() |
![]() ![]() | Frix, A.-N., Schleich, F., PAULUS, V., GUISSARD, F., HENKET, M., & Louis, R. (2020). Effectiveness of omalizumab on patient reported outcomes, lung function, and inflammatory markers in severe allergic asthma. Biochemical Pharmacology, 179. doi:10.1016/j.bcp.2020.113944 ![]() |
![]() ![]() | Nekoee Zahraei, H., GUISSARD, F., PAULUS, V., HENKET, M., Donneau, A.-F., & Louis, R. (01 October 2019). Use of Principal Component and Cluster Analysis to Describe Phenotypes in COPD [Poster presentation]. ERS INTERNATIONAL CONGRESS 2019. |
Gerday, S., Schleich, F., Henket, M., GUISSARD, F., PAULUS, V., & Louis, R. (08 May 2019). Characterisation of a cohort of asthmatics with severe concordant eosinophilic disease according to their IgE status [Paper presentation]. GSK-SBP Pulmonology Award 2019. |
Gerday, S., SCHLEICH, F., HENKET, M., GUISSARD, F., PAULUS, V., & Louis, R. (2019). Characterisation of a cohort of asthmatics with severe concordant eosinophilic disease according to their IgE status [Paper presentation]. ERS International Congress. |