![]() ![]() | Zahraei, H. N., Schleich, F., Louis, G., Gerday, S., SABBE, M., Bougard, N., GUISSARD, F., PAULUS, V., Henket, M., Pétré, B., Donneau, A.-F., & Louis, R. (2024). Evidence for two clusters among non-eosinophilic asthmatics. Annals of Allergy, Asthma and Immunology. doi:10.1016/j.anai.2024.03.012 ![]() |
![]() ![]() | Schleich, F., Moermans, C., Seidel, L., Kempeneers, C., Louis, G., ROGISTER, F., Tombu, S., Pottier, L., Poirrier, A.-L., ZIANT, S., Henket, M., SANCHEZ, C., PAULUS, V., GUISSARD, F., Donneau, A.-F., & Louis, R. (November 2023). Benralizumab in severe eosinophilic asthma in real life: confirmed effectiveness and contrasted effect on sputum eosinophilia versus exhaled nitric oxide fraction - PROMISE. ERJ Open Research, 9 (6). doi:10.1183/23120541.00383-2023 ![]() |
![]() ![]() | Schleich, F., Moermans, C., Gerday, S., ZIANT, S., Louis, G., Bougard, N., PAULUS, V., GUISSARD, F., Henket, M., Bachert, C., & Louis, R. (October 2023). Patients With Asthma Only Sensitized to Staphylococcus aureus Enterotoxins Have More Exacerbations, Airflow Limitation, and Higher Levels of Sputum IL-5 and IgE. Journal of Allergy and Clinical Immunology: In Practice, 11 (10), 3055-3061.e4. doi:10.1016/j.jaip.2023.05.043 ![]() |
![]() ![]() | Gerday, S., Graff, S., Moermans, C., GUISSARD, F., PAULUS, V., Henket, M., Louis, R., & Schleich, F. (2023). Super-responders to anti-IL-5/anti-IL-5R are characterised by high sputum eosinophil counts at baseline. Thorax, 2022-219781. doi:10.1136/thorax-2022-219781 ![]() |
![]() ![]() | Zahraei, H. N., Schleich, F., Gerday, S., GUISSARD, F., PAULUS, V., Henket, M., Moermans, C., Donneau, A.-F.* , & Louis, R.*. (June 2023). A clustering analysis of eosinophilic asthmatics: Two clusters with sharp differences in atopic status and disease severity. Clinical and Experimental Allergy, 53 (6), 672-678. doi:10.1111/cea.14312 ![]() * These authors have contributed equally to this work. |
![]() ![]() | Moermans, C., Brion, C., BOCK, G., Graff, S., Gerday, S., Nekoee, H., Poulet, C., Bricmont, N., Henket, M., PAULUS, V., GUISSARD, F., Louis, R., & Schleich, F. (2023). Sputum Type 2 Markers Could Predict Remission in Severe Asthma Treated With Anti-IL-5. CHEST. doi:10.1016/j.chest.2023.01.037 ![]() |
![]() ![]() | Louis, G., Pétré, B., Schleich, F., Zahrei, H. N., Donneau, A.-F., Henket, M., PAULUS, V., GUISSARD, F., Guillaume, M., & Louis, R. (2023). Predictors of change in asthma-related quality of life: a longitudinal real-life study in adult asthmatics. Quality of Life Research. doi:10.1007/s11136-022-03339-0 ![]() |
![]() ![]() | Louis, G., Schleich, F., Guillaume, M., Kirkove, D., Zahrei, H., Donneau, A.-F., Henket, M., PAULUS, V., GUISSARD, F., Louis, R., & Pétré, B. (2023). Development and validation of a predictive model combining patient-reported outcome measures, spirometry and exhaled nitric oxide fraction for asthma diagnosis. ERJ Open Research, 00451-2022. doi:10.1183/23120541.00451-2022 ![]() |
![]() ![]() | Gerday, S., SCHLEICH, F., Henket, M., GUISSARD, F., PAULUS, V., & LOUIS, R. (01 June 2022). Revisiting differences between atopic and non-atopic asthmatics: When age is shaping airway inflammatory profile. World Allergy Organization Journal, 15 (6), 100655. doi:10.1016/j.waojou.2022.100655 ![]() |
Gerday, S., Henket, M., GUISSARD, F., PAULUS, V., Louis, R., & Schleich, F. (17 May 2022). Super responders to mepolizumab are characterized by high sputum eosinophils and FeNO at baseline [Poster presentation]. ATS International Conference, San Francisco, United States. |
![]() ![]() | Louis, G., Pétré, B., SCHLEICH, F., Nekoee Zahraei, H., Donneau, A.-F., HENKET, M., PAULUS, V., GUISSARD, F., Guillaume, M., & LOUIS, R. (2022). A Real Life Longitudinal Study on Asthma-Related Quality of Life in a Secondary Care Center. American Journal of Respiratory and Critical Care Medicine. doi:10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1334 ![]() |
Nekoee Zahraei, H., SCHLEICH, F., HENKET, M., PAULUS, V., Gerday, S., GUISSARD, F., Donneau, A.-F., & LOUIS, R. (15 May 2022). A clustering analysis of eosinophilic asthmatics [Paper presentation]. The American Thoracic Society International Conference ATS, San Francisco, United States - California. ![]() |
![]() ![]() | Schleich, F., Graff, S., Bougard, N., Frix, A.-N., Peerboom, S., Demarche, S., GUISSARD, F., PAULUS, V., Henket, M., CALMES, D., Moermans, C., & Louis, R. (May 2022). L’asthme bronchique en pratique clinique : des phénotypes inflammatoires au traitement personnalisé. Revue Médicale de Liège, 77 (5-6), 289-294. ![]() |
![]() ![]() | Louis, G., SCHLEICH, F., Guillaume, M., Donneau, A.-F., Nekoee Zahraei, H., HENKET, M., PAULUS, V., GUISSARD, F., Louis, R., & Pétré, B. (05 September 2021). Are asthma symptom intensity scales better than biomarkers for diagnosing asthma? A prospective observational study [Poster presentation]. ERS International Congress 2021 (Virtual). |
![]() ![]() | Louis, G., Pétré, B., SCHLEICH, F., Nekoee Zahraei, H., Donneau, A.-F., Silvestre, A., HENKET, M., PAULUS, V., GUISSARD, F., Guillaume, M., & Louis, R. (2021). Predictors of asthma-related quality of life in a large cohort of asthmatics : A cross-sectional study in a secondary care center. Clinical and Translational Allergy. doi:10.1002/clt2.12054 ![]() |
![]() ![]() | Schleich, F., Graff, S., GUISSARD, F., HENKET, M., Paulus, V., & Louis, R. (2021). Asthma in elderly is characterized by increased sputum neutrophils, lower airway caliber variability and air trapping. Respiratory Research, 22 (1), 15. doi:10.1186/s12931-021-01619-w ![]() |
![]() ![]() | Calmes, D., Huynen, P., Paulus, V., Henket, M., Guissard, F., Moermans, C., Louis, R., & Schleich, F. (2021). Chronic infection with Chlamydia pneumoniae in asthma: a type-2 low infection related phenotype. Respiratory Research, 22 (1), 72. doi:10.1186/s12931-021-01635-w ![]() |
![]() ![]() | Gerday, S., SCHLEICH, F., HENKET, M., GUISSARD, F., PAULUS, V., & LOUIS, R. (2021). Asthmatics with concordant eosinophilic disease classified according to their serum IgE status. Respiratory Medicine and Research. doi:10.1016/j.resmer.2020.100797 ![]() |
![]() ![]() | Graff, S., Zanella, D., Stefanuto, P.-H., HENKET, M., PAULUS, V., GUISSARD, F., MOERMANS, C., Van Steen, K., Louis, R., & Schleich, F. (2021). Are Volatile Organic Compounds Able to Identify Airflow Decline in Asthma? Journal of Asthma and Allergy, 14, 67-70. doi:10.2147/JAA.S289278 ![]() |
![]() ![]() | CALMES, D., Graff, S., MAES, N., Frix, A.-N., THYS, M., BONHOMME, O., Berg, J., DEBRUCHE, M., GESTER, F., HENKET, M., PAULUS, V., DUYSINX, B., HEINEN, V., NGUYEN DANG, D., PAULUS, A., QUAEDVLIEG, V., VAILLANT, F., VAN CAUWENBERGE, H., MALAISE, M., ... SCHLEICH, F. (2021). Asthma and COPD Are Not Risk Factors for ICU Stay and Death in Case of SARS-CoV2 Infection. Journal of Allergy and Clinical Immunology: In Practice, 9 (1), 160-169. doi:10.1016/j.jaip.2020.09.044 ![]() |
![]() ![]() | Graff, S., Bricmont, N., MOERMANS, C., HENKET, M., PAULUS, V., GUISSARD, F., LOUIS, R., & SCHLEICH, F. (2020). Clinical and biological factors associated with irreversible airway obstruction in adult asthma. Respiratory Medicine. doi:10.1016/j.rmed.2020.106202 ![]() |
![]() ![]() | Nekoee Zahraei, H., Graulich, E., SCHLEICH, F., GUISSARD, F., Paulus, V., HENKET, M., Donneau, A.-F., & Louis, R. (07 September 2020). Are T2 biomarkers of any help in asthma diagnosis? [Paper presentation]. ERS VIRTUAL CONGRESS 2020. |
![]() ![]() | Louis, R., Bougard, N., GUISSARD, F., PAULUS, V., HENKET, M., & Schleich, F. (February 2020). Bronchodilation Test with Inhaled Salbutamol Versus Bronchial Methacholine Challenge to Make an Asthma Diagnosis: Do They Provide the Same Information? Journal of Allergy and Clinical Immunology: In Practice, 8 (2), 618-625.e8. doi:10.1016/j.jaip.2019.09.007 ![]() |
![]() ![]() | Bougard, N., Nekoee Zahraei, H., SCHLEICH, F., GUISSARD, F., PAULUS, V., Donneau, A.-F., & Louis, R. (2020). Assessment of diagnostic accuracy of lung function indices and FeNO for a positive methacholine challenge. Biochemical Pharmacology. doi:10.1016/j.bcp.2020.113981 ![]() |
![]() ![]() | Frix, A.-N., Schleich, F., PAULUS, V., GUISSARD, F., HENKET, M., & Louis, R. (2020). Effectiveness of omalizumab on patient reported outcomes, lung function, and inflammatory markers in severe allergic asthma. Biochemical Pharmacology, 179. doi:10.1016/j.bcp.2020.113944 ![]() |
Gerday, S., SCHLEICH, F., HENKET, M., GUISSARD, F., PAULUS, V., & Louis, R. (2020). Comparison of demographic, functional and inflammatory features between atopic and non atopic asthmatics. Retrospective study on a large cohort of patients [Paper presentation]. ERS 2020 Virtual Congress. |
![]() ![]() | Louis, G., Pétré, B., SCHLEICH, F., HENKET, M., PAULUS, V., GUISSARD, F., LOUIS, R., & Guillaume, M. (2020). Relationship between quality of life and disordered physiology and cytology in asthma : a retrospective study from a secondary care center [Poster presentation]. Virtual ERS International Congress. |
![]() ![]() | SCHLEICH, F., Graff, S., Nekoee Zahraei, H., MOERMANS, C., HENKET, M., SANCHEZ, C., PAULUS, V., GUISSARD, F., Donneau, A.-F., & Louis, R. (2020). Real-word experience with mepolizumab: Does it deliver what it has promised? Clinical and Experimental Allergy. doi:10.1111/cea.13601 ![]() |
![]() ![]() | Peerboom, S., Graff, S., SEIDEL, L., PAULUS, V., HENKET, M., SANCHEZ, C., GUISSARD, F., MOERMANS, C., LOUIS, R., & SCHLEICH, F. (2020). Predictors of a good response to inhaled corticosteroids in obesity-associated asthma. Biochemical Pharmacology. doi:10.1016/j.bcp.2020.113994 ![]() |
![]() ![]() | Schleich, F., Frix, A.-N., Paulus, V., Guissard, F., Sanchez, C., Henket, M., & Louis, R. (2020). Une décennie d’avancées dans l’asthme : l’apport des biothérapies. Revue Médicale de Liège, 75 (5-6), 350-355. ![]() |
![]() ![]() | Nekoee Zahraei, H., GUISSARD, F., PAULUS, V., HENKET, M., Donneau, A.-F., & Louis, R. (01 October 2019). Use of Principal Component and Cluster Analysis to Describe Phenotypes in COPD [Poster presentation]. ERS INTERNATIONAL CONGRESS 2019. |
![]() ![]() | Graff, S., Demarche, S., HENKET, M., PAULUS, V., Louis, R., & SCHLEICH, F. (June 2019). Increase in blood eosinophils during follow-up is associated with lung function decline in adult asthma. Respiratory Medicine, 152, 60-66. doi:10.1016/j.rmed.2019.04.020 ![]() |
Gerday, S., Schleich, F., Henket, M., GUISSARD, F., PAULUS, V., & Louis, R. (08 May 2019). Characterisation of a cohort of asthmatics with severe concordant eosinophilic disease according to their IgE status [Paper presentation]. GSK-SBP Pulmonology Award 2019. |
Gerday, S., SCHLEICH, F., HENKET, M., GUISSARD, F., PAULUS, V., & Louis, R. (2019). Characterisation of a cohort of asthmatics with severe concordant eosinophilic disease according to their IgE status [Paper presentation]. ERS International Congress. |
![]() ![]() | Frix, A.-N., HEINEN, V., SCHLEICH, F., DUYSINX, B., PAULUS, V., & Louis, R. (2019). Thermoplastie bronchique dans le traitement de l’asthme sévère. Analyse rétrospective de 10 cas traités au CHU de Liège. Revue Médicale de Liège, 74 (2), 74-81. ![]() |
![]() ![]() | Nekoee Zahraei, H., PAULUS, V., HENKET, M., Louis, R., & Donneau, A.-F. (17 July 2018). Identification of Chronic Obstructive Pulmonary Disease Phenotype using PCA and Clustering Methodologies [Poster presentation]. 40th International Society for Clinical Biostatistics (ISCB40), Leuven, Belgium. |
![]() ![]() | Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., Louis, R., & Van Hees, T. (09 January 2018). Step-down of inhaled corticosteroids in non-eosinophilic asthma: A prospective trial in real life. Clinical and Experimental Allergy, 48 (5), 525-535. doi:10.1111/cea.13106 ![]() |
![]() ![]() | GUIOT, J., Demarche, S., HENKET, M., PAULUS, V., Graff, S., SCHLEICH, F., Corhay, J.-L., Louis, R., & MOERMANS, C. (2017). Methodology for Sputum Induction and Laboratory Processing. Journal of Visualized Experiments, (130). doi:10.3791/56612 ![]() |
![]() ![]() | Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., Van Hees, T., & Louis, R. (May 2017). How to Approach Eosinophilic Versus Non-eosinophilic Asthma in Clinical Practice Using Biomarkers? [Poster presentation]. American Thoracic Society International Conference 2017, Washington DC, United States. |
![]() ![]() | Demarche, S., Schleich, F., HENKET, M., PAULUS, V., Van Hees, T., & Louis, R. (2017). Effectiveness of inhaled corticosteroids in real life on clinical outcomes, sputum cells and systemic inflammation in asthmatics: a retrospective cohort study in a secondary care centre. BMJ Open, 7 (11), 018186. doi:10.1136/bmjopen-2017-018186 ![]() |
![]() ![]() | Demarche, S., Schleich, F., PAULUS, V., HENKET, M., Van Hees, T., & Louis, R. (2017). Is it possible to claim or refute sputum eosinophils ≥ 3% in asthmatics with sufficient accuracy using biomarkers? [letter to the editor]. Respiratory Research, 18 (1), 133-139. doi:10.1186/s12931-017-0615-9 ![]() |
![]() ![]() | Demarche, S., SCHLEICH, F., PAULUS, V., HENKET, M., Van Hees, T., & Louis, R. (2017). Asthma Control and Sputum Eosinophils: A Longitudinal Study in Daily Practice. Journal of Allergy and Clinical Immunology: In Practice, 5 (5), 1335-1343.e5. doi:10.1016/j.jaip.2017.01.026 ![]() |
![]() ![]() | Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., VAN HEES, T., & LOUIS, R. (05 April 2016). Detailed analysis of sputum and systemic inflammation in asthma phenotypes: are paucigranulocytic asthmatics really non-inflammatory? BMC Pulmonary Medicine, 16, 46. doi:10.1186/s12890-016-0208-2 ![]() |
![]() ![]() | Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., Van Hees, T., & Louis, R. (27 September 2015). Asthma Control and Sputum Eosinophils: a Longitudinal Study in Daily Practice [Poster presentation]. ERS Amsterdam 2015 International Congress, Amsterdam, Netherlands. |
Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., Van Hees, T., & Louis, R. (12 June 2015). Asthma Control and Sputum Eosinophils: a Longitudinal Study in Daily Practice [Paper presentation]. AIRe WAY II, 3th annual scientific meeting. |
Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., VAN HEES, T., & LOUIS, R. (02 June 2015). Asthma Control and Sputum Eosinophils: a Longitudinal Study in Daily Practice [Poster presentation]. Biomedica Summit 2015. |
![]() ![]() | WARNIER, H., Schleich, F., PAULUS, V., & Louis, R. (2015). Analyse des facteurs associés à la réversibilité au salbutamol dans une cohorte de patients asthmatiques en pratique clinique. Revue des Maladies Respiratoires. ![]() |
![]() ![]() | SCHLEICH, F., Chevremont, A., PAULUS, V., HENKET, M., Manise, M., Seidel, L., & Louis, R. (2014). Importance of concomitant local and systemic eosinophilia in uncontrolled asthma. European Respiratory Journal, 44, 97-108. doi:10.1183/09031936.00201813 ![]() |
Delsaute, M., Berlemont, R., Paulus, V., Bauvois, C., Wei, Q., Cornelis, P., & Galleni, M. (2011). Cellulase involvement in the cellulose biosynthesis of Pseudomonas stutzeri [Poster presentation]. 13th International Conference on Pseudomonas, Sydney, Australia. |