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PAULUS Virginie

Département de médecine interne > Clinique de l'asthme

See author's contact details
Main Referenced Co-authors
Louis, Renaud  (47)
Schleich, Florence  (46)
Henket, Monique  (45)
Guissard, Françoise  (32)
Donneau, Anne-Françoise  (14)
Main Referenced Keywords
Asthma (13); Eosinophils (7); Humans (7); Sputum (6); Asthma control (5);
Main Referenced Unit & Research Centers
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (1)
Centre Interfacultaire de Recherche du Médicament - CIRM (1)
GIGA-I3 - Giga-Infection, Immunity and Inflammation - ULiège [BE] (1)
Main Referenced Disciplines
Cardiovascular & respiratory systems (35)
Public health, health care sciences & services (9)
Pharmacy, pharmacology & toxicology (3)
General & internal medicine (2)
Biochemistry, biophysics & molecular biology (1)

Publications (total 49)

The most downloaded
235 downloads
Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., Louis, R., & Van Hees, T. (09 January 2018). Step-down of inhaled corticosteroids in non-eosinophilic asthma: A prospective trial in real life. Clinical and Experimental Allergy, 48 (5), 525-535. doi:10.1111/cea.13106 https://hdl.handle.net/2268/226775

The most cited

152 citations (Scopus®)

SCHLEICH, F., Chevremont, A., PAULUS, V., HENKET, M., Manise, M., Seidel, L., & Louis, R. (2014). Importance of concomitant local and systemic eosinophilia in uncontrolled asthma. European Respiratory Journal, 44, 97-108. doi:10.1183/09031936.00201813 https://hdl.handle.net/2268/167600

Zahraei, H. N., Schleich, F., Louis, G., Gerday, S., SABBE, M., Bougard, N., GUISSARD, F., PAULUS, V., Henket, M., Pétré, B., Donneau, A.-F., & Louis, R. (2024). Evidence for two clusters among non-eosinophilic asthmatics. Annals of Allergy, Asthma and Immunology. doi:10.1016/j.anai.2024.03.012
Peer Reviewed verified by ORBi

Schleich, F., Moermans, C., Seidel, L., Kempeneers, C., Louis, G., ROGISTER, F., Tombu, S., Pottier, L., Poirrier, A.-L., ZIANT, S., Henket, M., SANCHEZ, C., PAULUS, V., GUISSARD, F., Donneau, A.-F., & Louis, R. (November 2023). Benralizumab in severe eosinophilic asthma in real life: confirmed effectiveness and contrasted effect on sputum eosinophilia versus exhaled nitric oxide fraction - PROMISE. ERJ Open Research, 9 (6). doi:10.1183/23120541.00383-2023
Peer Reviewed verified by ORBi

Schleich, F., Moermans, C., Gerday, S., ZIANT, S., Louis, G., Bougard, N., PAULUS, V., GUISSARD, F., Henket, M., Bachert, C., & Louis, R. (October 2023). Patients With Asthma Only Sensitized to Staphylococcus aureus Enterotoxins Have More Exacerbations, Airflow Limitation, and Higher Levels of Sputum IL-5 and IgE. Journal of Allergy and Clinical Immunology: In Practice, 11 (10), 3055-3061.e4. doi:10.1016/j.jaip.2023.05.043
Peer Reviewed verified by ORBi

Gerday, S., Graff, S., Moermans, C., GUISSARD, F., PAULUS, V., Henket, M., Louis, R., & Schleich, F. (2023). Super-responders to anti-IL-5/anti-IL-5R are characterised by high sputum eosinophil counts at baseline. Thorax, 2022-219781. doi:10.1136/thorax-2022-219781
Peer Reviewed verified by ORBi

Zahraei, H. N., Schleich, F., Gerday, S., GUISSARD, F., PAULUS, V., Henket, M., Moermans, C., Donneau, A.-F.* , & Louis, R.*. (June 2023). A clustering analysis of eosinophilic asthmatics: Two clusters with sharp differences in atopic status and disease severity. Clinical and Experimental Allergy, 53 (6), 672-678. doi:10.1111/cea.14312
Peer reviewed
* These authors have contributed equally to this work.

Moermans, C., Brion, C., BOCK, G., Graff, S., Gerday, S., Nekoee, H., Poulet, C., Bricmont, N., Henket, M., PAULUS, V., GUISSARD, F., Louis, R., & Schleich, F. (2023). Sputum Type 2 Markers Could Predict Remission in Severe Asthma Treated With Anti-IL-5. CHEST. doi:10.1016/j.chest.2023.01.037
Peer Reviewed verified by ORBi

Louis, G., Pétré, B., Schleich, F., Zahrei, H. N., Donneau, A.-F., Henket, M., PAULUS, V., GUISSARD, F., Guillaume, M., & Louis, R. (2023). Predictors of change in asthma-related quality of life: a longitudinal real-life study in adult asthmatics. Quality of Life Research. doi:10.1007/s11136-022-03339-0
Peer Reviewed verified by ORBi

Louis, G., Schleich, F., Guillaume, M., Kirkove, D., Zahrei, H., Donneau, A.-F., Henket, M., PAULUS, V., GUISSARD, F., Louis, R., & Pétré, B. (2023). Development and validation of a predictive model combining patient-reported outcome measures, spirometry and exhaled nitric oxide fraction for asthma diagnosis. ERJ Open Research, 00451-2022. doi:10.1183/23120541.00451-2022
Peer Reviewed verified by ORBi

Gerday, S., SCHLEICH, F., Henket, M., GUISSARD, F., PAULUS, V., & LOUIS, R. (01 June 2022). Revisiting differences between atopic and non-atopic asthmatics: When age is shaping airway inflammatory profile. World Allergy Organization Journal, 15 (6), 100655. doi:10.1016/j.waojou.2022.100655
Peer Reviewed verified by ORBi

Gerday, S., Henket, M., GUISSARD, F., PAULUS, V., Louis, R., & Schleich, F. (17 May 2022). Super responders to mepolizumab are characterized by high sputum eosinophils and FeNO at baseline [Poster presentation]. ATS International Conference, San Francisco, United States.

Louis, G., Pétré, B., SCHLEICH, F., Nekoee Zahraei, H., Donneau, A.-F., HENKET, M., PAULUS, V., GUISSARD, F., Guillaume, M., & LOUIS, R. (2022). A Real Life Longitudinal Study on Asthma-Related Quality of Life in a Secondary Care Center. American Journal of Respiratory and Critical Care Medicine. doi:10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1334
Peer Reviewed verified by ORBi

Nekoee Zahraei, H., SCHLEICH, F., HENKET, M., PAULUS, V., Gerday, S., GUISSARD, F., Donneau, A.-F., & LOUIS, R. (15 May 2022). A clustering analysis of eosinophilic asthmatics [Paper presentation]. The American Thoracic Society International Conference ATS, San Francisco, United States - California.
Editorial reviewed

Schleich, F., Graff, S., Bougard, N., Frix, A.-N., Peerboom, S., Demarche, S., GUISSARD, F., PAULUS, V., Henket, M., CALMES, D., Moermans, C., & Louis, R. (May 2022). L’asthme bronchique en pratique clinique : des phénotypes inflammatoires au traitement personnalisé. Revue Médicale de Liège, 77 (5-6), 289-294.
Editorial Reviewed verified by ORBi

Louis, G., SCHLEICH, F., Guillaume, M., Donneau, A.-F., Nekoee Zahraei, H., HENKET, M., PAULUS, V., GUISSARD, F., Louis, R., & Pétré, B. (05 September 2021). Are asthma symptom intensity scales better than biomarkers for diagnosing asthma? A prospective observational study [Poster presentation]. ERS International Congress 2021 (Virtual).

Louis, G., Pétré, B., SCHLEICH, F., Nekoee Zahraei, H., Donneau, A.-F., Silvestre, A., HENKET, M., PAULUS, V., GUISSARD, F., Guillaume, M., & Louis, R. (2021). Predictors of asthma-related quality of life in a large cohort of asthmatics : A cross-sectional study in a secondary care center. Clinical and Translational Allergy. doi:10.1002/clt2.12054
Peer Reviewed verified by ORBi

Schleich, F., Graff, S., GUISSARD, F., HENKET, M., Paulus, V., & Louis, R. (2021). Asthma in elderly is characterized by increased sputum neutrophils, lower airway caliber variability and air trapping. Respiratory Research, 22 (1), 15. doi:10.1186/s12931-021-01619-w
Peer Reviewed verified by ORBi

Calmes, D., Huynen, P., Paulus, V., Henket, M., Guissard, F., Moermans, C., Louis, R., & Schleich, F. (2021). Chronic infection with Chlamydia pneumoniae in asthma: a type-2 low infection related phenotype. Respiratory Research, 22 (1), 72. doi:10.1186/s12931-021-01635-w
Peer Reviewed verified by ORBi

Gerday, S., SCHLEICH, F., HENKET, M., GUISSARD, F., PAULUS, V., & LOUIS, R. (2021). Asthmatics with concordant eosinophilic disease classified according to their serum IgE status. Respiratory Medicine and Research. doi:10.1016/j.resmer.2020.100797
Peer Reviewed verified by ORBi

Graff, S., Zanella, D., Stefanuto, P.-H., HENKET, M., PAULUS, V., GUISSARD, F., MOERMANS, C., Van Steen, K., Louis, R., & Schleich, F. (2021). Are Volatile Organic Compounds Able to Identify Airflow Decline in Asthma? Journal of Asthma and Allergy, 14, 67-70. doi:10.2147/JAA.S289278
Peer Reviewed verified by ORBi

CALMES, D., Graff, S., MAES, N., Frix, A.-N., THYS, M., BONHOMME, O., Berg, J., DEBRUCHE, M., GESTER, F., HENKET, M., PAULUS, V., DUYSINX, B., HEINEN, V., NGUYEN DANG, D., PAULUS, A., QUAEDVLIEG, V., VAILLANT, F., VAN CAUWENBERGE, H., MALAISE, M., ... SCHLEICH, F. (2021). Asthma and COPD Are Not Risk Factors for ICU Stay and Death in Case of SARS-CoV2 Infection. Journal of Allergy and Clinical Immunology: In Practice, 9 (1), 160-169. doi:10.1016/j.jaip.2020.09.044
Peer Reviewed verified by ORBi

Graff, S., Bricmont, N., MOERMANS, C., HENKET, M., PAULUS, V., GUISSARD, F., LOUIS, R., & SCHLEICH, F. (2020). Clinical and biological factors associated with irreversible airway obstruction in adult asthma. Respiratory Medicine. doi:10.1016/j.rmed.2020.106202
Peer Reviewed verified by ORBi

Nekoee Zahraei, H., Graulich, E., SCHLEICH, F., GUISSARD, F., Paulus, V., HENKET, M., Donneau, A.-F., & Louis, R. (07 September 2020). Are T2 biomarkers of any help in asthma diagnosis? [Paper presentation]. ERS VIRTUAL CONGRESS 2020.

Louis, R., Bougard, N., GUISSARD, F., PAULUS, V., HENKET, M., & Schleich, F. (February 2020). Bronchodilation Test with Inhaled Salbutamol Versus Bronchial Methacholine Challenge to Make an Asthma Diagnosis: Do They Provide the Same Information? Journal of Allergy and Clinical Immunology: In Practice, 8 (2), 618-625.e8. doi:10.1016/j.jaip.2019.09.007
Peer Reviewed verified by ORBi

Bougard, N., Nekoee Zahraei, H., SCHLEICH, F., GUISSARD, F., PAULUS, V., Donneau, A.-F., & Louis, R. (2020). Assessment of diagnostic accuracy of lung function indices and FeNO for a positive methacholine challenge. Biochemical Pharmacology. doi:10.1016/j.bcp.2020.113981
Peer Reviewed verified by ORBi

Frix, A.-N., Schleich, F., PAULUS, V., GUISSARD, F., HENKET, M., & Louis, R. (2020). Effectiveness of omalizumab on patient reported outcomes, lung function, and inflammatory markers in severe allergic asthma. Biochemical Pharmacology, 179. doi:10.1016/j.bcp.2020.113944
Peer Reviewed verified by ORBi

Gerday, S., SCHLEICH, F., HENKET, M., GUISSARD, F., PAULUS, V., & Louis, R. (2020). Comparison of demographic, functional and inflammatory features between atopic and non atopic asthmatics. Retrospective study on a large cohort of patients [Paper presentation]. ERS 2020 Virtual Congress.

SCHLEICH, F., Graff, S., Nekoee Zahraei, H., MOERMANS, C., HENKET, M., SANCHEZ, C., PAULUS, V., GUISSARD, F., Donneau, A.-F., & Louis, R. (2020). Real-word experience with mepolizumab: Does it deliver what it has promised? Clinical and Experimental Allergy. doi:10.1111/cea.13601
Peer Reviewed verified by ORBi

Louis, G., Pétré, B., SCHLEICH, F., HENKET, M., PAULUS, V., GUISSARD, F., LOUIS, R., & Guillaume, M. (2020). Relationship between quality of life and disordered physiology and cytology in asthma : a retrospective study from a secondary care center [Poster presentation]. Virtual ERS International Congress.

Peerboom, S., Graff, S., SEIDEL, L., PAULUS, V., HENKET, M., SANCHEZ, C., GUISSARD, F., MOERMANS, C., LOUIS, R., & SCHLEICH, F. (2020). Predictors of a good response to inhaled corticosteroids in obesity-associated asthma. Biochemical Pharmacology. doi:10.1016/j.bcp.2020.113994
Peer Reviewed verified by ORBi

Schleich, F., Frix, A.-N., Paulus, V., Guissard, F., Sanchez, C., Henket, M., & Louis, R. (2020). Une décennie d’avancées dans l’asthme : l’apport des biothérapies. Revue Médicale de Liège, 75 (5-6), 350-355.
Peer reviewed

Nekoee Zahraei, H., GUISSARD, F., PAULUS, V., HENKET, M., Donneau, A.-F., & Louis, R. (01 October 2019). Use of Principal Component and Cluster Analysis to Describe Phenotypes in COPD [Poster presentation]. ERS INTERNATIONAL CONGRESS 2019.

Graff, S., Demarche, S., HENKET, M., PAULUS, V., Louis, R., & SCHLEICH, F. (June 2019). Increase in blood eosinophils during follow-up is associated with lung function decline in adult asthma. Respiratory Medicine, 152, 60-66. doi:10.1016/j.rmed.2019.04.020
Peer Reviewed verified by ORBi

Gerday, S., Schleich, F., Henket, M., GUISSARD, F., PAULUS, V., & Louis, R. (08 May 2019). Characterisation of a cohort of asthmatics with severe concordant eosinophilic disease according to their IgE status [Paper presentation]. GSK-SBP Pulmonology Award 2019.

Gerday, S., SCHLEICH, F., HENKET, M., GUISSARD, F., PAULUS, V., & Louis, R. (2019). Characterisation of a cohort of asthmatics with severe concordant eosinophilic disease according to their IgE status [Paper presentation]. ERS International Congress.

Frix, A.-N., HEINEN, V., SCHLEICH, F., DUYSINX, B., PAULUS, V., & Louis, R. (2019). Thermoplastie bronchique dans le traitement de l’asthme sévère. Analyse rétrospective de 10 cas traités au CHU de Liège. Revue Médicale de Liège, 74 (2), 74-81.
Peer reviewed

Nekoee Zahraei, H., PAULUS, V., HENKET, M., Louis, R., & Donneau, A.-F. (17 July 2018). Identification of Chronic Obstructive Pulmonary Disease Phenotype using PCA and Clustering Methodologies [Poster presentation]. 40th International Society for Clinical Biostatistics (ISCB40), Leuven, Belgium.

Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., Louis, R., & Van Hees, T. (09 January 2018). Step-down of inhaled corticosteroids in non-eosinophilic asthma: A prospective trial in real life. Clinical and Experimental Allergy, 48 (5), 525-535. doi:10.1111/cea.13106
Peer Reviewed verified by ORBi

GUIOT, J., Demarche, S., HENKET, M., PAULUS, V., Graff, S., SCHLEICH, F., Corhay, J.-L., Louis, R., & MOERMANS, C. (2017). Methodology for Sputum Induction and Laboratory Processing. Journal of Visualized Experiments, (130). doi:10.3791/56612
Peer Reviewed verified by ORBi

Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., Van Hees, T., & Louis, R. (May 2017). How to Approach Eosinophilic Versus Non-eosinophilic Asthma in Clinical Practice Using Biomarkers? [Poster presentation]. American Thoracic Society International Conference 2017, Washington DC, United States.

Demarche, S., Schleich, F., PAULUS, V., HENKET, M., Van Hees, T., & Louis, R. (2017). Is it possible to claim or refute sputum eosinophils ≥ 3% in asthmatics with sufficient accuracy using biomarkers? [letter to the editor]. Respiratory Research, 18 (1), 133-139. doi:10.1186/s12931-017-0615-9
Peer Reviewed verified by ORBi

Demarche, S., SCHLEICH, F., PAULUS, V., HENKET, M., Van Hees, T., & Louis, R. (2017). Asthma Control and Sputum Eosinophils: A Longitudinal Study in Daily Practice. Journal of Allergy and Clinical Immunology: In Practice, 5 (5), 1335-1343.e5. doi:10.1016/j.jaip.2017.01.026
Peer Reviewed verified by ORBi

Demarche, S., Schleich, F., HENKET, M., PAULUS, V., Van Hees, T., & Louis, R. (2017). Effectiveness of inhaled corticosteroids in real life on clinical outcomes, sputum cells and systemic inflammation in asthmatics: a retrospective cohort study in a secondary care centre. BMJ Open, 7 (11), 018186. doi:10.1136/bmjopen-2017-018186
Peer Reviewed verified by ORBi

Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., VAN HEES, T., & LOUIS, R. (05 April 2016). Detailed analysis of sputum and systemic inflammation in asthma phenotypes: are paucigranulocytic asthmatics really non-inflammatory? BMC Pulmonary Medicine, 16, 46. doi:10.1186/s12890-016-0208-2
Peer Reviewed verified by ORBi

Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., Van Hees, T., & Louis, R. (27 September 2015). Asthma Control and Sputum Eosinophils: a Longitudinal Study in Daily Practice [Poster presentation]. ERS Amsterdam 2015 International Congress, Amsterdam, Netherlands.

Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., Van Hees, T., & Louis, R. (12 June 2015). Asthma Control and Sputum Eosinophils: a Longitudinal Study in Daily Practice [Paper presentation]. AIRe WAY II, 3th annual scientific meeting.

Demarche, S., SCHLEICH, F., HENKET, M., PAULUS, V., VAN HEES, T., & LOUIS, R. (02 June 2015). Asthma Control and Sputum Eosinophils: a Longitudinal Study in Daily Practice [Poster presentation]. Biomedica Summit 2015.

WARNIER, H., Schleich, F., PAULUS, V., & Louis, R. (2015). Analyse des facteurs associés à la réversibilité au salbutamol dans une cohorte de patients asthmatiques en pratique clinique. Revue des Maladies Respiratoires.
Peer Reviewed verified by ORBi

SCHLEICH, F., Chevremont, A., PAULUS, V., HENKET, M., Manise, M., Seidel, L., & Louis, R. (2014). Importance of concomitant local and systemic eosinophilia in uncontrolled asthma. European Respiratory Journal, 44, 97-108. doi:10.1183/09031936.00201813
Peer Reviewed verified by ORBi

Delsaute, M., Berlemont, R., Paulus, V., Bauvois, C., Wei, Q., Cornelis, P., & Galleni, M. (2011). Cellulase involvement in the cellulose biosynthesis of Pseudomonas stutzeri [Poster presentation]. 13th International Conference on Pseudomonas, Sydney, Australia.

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