Bekisz Sophie

GIGA Mol. & Comput. Biology - Biomechanics Research Unit

Département d'aérospatiale et mécanique > Génie biomécanique

See author's contact details
ORCID
0000-0001-5892-8723
Main Referenced Co-authors
Noël, Agnès  (29)
Geris, Liesbet  (26)
Comeliau, Loïc  (11)
Gautier, Marine  (11)
Bentley, Katie (8)
Main Referenced Keywords
In silico methods (3); Lymphangiogenesis (3); Blood (2); Computational models (2); Glucose (2);
Main Referenced Unit & Research Centers
GIGA-LBTD - GIGA Cancer-Tumours and development biology - ULiège (1)
Main Referenced Disciplines
Engineering, computing & technology: Multidisciplinary, general & others (28)
Biochemistry, biophysics & molecular biology (4)
Life sciences: Multidisciplinary, general & others (3)
Human health sciences: Multidisciplinary, general & others (2)
Materials science & engineering (1)

Publications (total 38)

The most downloaded
223 downloads
Bekisz, S. (2018). Insulin sensitivity testing : Mode-based subcutaneous-oral sensitivity testing [Master’s dissertation, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/238130 https://hdl.handle.net/2268/238130

The most cited

64 citations (OpenAlex)

Bekisz, S., & Geris, L. (October 2020). Cancer modeling: From mechanistic to data-driven approaches, and from fundamental insights to clinical applications. Journal of Computational Science, 46 (101198). doi:10.1016/j.jocs.2020.101198 https://hdl.handle.net/2268/260763

Bekisz, S., Lambert, C., Centonze, P., Noël, A., Dubuc, J.-E., Feyereisen, E., Breuer, N., Henrotin, Y., & Geris, L. (10 October 2025). Decoding Lymphatic Contributions to Synovial Inflammation in Osteoarthritis [Poster presentation]. ICRS World Congress, Boston, United States.
Peer reviewed

Comeliau, L., Bekisz, S., Pirlot, Z., Noël, A., & Geris, L. (30 September 2025). Modeling lymphatic capillary remodeling with agent-based simulations and a microfluidic in vitro model [Poster presentation]. Biennial European Cell Mechanics Meeting (CellMech), Leuven, Belgium.
Peer reviewed

Bekisz, S. (12 September 2025). Practical Insights Into In Vitro–In Silico Integration In Lymphatic Biology [Paper presentation]. GIGA Day.

Comeliau, L., Bekisz, S., Pirlot, Z., Noël, A., & Geris, L. (10 September 2025). Investigation of lymphatic endothelial cell sprouting behavior in pathological conditions through a combined in vitro - in silico approach [Poster presentation]. Belgium-Netherlands Vascular Biology Conference, Leuven, Belgium.
Peer reviewed

Comeliau, L., Bekisz, S., Pirlot, Z., Noël, A., & Geris, L. (09 June 2025). Modeling lymphatic capillary remodeling with agent-based simulations and a microfluidic in vitro model [Poster presentation]. MPS World Summit, Brussels, Belgium.
Peer reviewed

Bekisz, S. (2025). Integrated in vitro and in silico lymphangiogenesis : Development and use of emerging tools to generate mechanistic insights into lymphangiogenic sprouting [Doctoral thesis, ULiège - University of Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/328129

Graïne, Y., Maia Ladeira, L. C., Bekisz, S., & Geris, L. (15 April 2025). Deciphering NOTCH-Reelin Crosstalk: A Boolean Modeling Approach to Cell Fate Regulation during Lymphangiogenesis [Poster presentation]. 9th Disease Maps Community Meeting, Leuven, Belgium.
Peer reviewed

Pirson, S.* , Gautier-Isola, M.* , Baudin, L., Rouaud, L., Vanwynsberghe, A., Deroye, J., Bekisz, S., Gucciardo, F., LEBEAU, A., Buntinx, F., Ivanova, E., Staumont, B., Blacher, S., Gilles, C.* , & Noël, A.*. (27 February 2025). AXL promotes lymphangiogenesis by amplifying VEGF-C-mediated AKT pathway. Cellular and Molecular Life Sciences, 82 (1), 95. doi:10.1007/s00018-024-05542-3
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Lowette, C., Ivanova, E., Bekisz, S., Comeliau, L., Martin, M., & Noël, A. (29 January 2025). Is there a relationship between uPARAP and the cytoskeleton? [Poster presentation]. Televie Seminar 2025, Liège, Belgium.

Pottier, C., Montero-Ruiz, L., Jehay, R., Wery, C., Baiwir, D., Mazzucchelli, G., Bekisz, S., Thissen, R., Josse, C., Rorive, A., Gofflot, S., Dahmani, A., Morisset, L., Collignon, J., Delvenne, P., Marangoni, E., Noël, A., Jerusalem, G., & Sounni, N. E. (2025). Targeting ferroptosis resistance resensitizes metastatic HR+HER2- breast cancer cells to palbociclib-hormone therapy. Cancer Communications. doi:10.1002/cac2.12646
Peer Reviewed verified by ORBi

Comeliau, L., Bekisz, S., Noël, A., & Geris, L. (21 November 2024). In vitro and in silico lymphatic capillaries engineering [Paper presentation]. Belgium Symposium on Tissue Engineering - BSTE 2024, Leuven, Belgium.
Peer reviewed

Pirson, S., Gautier, M., Baudin, L., Rouaud, L., Vanwynsberghe, A., Deroye, J., Bekisz, S., Gucciardo, F., Lebeau, A., Staumont, B., Blacher, S., Gilles, C., & Noël, A. (05 March 2024). AXL promotes lymphangiogenesis by amplifying VEGF-C-mediated PI3K/AKT pathway [Poster presentation]. Gordon Research Conference and Seminar on Lymphatics, Ventura, United States - California.
Peer reviewed

Bekisz, S., Gautier, M., Comeliau, L., Paquay, A., Mead, T., Bentley, K., Noël, A., & Geris, L. (04 March 2024). Investigation of lymphatic endothelial cell sprouting behavior in pathological conditions through a combined in vitro - in silico approach [Poster presentation]. GRC Lymphatics, Ventura, United States.
Peer reviewed

Bekisz, S., Gautier, M., Comeliau, L., Paquay, A., Mead, T., Bentley, K., Noël, A., & Geris, L. (02 March 2024). Investigation of lymphatic endothelial cell sprouting behavior in pathological conditions through a combined in vitro - in silico approach [Poster presentation]. GRS Lymphatics, Ventura, United States.
Peer reviewed

Bekisz, S. (26 January 2024). An introduction to biomedical engineering and mathematical/computational modelling in biology [Paper presentation]. GIGA Cancer Seminar, Liège, Belgium.

Comeliau, L., Bekisz, S., Paquay, A., Noël, A., & Geris, L. (17 November 2023). Development of enabling technologies to investigate the interactions between lymphangiogenesis and inflammation [Poster presentation]. National Day on Biomedical Engineering, Brussels, Belgium.
Peer reviewed

Comeliau, L.* , Bekisz, S.* , Paquay, A., Noël, A., & Geris, L. (29 September 2023). Combined data-driven in silico approaches and in vitro validation to investigate lymphatic endothelial cell behavior in pathological conditions [Poster presentation]. Belgian Day on Digital Twins in Healthcare.
Peer reviewed
* These authors have contributed equally to this work.

Bekisz, S., Gautier, M., Mead, T., Bentley, K., Noël, A., & Geris, L. (06 July 2023). Investigation of lymphangiogenic sprouting through in vitro and in silico approaches [Poster presentation]. EVBO Summer School, Barcelona, Spain.
Peer reviewed

Comeliau, L., Bekisz, S., Paquay, A., Noël, A., & Geris, L. (05 July 2023). Development of enabling technologies to investigate the interactions between lymphangiogenesis and inflammation [Poster presentation]. European Vascular Biology Organisation (EVBO) Summer School, Barcelone, Spain.
Peer reviewed

Bekisz, S.* , Comeliau, L.* , Paquay, A., Noël, A., & Geris, L. (19 June 2023). Combining mechanistic and inferred network construction approaches to investigate lymphatic endothelial cell behavior in pathological conditions [Poster presentation]. Conference Systems Biology of Human Diseases (SBHD) 2023, Berlin, Germany.
Peer reviewed
* These authors have contributed equally to this work.

Pirson, S., Gautier, M., Baudin, L., Rouaud, L., Vanwynsberghe, A., Deroye, J., Bekisz, S., Gucciardo, F., Lebeau, A., Staumont, B., Blacher, S., Gilles, C., & Noël, A. (14 June 2023). Identification of a new actor involved in lymphangiogenesis processes [Poster presentation]. Lymphatic Forum 2023, Banff, Canada.
Peer reviewed

Bekisz, S., Gautier, M., Mead, T., Bentley, K., Noël, A., & Geris, L. (31 October 2022). Investigation of the role of Dll4–Notch and uPARAP in lymphangiogenic sprouts through in vitro and in silico approaches [Poster presentation]. GRC Lymphatics, Lucca, Italy.
Peer reviewed

Bekisz, S., Gautier, M., Mead, T., Bentley, K., Noël, A., & Geris, L. (29 October 2022). Investigation of the role of Dll4–Notch and uPARAP in lymphangiogenic sprouts through in vitro and in silico approaches [Poster presentation]. GRS Lymphatics, Lucca, Italy.
Peer reviewed

Bekisz, S., Gautier, M., Mead, T., Bentley, K., Noël, A., & Geris, L. (20 September 2022). An agent-based model to investigate the role of Dll4 – Notch and uPARAP in lymphangiogenic sprouts [Poster presentation]. 12th European Conference on Mathematical and Theoretical Biology, Heidelberg, Germany.
Peer reviewed

Bekisz, S., Gautier, M., Mead, T., Bentley, K., Noël, A., & Geris, L. (07 September 2022). Computational insights on the roles of Dll4 – Notch and uPARAP in lymphangiogenic sprouts [Paper presentation]. VPH2022 - Virtual Physiological Human Conference, Porto, Portugal.
Peer reviewed

Bekisz, S., Gautier, M., Mead, T., Bentley, K., Noël, A., & Geris, L. (19 June 2022). Investigation of the role of Dll4–Notch and uPARAP in lymphangiogenic sprouts through agent-based modeling [Paper presentation]. Conference SBHD 2022, Nashville, United States.
Peer reviewed

Bekisz, S., Gautier, M., Thomas Mead, Katie Bentley, Noël, A., & Geris, L. (19 June 2022). Investigation of the role of Dll4–Notch and uPARAP in lymphangiogenic sprouts through agent-based modeling [Poster presentation]. Conference SBHD 2022, Nashville, United States.
Peer reviewed

Bekisz, S., Baudin, L., Buntinx, F., Noël, A., & Geris, L. (16 March 2022). In Vitro, In Vivo, and In Silico Models of Lymphangiogenesis in Solid Malignancies. Cancers, 14 (6), 1525. doi:10.3390/cancers14061525
Peer Reviewed verified by ORBi

Bekisz, S., Noël, A., & Geris, L. (06 July 2021). IN SILICO LYMPHANGIOGENESIS : From a simple mathematical model of receptor trafficking in LECs to the experimentally characterised influence of uPARAP [Poster presentation]. SBHD.
Peer reviewed

Bekisz, S. (04 March 2021). In silico Lymphangiogenesis : Development of new tools to generate novel insights in the fundamental mechanisms regulating lymphangiogenesis [Paper presentation]. GIGA Cancer Seminar, Liège, Belgium.

Bekisz, S., & Geris, L. (October 2020). Cancer modeling: From mechanistic to data-driven approaches, and from fundamental insights to clinical applications. Journal of Computational Science, 46 (101198). doi:10.1016/j.jocs.2020.101198
Peer Reviewed verified by ORBi

Bekisz, S., Noël, A., & Geris, L. (August 2020). In silico lymphangiogenesis : Development of a mathematical model of receptor trafficking in lymphatic endothelial cells [Poster presentation]. Virtual Physiological Human Conference.

Bekisz, S., Holder-Pearson, L., Chase, J. G., & Desaive, T. (2020). In silico validation of a new model-based oral-subcutaneous insulin sensitivity testing through Monte Carlo sensitivity analyses. Biomedical Signal Processing and Control, 61 (102030). doi:10.1016/j.bspc.2020.102030
Peer Reviewed verified by ORBi

Bekisz, S., Morfoisse, F., Noël, A., & Geris, L. (27 November 2019). Computational and mathematical lymphangiogenesis : Development of an intracellular network model in lymphatic endothelial cells [Poster presentation]. NCBME.
Peer reviewed

Bekisz, S., Morfoisse, F., Noël, A., & Geris, L. (November 2019). In silico lymphangiogenesis : Development of an intracellular network model of receptor trafficking and signaling pathway in lymphatic endothelial cells [Poster presentation]. International Conference of Systems Biology, Okinawa, Japan.

Bekisz, S., Morfoisse, F., Noël, A., & Geris, L. (May 2019). In silico lymphangiogenesis : Development of new tools to generate novel insights in the fundamental mechanisms regulating lymphangiogenesis [Poster presentation]. Conference SBHD 2019, Berlin, Germany.
Peer reviewed

Bekisz, S. (2018). Insulin sensitivity testing : Mode-based subcutaneous-oral sensitivity testing [Master’s dissertation, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/238130

Holder-Pearson, L., Bekisz, S., Knopp, J., Docherty, P., Chase, J. G., & Desaive, T. (2018). Model-based Modified OGTT Insulin Sensitivity Test Design. IFAC-PapersOnLine, 51 (27), 86-91. doi:10.1016/j.ifacol.2018.11.662
Peer Reviewed verified by ORBi

Contact ORBi