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Gatot Jean-Stéphane

Département des sciences cliniques

See author's contact details
Main Referenced Co-authors
Burny, Arsène  (15)
Kettmann, Richard  (12)
Portetelle, Daniel  (10)
Willems, Luc  (10)
Van Lint, Carine (8)
Main Referenced Keywords
Humans (6); Female (3); Animals (2); Noninvasive Prenatal Testing (2); Pregnancy (2);
Main Referenced Unit & Research Centers
GIGA‐R - Giga‐Research - ULiège [BE] (1)
Giga-Signal Transduction - ULiège [BE] (1)
Main Referenced Disciplines
Genetics & genetic processes (12)
Biochemistry, biophysics & molecular biology (7)
Veterinary medicine & animal health (4)
Animal production & animal husbandry (3)
Laboratory medicine & medical technology (2)

Publications (total 34)

The most downloaded
2038 downloads
Chau, T.-L., Gioia, R., GATOT, J.-S., Patrascu, F. A., Carpentier, I., Chapelle, J.-P., O'Neill, L., Beyaert, R., Piette, J., & Chariot, A. (2008). Are the IKKs and IKK-related kinases TBK1 and IKK-ε similarly activated ? Trends in Biochemical Sciences, 33, 171-180. doi:10.1016/j.tibs.2008.01.002 https://hdl.handle.net/2268/3645

The most cited

216 citations (Scopus®)

Reuse, S., Calao, M., Kabeya, K., Guiguen, A., GATOT, J.-S., Quivy, V., Vanhulle, C., Lamine, A., Vaira, D., Demonte, D., Martinelli, V., Veithen, E., Cherrier, T., Avettand, V., Poutrel, S., Piette, J., de Launoit, Y., Moutschen, M., Burny, A., ... Van Lint, C. (2009). Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection. PLoS ONE, 4 (6), 6093. doi:10.1371/journal.pone.0006093 https://hdl.handle.net/2268/28447

van Riel, M., Brison, N., Baetens, M., Blaumeiser, B., BOEMER, F., Bourlard, L., BULK, S., De Leener, A., Désir, J., Devriendt, K., Dheedene, A., Duquenne, A., Fieremans, N., Fieuw, A., GATOT, J.-S., GRISART, B., Janssens, S., Khudashvili, N., Lannoo, L., ... Janssens, K. (2021). Performance and Diagnostic Value of Genome-Wide Noninvasive Prenatal Testing in Multiple Gestations. Obstetrics and Gynecology, 137 (6), 1102-1108. doi:10.1097/AOG.0000000000004385
Peer Reviewed verified by ORBi

Van Den Bogaert, K., Lannoo, L., Brison, N., Gatinois, V., Baetens, M., Blaumeiser, B., BOEMER, F., Bourlard, L., Bours, V., De Leener, A., De Rademaeker, M., Désir, J., Dheedene, A., Duquenne, A., Fieremans, N., Fieuw, A., GATOT, J.-S., Grisart, B., Janssens, K., ... Vermeesch, J. R. (2021). Outcome of publicly funded nationwide first-tier noninvasive prenatal screening. Genetics in medicine : official journal of the American College of Medical Genetics, 23 (6), 1137-1142. doi:10.1038/s41436-021-01101-4
Peer reviewed

Muys, J., Jacquemyn, Y., Blaumeiser, B., Bourlard, L., Brison, N., BULK, S., Chiarappa, P., De Leener, A., De Rademaeker, M., Désir, J., Destrée, A., Devriendt, K., Dheedene, A., Duquenne, A., Fieuw, A., Fransen, E., GATOT, J.-S., JAMAR, M., Janssens, S., ... Janssens, K. (2020). Prenatally detected copy number variants in a national cohort: A postnatal follow-up study. Prenatal Diagnosis. doi:10.1002/pd.5751
Peer Reviewed verified by ORBi

JAMAR, M., MENTEN, C., GRISART, B., & GATOT, J.-S. (September 2018). Trisomie 9 détectée en DPNI : à propos de deux cas de mosaïcisme [Poster presentation]. XXIVe Colloque Association des Cytogénéticiens de Langue Française (ACLF), Saint-Malo, France.

Muys, J., Blaumeiser, B., Jacquemyn, Y., Bandelier, C., Brison, N., BULK, S., Chiarappa, P., COURTENS, W., De Leener, A., De Rademaeker, M., Desir, J., Destree, A., Devriendt, K., Dheedene, A., Fieuw, A., Fransen, E., GATOT, J.-S., Holmgren, P., JAMAR, M., ... Janssens, K. (2018). The BElgian PREnatal MicroArray (BEMAPRE) database: A systematic nationwide repository of fetal genomic aberrations. Prenatal Diagnosis. doi:10.1002/pd.5373
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Kumar, A., Abbas, W., Colin, L., Khan, K. A., Bouchat, S., Varin, A., Larbi, A., GATOT, J.-S., Kabeya, K., Vanhulle, C., Delacourt, N., Pasquereau, S., Coquard, L., Borch, A., Konig, R., Clumeck, N., De Wit, S., Rohr, O., Rouzioux, C., ... Herbein, G. (2016). Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line. Scientific Reports, 6, 24090. doi:10.1038/srep24090
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Kumar, A., Abbas, W., Bouchat, S., GATOT, J.-S., Pasquereau, S., Kabeya, K., Clumeck, N., De Wit, S., Van Lint, C., & Herbein, G. (2016). Limited HIV-1 Reactivation in Resting CD4+ T cells from Aviremic Patients under Protease Inhibitors. Scientific Reports, 6, 38313. doi:10.1038/srep38313
Peer Reviewed verified by ORBi

VAN LINTHOUT, C., EMONARD, V., GATOT, J.-S., CAPELLE, X., Kridelka, F., Emonts, P., & Seghaye, M.-C. (2016). Prenatal diagnosis of a terminal chromosome 1 (q42-q44) deletion : original case report and review of the literature. Facts, Views and Vision in Obgyn, 8 (2), 101-103.
Peer Reviewed verified by ORBi

Bouchat, S., Delacourt, N., Kula, A., DARCIS, G., Van Driessche, B., Corazza, F., GATOT, J.-S., Melard, A., Vanhulle, C., Kabeya, K., Pardons, M., Avettand-Fenoel, V., Clumeck, N., De Wit, S., Rohr, O., Rouzioux, C., & Van Lint, C. (2016). Sequential treatment with 5-aza-2'-deoxycytidine and deacetylase inhibitors reactivates HIV-1. EMBO Molecular Medicine. doi:10.15252/emmm.201505557
Peer Reviewed verified by ORBi

Chau, T.-L., Göktuna, S., Rammal, A., Casanova Bustos, T. R., Duong, H. Q., GATOT, J.-S., Close, P., Dejardin, E., Desmecht, D., Shostak, K., & Chariot, A. (2015). A role for APPL1 in tlr3/4-dependent TBK1 and IKKε activation in macrophages. Journal of Immunology. doi:10.4049/jimmunol.1401614
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DARCIS, G., Kula, A., Bouchat, S., Fujinaga, K., Corazza, F., Ait-Ammar, A., Delacourt, N., Melard, A., Kabeya, K., Vanhulle, C., Van Driessche, B., GATOT, J.-S., Cherrier, T., Pianowski, L. F., Gama, L., Schwartz, C., Vila, J., Burny, A., Clumeck, N., ... Van Lint, C. (2015). An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression. PLoS Pathogens, 11 (7), 1005063. doi:10.1371/journal.ppat.1005063
Peer Reviewed verified by ORBi

BULK, S., PIERQUIN, G., GAILLEZ, S., GATOT, J.-S., CABERG, J.-H., & Bours, V. (07 February 2014). Evaluation of the distal 22q11 deletion syndrome. A highly variable phenotype [Poster presentation]. 14th Belgium Society of Human Genetics Meeting.

DARCIS, G., Kula, A., Bouchat, S., Kabeya, K., Delacourt, N., Vanhulle, C., GATOT, J.-S., VAIRA, D., Burny, A., Clumeck, N., Rohr, O., MOUTSCHEN, M., Corrazza, F., Rouzioux, C., De Wit, S., & Van Lint, C. (2014). Synergistic activation of HIV-1 expression by compounds targeting the positive transcription elongation factor b (P-TEFb) and by inducers of the NF-kB signaling pathway [Paper presentation]. 20th AIDS international conference, Melbourne, Australia.

DARCIS, G., Kula, A., Bouchat, S., Kabeya, K., Delacourt, N., Vanhulle, C., GATOT, J.-S., VAIRA, D., Burny, A., Herbein, G., Clumeck, N., Rohr, O., MOUTSCHEN, M., Rouzioux, C., De Wit, S., & Van Lint, C. (2013). Synergistic activation of HIV-1 expression by compounds targeting the positive transcription elongation factor b (P-TEFb) and by inducers of the NF-B signaling pathway [Paper presentation]. First annual meeting Belgian Society for Virology.

DARCIS, G., Kula, A., Bouchat, S., Kabeya, K., Delacourt, N., Vanhulle, C., GATOT, J.-S., VAIRA, D., Burny, A., Herbein, G., Clumeck, N., Rohr, O., MOUTSCHEN, M., Rouzioux, C., De Wit, S., & Van Lint, C. (2013). Synergistic activation of HIV-1 expression by compounds targeting the positive transcription elongation factor b (P-TEFb) and by inducers of the NF-B signaling pathway [Paper presentation]. 14th European AIDS Conference (EACS), Brussels.

Bouchat, S., GATOT, J.-S., Kabeya, K., Cardona, C., Colin, L., Herbein, G., De Wit, S., Clumeck, N., Lambotte, O., Rouzioux, C., Rohr, O., & Van Lint, C. (2012). Histone methyltransferase inhibitors induce HIV-1 recovery in resting CD4(+) T cells from HIV-1-infected HAART-treated patients. AIDS, 26 (12), 1473-82. doi:10.1097/QAD.0b013e32835535f5
Peer Reviewed verified by ORBi

Simonis, N., Rual, J.-F., Lemmens, I., Boxus, M., Hirozane-Kishikawa, T., GATOT, J.-S., Dricot, A., Hao, T., Vertommen, D., Legros, S., Daakour, S., Klitgord, N., Martin, M., Willaert, J.-F., Dequiedt, F., Navratil, V., Cusick, M. E., Burny, A., Van Lint, C., ... Twizere, J.-C. (2012). Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses. Retrovirology, 9, 26. doi:10.1186/1742-4690-9-26
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Legros, S., Boxus, M., GATOT, J.-S., Van Lint, C., Kruys, V., Kettmann, R., Twizere, J.-C., & Dequiedt, F. (2011). The HTLV-1 Tax protein inhibits formation of stress granules by interacting with histone deacetylase 6. Oncogene. doi:10.1038/onc.2011.120
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Reuse, S., Calao, M., Kabeya, K., Guiguen, A., GATOT, J.-S., Quivy, V., Vanhulle, C., Lamine, A., Vaira, D., Demonte, D., Martinelli, V., Veithen, E., Cherrier, T., Avettand, V., Poutrel, S., Piette, J., de Launoit, Y., Moutschen, M., Burny, A., ... Van Lint, C. (2009). Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection. PLoS ONE, 4 (6), 6093. doi:10.1371/journal.pone.0006093
Peer Reviewed verified by ORBi

Tanaka, T., Legat, A., Adam, E., Steuve, J., GATOT, J.-S., Vandenbranden, M., Ulianov, L., Lonez, C., Ruysschaert, J.-M., Muraille, E., Tuynder, M., Goldman, M., & Jacquet, A. (2008). DiC14-amidine cationic liposomes stimulate myeloid dendritic cells through Toll-like receptor 4. European Journal of Immunology, 38 (5), 1351-7. doi:10.1002/eji.200737998
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Chau, T.-L., Gioia, R., GATOT, J.-S., Patrascu, F. A., Carpentier, I., Chapelle, J.-P., O'Neill, L., Beyaert, R., Piette, J., & Chariot, A. (2008). Are the IKKs and IKK-related kinases TBK1 and IKK-ε similarly activated ? Trends in Biochemical Sciences, 33, 171-180. doi:10.1016/j.tibs.2008.01.002
Peer Reviewed verified by ORBi

Gioia, R., GATOT, J.-S., Chau, T.-L., Warnier, M., Chapelle, J.-P., Piette, J., Dejardin, E., & Chariot, A. (December 2007). Insight into the TBK1/IKK-dependent signalling pathways required in innate immunity through identification of the TANK/I-TRAF interactome [Poster presentation]. Journée Télévie, ULB GOsselies, Belgium.

GATOT, J.-S., Gioia, R., Chau, T.-L., Patrascu, F. A., Warnier, M., Close, P., Chapelle, J.-P., Muraille, E., Brown, K., Siebenlist, U., Piette, J., Dejardin, E., & Chariot, A. (26 October 2007). Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKK epsilon-dependent lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF. Journal of Biological Chemistry, 282 (43), 31131-31146. doi:10.1074/jbc.M701690200
Peer Reviewed verified by ORBi

GATOT, J.-S., Gioia, R., Chau, T.-L., Warnier, M., Chapelle, J.-P., Merville, M.-P., Brown, K., Siebenlist, U., Muraille, E., Dejardin, E., Piette, J., & Chariot, A. (March 2007). Polyubiquitination of the scaffold protein tank/I-traf: implications for the TLR-mediated signalling pathways [Poster presentation]. Colloque "Chromatin Dynamics and Epigenetics" Société belge de biologie cellulaire et du développement, Liège, Belgium.

GATOT, J.-S., Callebaut, I., Van Lint, C., Demonte, D., Kekhofs, P., Portetelle, D., Burny, A., Willems, L., & Kettmann, R. (2002). Interacting surface of the receptor-binding domain. In Société Belge de Biochimie et de Biologie moléculaire (pp. 74).

GATOT, J.-S., Kerkhofs, P., Burny, A., Portetelle, D., Willems, L., & Kettmann, R. (2001). A critical cysteine residue of bovine leukemia virus SU protein interacts with zinc and plays a role in viral infectivity. In The 2001 meeting on Retroviruses (pp. 181).
Peer reviewed

Willems, L., Burny, A., Collete, D., Dangoisse, O., Dequiedt, F., GATOT, J.-S., Kerkhofs, P., Lefebvre, L., Merezak, C., Peremans, T., Portetelle, D., Twizere, J.-C., & Kettmann, R. (2000). Genetic Determinants Of Bovine Leukemia Virus Pathogenesis. AIDS Research and Human Retroviruses, 16 (16), 1787-95. doi:10.1089/08892220050193326
Peer Reviewed verified by ORBi

Kerkhofs, P., GATOT, J.-S., Knapen, K., Mammerickx, M., Burny, A., Portetelle, D., Willems, L., & Kettmann, R. (2000). Long-Term Protection Against Bovine Leukaemia Virus Replication In Cattle And Sheep. Journal of General Virology, 81, 957-963. doi:10.1099/0022-1317-81-4-957
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GATOT, J.-S., Callebaut, I., Mornon, J.-P., Portetelle, D., Burny, A., Kerkhofs, P., Kettmann, R., & Willems, L. (1999). Implication de la protéine transmembranaire d’enveloppe du virus de la leucémie bovine dans la fusion cellulaire et l’infectivité virale. In Séminaire de la Recherche Télévie (pp. 12).

Willems, L., Burny, A., Dangoisse, O., Collete, D., Dequiedt, F., GATOT, J.-S., Kerkhofs, P., Lefebvre, L., Merezak, C., Portetelle, D., Twizere, J.-C., & Kettmann, R. (1999). Bovine leukemia virus as a model for human T-cell leukemia virus. Current Topics in Virology.
Peer reviewed

GATOT, J.-S., Callebaut, I., Mornon, J., Portetelle, D., Burny, A., Kerkhofs, P., Kettmann, R., & Willems, L. (1998). Conservative Mutations In The Immunosuppressive Region Of The Bovine Leukemia Virus Transmembrane Protein Affect Fusion But Not Infectivity In Vivo. Journal of Biological Chemistry, 273 (21), 12870-12880. doi:10.1074/jbc.273.21.12870
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Burny, A., Bex, F., Dequiedt, F., Adam, E., GATOT, J.-S., Kerkhofs, P., Kettmann, R., Portetelle, D., Van Den Broeke, A., & Willems, L. (1998). Leukemia Viruses. In Encyclopedia of Immunology. Elsevier.
Peer reviewed

GATOT, J.-S., Kettmann, R., Callebaut-Mornon, I., Portetelle, D., Kerkhofs, P., Burny, A., & Willems, L. (1997). Mutations in the immunosuppressive peptide of bovine leukema virus affect fusion and infectivity in vivo. Virus Research, 47 (2-Special Issue), 103.
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Willems, L., GATOT, J.-S., Mammerickx, M., Portetelle, D., Burny, A., Kerkhofs, P., & Kettmann, R. (1995). The Yxxl Signaling Motifs Of The Bovine Leukemia-Virus Transmembrane Protein Are Required For In-Vivo Infection And Maintenance Of High Viral Loads. Journal of Virology, 69 (7), 4137-4141. doi:10.1128/jvi.69.7.4137-4141.1995
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