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Demelenne Alice

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Main Referenced Co-authors
Fillet, Marianne  (31)
Servais, Anne-Catherine  (27)
Gou, Marie-Jia  (11)
Nys, Gwenaël  (11)
Crommen, Jacques  (10)
Main Referenced Keywords
Capillary electrophoresis (5); Capillary zone electrophoresis mass spectrometry (4); Mass spectrometry (3); proteomics (3); Analytical Chemistry (2);
Main Referenced Unit & Research Centers
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (17)
Giga Neurosciences - ULiège [BE] (2)
Centre Interfacultaire de Recherche du Médicament - CIRM (1)
College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada (1)
Main Referenced Disciplines
Pharmacy, pharmacology & toxicology (30)
Biochemistry, biophysics & molecular biology (3)

Publications (total 33)

The most downloaded
155 downloads
Demelenne, A., Gou, M.-J., Nys, G., Parulski, C., Crommen, J., Servais, A.-C., & Fillet, M. (2020). Evaluation of Hydrophilic Interaction Liquid Chromatography, Capillary Zone Electrophoresis and Drift Tube Ion-Mobility Quadrupole Time Of Flight mass spectrometry for the characterization of phosphodiester and phosphorothioate oligonucleotides. Journal of Chromatography. A. doi:10.1016/j.chroma.2019.460716 https://hdl.handle.net/2268/242526

The most cited

28 citations (OpenCitations)

Demelenne, A., Gou, M.-J., Nys, G., Parulski, C., Crommen, J., Servais, A.-C., & Fillet, M. (2020). Evaluation of Hydrophilic Interaction Liquid Chromatography, Capillary Zone Electrophoresis and Drift Tube Ion-Mobility Quadrupole Time Of Flight mass spectrometry for the characterization of phosphodiester and phosphorothioate oligonucleotides. Journal of Chromatography. A. doi:10.1016/j.chroma.2019.460716 https://hdl.handle.net/2268/242526

Ghassemi, M., Demelenne, A., Crommen, J., Servais, A.-C., & Fillet, M. (01 February 2023). Application of cyclodextrins in capillary electrophoresis to improve stereo- and chemo selectivity of phosphorothioate oligonucleotides [Poster presentation]. CIRM Day, Liege, Belgium.
Peer reviewed

Ghassemi K, M., Demelenne, A., Crommen, J., Servais, A.-C., & Fillet, M. (02 August 2022). Improvement of chemo- and stereoselectivity for phosphorothioate oligonucleotides in capillary electrophoresis by addition of cyclodextrins. Journal of Chromatography. A, 1676, 463270. doi:10.1016/j.chroma.2022.463270
Peer Reviewed verified by ORBi

Demelenne, A., Ben Yahia, A., Ghassemi, L., Lempereur Delphine, Crommen, J., Servais, A.-C., & Fillet, M. (03 July 2022). Biosimilar comparability of a monoclonal antibody and a FC-Fusion protein by SEC, CGE and RPLC [Poster presentation]. 38th International Symposium on Microscale Separations and Bioanalysis (MSB 2022), Liege, Belgium.
Peer reviewed

Demelenne, A., Nys, G., Nix, C., Fjeldsted, J. C., Crommen, J., & Fillet, M. (25 January 2022). Separation of phosphorothioated oligonucleotide diastereomers using multiplexed drift tube ion mobility mass spectrometry. Analytica Chimica Acta, 1191, 339297. doi:10.1016/j.aca.2021.339297
Peer Reviewed verified by ORBi

Demelenne, A., Servais, A.-C., Crommen, J., & Fillet, M. (16 August 2021). Analytical techniques currently used in the pharmaceutical industry for the quality control of RNA-based therapeutics and ongoing developments. Journal of Chromatography. A, 1651, 462283. doi:10.1016/j.chroma.2021.462283
Peer Reviewed verified by ORBi

Demelenne, A., Ben Yahia, A., Lempereur, D., Crommen, J., Servais, A.-C., Fradi, I., & Fillet, M. (2021). Comparison of Three Complementary Analytical Techniques for the Evaluation of the Biosimilar Comparability of a Monoclonal Antibody and an Fc-Fusion Protein. Frontiers in Chemistry, 9, 782099. doi:10.3389/fchem.2021.782099
Peer Reviewed verified by ORBi

Gou, M.-J., Nys, G., COBRAIVILLE, G., Demelenne, A., Servais, A.-C., CAERS, J., & Fillet, M. (30 September 2020). CE-MS/MS: investigation of two hyphenating approaches for proteomics studies in the context of multiple myeloma [Paper presentation]. 36th International Symposium on Microscale Separations and Bioanalysis, Saint-Malo, France.

Gou, M.-J., Nys, G., COBRAIVILLE, G., Demelenne, A., Servais, A.-C., Caers, J., & Fillet, M. (September 2020). Capillary electrophoresis tandem mass spectrometry for proteomics in the context of multiple myeloma: investigation of two hyphenating approaches [Paper presentation]. 36th International Symposium on Microscale Separations and Bioanalysis.

Gou, M.-J., Nys, G., COBRAIVILLE, G., Demelenne, A., Servais, A.-C., & Fillet, M. (2020). Hyphenation of capillary zone electrophoresis with mass spectrometry for proteomic analysis: Optimization and comparison of two coupling interfaces. Journal of Chromatography. A. doi:10.1016/j.chroma.2020.460873
Peer Reviewed verified by ORBi

Demelenne, A., Gou, M.-J., Nys, G., Parulski, C., Crommen, J., Servais, A.-C., & Fillet, M. (2020). Evaluation of Hydrophilic Interaction Liquid Chromatography, Capillary Zone Electrophoresis and Drift Tube Ion-Mobility Quadrupole Time Of Flight mass spectrometry for the characterization of phosphodiester and phosphorothioate oligonucleotides. Journal of Chromatography. A. doi:10.1016/j.chroma.2019.460716
Peer Reviewed verified by ORBi

Sambon, M., Gorlova, A., Demelenne, A., Alhama-Riba, J., Coumans, B., Lakaye, B., Wins, P., Fillet, M., Anthony, D. C., Strekalova, T., & Bettendorff, L. (2020). Dibenzoylthiamine has powerful antioxidant and anti-inflammatory properties in cultured cells and in mouse models of stress and neurodegeneration. Biomedicines, 8, 361. doi:10.3390/biomedicines8090361
Peer Reviewed verified by ORBi

Gou, M.-J., Nys, G., COBRAIVILLE, G., Demelenne, A., Servais, A.-C., & Fillet, M. (11 December 2019). Proteomic analysis using capillary electrophoresis hyphenated with high resolution mass spectrometry: comparison of two coupling interfaces [Poster presentation]. 2nd Cirm Day, Liège, Belgium.

Demelenne, A., Gou, M.-J., Nys, G., Parulski, C., Servais, A.-C., & Fillet, M. (11 December 2019). Ion mobility high resolution mass spectrometry coupled to HILIC and CZE for the characterization of phosphodiester and phosphorothioate oligonucleotides [Paper presentation]. 2nd Cirm Day, Liège, Belgium.

Gachumi, G., Demelenne, A., Poudel, A., & El-Aneed, A. (29 September 2019). Development of a Fast Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method for Simultaneous Determination of Phytosterols and Tocopherols [Poster presentation]. Detection, Diagnosis, and Health Concerns of Toxic Chemical and Biological Agents, Cetraro, Italy.

Demelenne, A., Gou, M.-J., Nys, G., Parulski, C., Servais, A.-C., & Fillet, M. (17 September 2019). Quality control of therapeutic phosphorothioate oligonucleotides by hydrophilic interaction liquid chromatography coupled with ION-MOBILITY QTOF [Paper presentation]. 30 th INTERNATIONAL SYMPOSIUM ON PHARMACEUTICAL & BIOMEDICAL ANALYSIS, Tel Aviv, Israel.

Gou, M.-J., Nys, G., Demelenne, A., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (17 September 2019). Comparison of two capillary electrophoresis-mass spectrometry interfaces for proteomic analysis [Poster presentation]. 30th International Symposium on Pharmaceutical and Biomedical Analysis, Tel Aviv, Israel.

Gou, M.-J., Nys, G., Demelenne, A., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (01 September 2019). Capillary electrophoresis tandem mass spectrometry for proteomic analysis: optimization and comparison of two coupling interfaces [Poster presentation]. 26th International Symposium on Electroseparation and Liquid Phase-Separation Techniques, Toulouse, France.

Demelenne, A., Gou, M.-J., Parulski, C., Servais, A.-C., & Fillet, M. (20 May 2019). Optimisation of the separation of therapeutic phosphorothioate oligonucleotides by hydrophilic interaction liquid chromatography and capillary zone electrophoresis [Paper presentation]. 20th Forum of Pharmaceutical Sciences.

Radermecker, R., Demelenne, A., Desaive, T., & Fillet, M. (2019). Analyse des concentrations de quatre type d'insulines différentes ( humaine 100 IU/ml, aspart 100 IU/ml, lispro 200 IU/ml et glargine 300 IU/ml) provenant de trois sources différentes (pharmacie hospitalière , officine de ville , et échantillons procurés au diabétologue par les représentants de l’industrie ). . Diabetes and Metabolism.
Peer Reviewed verified by ORBi

Demelenne, A., NAPP, A., Bouillenne, F., Crommen, J., Servais, A.-C., & Fillet, M. (2019). Insulin aggregation assessment by capillary gel electrophoresis without sodium dodecyl sulfate: Comparison with size-exclusion chromatography. Talanta, 199, 457-463. doi:10.1016/j.talanta.2019.02.074
Peer Reviewed verified by ORBi

Sambon, M., NAPP, A., Demelenne, A., Vignisse, J., Wins, P., Fillet, M., & Bettendorff, L. (2019). Thiamine and benfotiamine protect neuroblastoma cells against paraquat and ß- amyloid toxicity by a coenzyme-independent mechanism. Heliyon, 5, 01710. doi:10.1016/j.heliyon.2019.e01710
Peer Reviewed verified by ORBi

Demelenne, A., Napp, A., Radermecker, R., Servais, A.-C., & Fillet, M. (19 December 2018). Quality control and aggregation follow-up of insulin formulations [Paper presentation]. First CIRM scientific day, Liège, Belgium.

Gou, M.-J., Demelenne, A., Parulski, C., Servais, A.-C., & Fillet, M. (19 December 2018). Quality control of therapeutic oligonucleotides using HILIC-UV and CZE-UV [Poster presentation]. CIRM Day, Liège, Belgium.

Nys, G., COBRAIVILLE, G., Farcas, E., Demelenne, A., Kok, M., Servais, A.-C., & Fillet, M. (October 2018). Microfluidic analytical approaches to drive drug development [Paper presentation]. In the framework of High-end Foreign Experts program, Guangzhou, China.

Demelenne, A., Gachumi, G., Poudel, A., Purves, R., Dallal Bashi, Z., & El-Aneed, A. (11 September 2018). Simple quantification of phytosterols and tocopherols using fast chromatography -Tandem mass spectrometry [Poster presentation]. the 11th International Symposium on Drug Analysis and the 29th International Symposium on Pharmaceutical and Biomedical Analysis, Leuven, Belgium.

Demelenne, A., Napp, A., Servais, A.-C., & Fillet, M. (10 September 2018). Insulin aggregation assessment by size-exclusion chromatography and capillary gel electrophoresis [Poster presentation]. the 11th International Symposium on Drug Analysis and the 29th International Symposium on Pharmaceutical and Biomedical Analysis.

Demelenne, A., NAPP, A., Servais, A.-C., & Fillet, M. (12 July 2018). Follow-up of Insulin Aggregation productions in the context of formulation quality control [Poster presentation]. Second international symposium on advanced in Pharmaceutical analysis, Lilles, France.

Nys, G., COBRAIVILLE, G., Demelenne, A., Servais, A.-C., & Fillet, M. (12 June 2018). ion mobility Q-TOF, an attractive tool for biomarker discovery and biopharmaceutical analysis [Paper presentation]. Agilent Day BELUX, Gent, Belgium.

Napp, A., Houbart, V., Demelenne, A., Merville, M.-P., Crommen, J., Dumoulin, M., Garraux, G., Servais, A.-C., & Fillet, M. (2018). Separation and determination of alpha-synuclein monomeric and oligomeric species using two electrophoretic approaches. Electrophoresis, 39 (23), 3022-3031. doi:10.1002/elps.201800224
Peer Reviewed verified by ORBi

Napp, A., Houbart, V., Demelenne, A., Servais, A.-C., & Fillet, M. (18 September 2017). Challenges in the determination of amyloid oligomeric species by two electrophoretic techniques [Poster presentation]. CE-PHARM 2017, Boston, United States.

Demelenne, A., Napp, A., Lamalle, C., Servais, A.-C., & Fillet, M. (21 June 2017). Quality control of insulin formulations: API , protamine and aggregates follow-up [Poster presentation]. The 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Prague, Czechia.

Demelenne, A., Napp, A., Servais, A.-C., & Fillet, M. (October 2016). Study of insulin aggregation by SEC and CGE [Paper presentation]. 19th Forum of Pharmaceutical Sciences, Bruxelles, Belgium.

Lamalle, C., Servais, A.-C., Demelenne, A., Crommen, J., & Fillet, M. (2016). Analysis of protamine peptides in insulin pharmaceutical formulations by capillary electrophoresis. Journal of Separation Science, 39 (6), 1189-94. doi:10.1002/jssc.201501093
Peer Reviewed verified by ORBi

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