Khurana, S., Schivo, S., Plass, J. R. M., Mersinis, N., Scholma, J., Kerkhofs, J., Zhong, L., van de Pol, J., Langerak, R., Geris, L., Karperien, M., & Post, J. N. (2021). An ECHO of Cartilage: In Silico Prediction of Combinatorial Treatments to Switch Between Transient and Permanent Cartilage Phenotypes With Ex Vivo Validation. Frontiers in Bioengineering and Biotechnology, 9, 732917. doi:10.3389/fbioe.2021.732917 Peer Reviewed verified by ORBi |
Schivo, S., Khurana, S., Govindaraj, K., Scholma, J., Kerkhofs, J., Zhong, L., Huang, X., van de Pol, J., Langerak, R., van Wijnen, A. J., Geris, L., Karperien, M., & Post, J. N. (April 2020). ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease. Cellular Signalling, 68, 109471. doi:10.1016/j.cellsig.2019.109471 Peer Reviewed verified by ORBi |
Kerkhofs, J. (2015). Chondrogenic Differentiation in the growth Plate: a Computational Modelling Approach [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/186583 |
Kerkhofs, J., & Geris, L. (11 June 2015). A semiquantitative framework for gene regulatory networks: increasing the time and quantitative resolution of Boolean networks. PLoS ONE, 10 (6), 0130033. doi:10.1371/journal.pone.0130033 Peer Reviewed verified by ORBi |
Kerkhofs, J., Leijten, J., Luyten, F., & Geris, L. (30 April 2015). In silico screening to predict chondrocyte hypertrophy using a semiquantitative gene network model [Poster presentation]. OARSI 2015. |
Kerkhofs, J. (18 June 2014). The search for a core functionality network in chondrocyte differentiation using heuristic and genetic algorithms [Paper presentation]. ECTMB 2014. |
Germain, M., Kerkhofs, J., & Geris, L. (2014). Simulation and analysis of bistability in osteochondrogenesis [Paper presentation]. ECMTB (European Conference on Mathematical and Theoretical Biology). |
Van Schepdael, A., Carlier, A., Ashbourn, J., Nica, I., Kerkhofs, J., & Geris, L. (13 September 2013). Congenital pseudarthrosis of the tibia: a mathematical approach [Paper presentation]. International Conference on Computational Bioengineering. |
Kerkhofs, J., Van Oosterwyck, H., & Geris, L. (11 September 2013). A gene regulatory network model evaluating the impact of individual factors in the hypertrophic switch [Paper presentation]. ICCB 2013. |
Germain, M., Kerkhofs, J., & Geris, L. (September 2013). Mutual inhibition and bistability: two key elements of the endochondral ossification process [Poster presentation]. ICSB 2013 Copenhagen ( The 14 th International Conference on System Biology). |
Kerkhofs, J., Van Oosterwyck, H., & Geris, L. (29 August 2013). A Gene Regulatory Network Model to Assess the Stability of the Cartilage Phenotype [Poster presentation]. ICSB 2013. |
Kerkhofs, J., & Van Oosterwyck, H. (17 June 2013). A computational Model to Assess the Contribution of Growth Factors to Phenotype Stability in Chondrocytes [Paper presentation]. TERMIS-EU 2013, Istanbul, Turkey. |
Germain, M., Kerkhofs, J., & Geris, L. (2013). MATHEMATICAL MODELING OF ENDOCHONDRAL OSSIFICATION THROUGH MUTUAL INHIBITION AND BISTABILITY [Paper presentation]. ICCB 2013 : V International Conference on Computational Bioengineering. |
Germain, M., Kerkhofs, J., & Geris, L. (2013). Modeling the effect of the interaction between BMP and Wnt in osteochondroprogenitor cells [Poster presentation]. BSTE (Belgian Symposium on Tissue Engineering). |
Kerkhofs, J., Van Oosterwyck, H., & Geris, L. (18 September 2012). A Dynamic Graph Model of Endochondral Ossification can assess the Importance of Biological Actors in Differentiation [Paper presentation]. 1st Belgian Symposium on Tissue Engineering, Leuven, Belgium. |
Kerkhofs, J., Geris, L., Bosmans, B., & Van Oosterwyck, H. (02 July 2012). Bridging the Gap: A Theoretical Model of Mechanotransduction Through ERK Signalling [Paper presentation]. 18th International Congres of the European Society of Biomechanics (ESB), Lisbon, Portugal. |
Kerkhofs, J., Roberts, S. J., Luyten, F. P., Van Oosterwyck, H., & Geris, L. (2012). Relating the Chondrocyte Gene Network to Growth Plate Morphology: From Genes to Phenotype. PLoS ONE. doi:10.1371/journal.pone.0034729 Peer Reviewed verified by ORBi |
Kerkhofs, J., Geris, L., Bosmans, B., & Van Oosterwyck, H. (2012). Coupling Cell Mechanics and Intracellular Signalling: Mechanotransduction through ERK. In J. Middleton (Ed.), The Proceedings of the 10th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering. Hotel Berlin, Berlin, Germany, April 7th – 11th, 2012 pages:0-0. ARUP. Peer reviewed |
Kerkhofs, J., Roberst, S. J., Luyten, F. P., Van Oosterwyck, H., & Geris, L. (13 June 2011). A Boolean network approach to developmental engineering [Paper presentation]. TERMIS-EU 2011, Granada, Spain. |
Kerkhofs, J., Roberts, S. J., Luyten, F. P., Van Oosterwyck, H., & Geris, L. (26 November 2010). A Boolean network model of the growth plate [Poster presentation]. Belgian Day on Biomedical Engineering, Brussels, Belgium. |
Kerkhofs, J., Roberts, S. J., Luyten, F. P., Van Oosterwyck, H., & Geris, L. (10 October 2010). A Boolean network model of the growth plate [Poster presentation]. International Conference on Systems Biology (ICSB 2010), Edinburgh, United Kingdom. |
Kerkhofs, J., Roberts, S. J., Van Oosterwyck, H., Luyten, F. P., & Geris, L. (15 September 2010). BMP signalling in growth plate chondrocytes: a Boolean modelling approach [Poster presentation]. 8th international confererence on Bone Morphogenetic Proteins, Leuven, Belgium. |