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Peixoto Paul

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Main Referenced Co-authors
Castronovo, Vincenzo  (40)
Mottet, Denis  (36)
Matheus, Nicolas  (27)
Blomme, Arnaud  (22)
Polese, Catherine  (22)
Main Referenced Keywords
Cancer (17); HDAC5 (16); Metabolism (12); Humans (7); Apoptosis (6);
Main Referenced Unit & Research Centers
Centre Interfacultaire de Recherche du Médicament - CIRM (7)
Giga-Cancer - ULiège [BE] (5)
INSERM, U837 (1)
Laboratoire de recherche sur les métastases (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (22)
Oncology (19)
Life sciences: Multidisciplinary, general & others (16)
Pharmacy, pharmacology & toxicology (10)
Laboratory medicine & medical technology (2)

Publications (total 67)

The most downloaded
582 downloads
Turtoi, A., Mottet, D., Matheus, N., Dumont, B., Peixoto, P., Hennequière, V., Deroanne, C., Colige, A., De Pauw, E., Bellahcene, A., & Castronovo, V. (2012). The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells. Angiogenesis. doi:10.1007/s10456-012-9279-8 https://hdl.handle.net/2268/133423

The most cited

101 citations (Scopus®)

Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Peulen, O., Blomme, A., Turtoi, A., Costanza, B., Smargiasso, N., Baiwir, D., Scheijen, J., Schalkwijk, C., Leenders, J., De Tullio, P., BIANCHI, E., Thiry, M., Uchida, K., Spiegel, D., Cochrane, J., ... Bellahcene, A. (2016). Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP- mediated tumor growth and metastasis. eLife. doi:10.7554/eLife.19375 https://hdl.handle.net/2268/207276

Hendrick, E., Peixoto, P., Blomme, A., Polese, C., Matheus, N., Cimino, J., Frère, A., Mouithys-Mickalad, A., Serteyn, D., Bettendorff, L., Elmoualij, B., De Tullio, P., Eppe, G., Dequiedt, F., Castronovo, V., & Mottet, D. (2017). Metabolic inhibitors accentuate the anti-tumoral effect of HDAC5 inhibition. Oncogene. doi:10.1038/onc.2017.103
Peer Reviewed verified by ORBi

Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Peulen, O., Blomme, A., Turtoi, A., Costanza, B., Smargiasso, N., Baiwir, D., Scheijen, J., Schalkwijk, C., Leenders, J., De Tullio, P., BIANCHI, E., Thiry, M., Uchida, K., Spiegel, D., Cochrane, J., ... Bellahcene, A. (2016). Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP- mediated tumor growth and metastasis. eLife. doi:10.7554/eLife.19375
Peer Reviewed verified by ORBi

Henry, A., Nokin, M.-J., Leroi, N., Lallemand, F., Lambert, J., Goffart, N., RONCARATI, P., BIANCHI, E., Peixoto, P., Blomme, A., Turtoi, A., Peulen, O., Habraken, Y., Scholtes, F., Martinive, P., Delvenne, P., Rogister, B., Castronovo, V., & Bellahcene, A. (2016). New role of osteopontin in DNA repair and impact on human glioblastoma radiosensitivity. Oncotarget. doi:10.18632/oncotarget.11483
Peer Reviewed verified by ORBi

Henry, A., Nokin, M.-J., Leroi, N., LALLEMAND, F., Lambert, J., Goffart, N., Peixoto, P., Blomme, A., BIANCHI, E., Habraken, Y., RONCARATI, P., Peulen, O., SCHOLTES, F., MARTINIVE, P., Rogister, B., Delvenne, P., Turtoi, A., Castronovo, V., & Bellahcene, A. (22 March 2016). Osteopontin predicts radiotherapy response of glioblastoma patients : new role in DNA damage repair [Paper presentation]. 3rd Symposium on small animal precision image-guided radiotherapy, Gand, Belgium.

Fahmy, K., Gonzalez, A., Arafa, M., Peixoto, P., Bellahcene, A., Turtoi, A., Delvenne, P., Thiry, M., Castronovo, V., & Peulen, O. (2016). Myoferlin plays a key role in VEGFA secretion and impacts tumor-associated angiogenesis in human pancreas cancer. International Journal of Cancer, 138, 652-663. doi:10.1002/ijc.29820
Peer Reviewed verified by ORBi

Peixoto, P.* , Blomme, A.* , Costanza, B.* , Ronca, R., Rezzola, S., Palacios, A., SCHOYSMAN, L., Boutry, S., Goffart, N., Peulen, O., Maris, P., Di Valentin, E., Hennequière, V., BIANCHI, E., Henry, A., Meunier, P., Rogister, B., MULLER, R., Delvenne, P., ... Turtoi, A. (2016). HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and PTEN: new opportunities for selected targeted therapies. Oncogene. doi:10.1038/onc.2015.506
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Eppe, G., Castronovo, V., & Mottet, D. (03 December 2015). Compensatory Metabolism Promotes Cancer Cell Adaptation to HDAC5 Silencing [Poster presentation]. Séminaires des chercheurs Télévie 2016, Gembloux, Belgium.

Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Peulen, O., Blomme, A., Turtoi, A., Costanza, B., Smargiasso, N., Baiwir, D., Leenders, J., De Tullio, P., BIANCHI, E., Thiry, M., Uchida, K., Spiegel, D., Cochrane, J., Hutton, C., De Pauw, E., ... Bellahcene, A. (29 September 2015). Methylglyoxal, a glycolysis side-product, induces Hsp90 post-translational glycation and YAP-mediated breast tumor growth and metastasis [Poster presentation]. Cancer and Metabolism Conference, Cambridge, United Kingdom.

Durieux, F., Peixoto, P., Chiavarina, B., Nokin, M.-J., Karoyan, P., Castronovo, V., & Bellahcene, A. (28 September 2015). Characterization of new carbonyl scavenger molecules and their subsequent use for cancer therapy [Poster presentation]. Cancer and Metabolism Abcam 2015 Conference, Cambridge, United Kingdom.

Henry, A., Bellahcene, A., Castronovo, V., Peixoto, P., Goffart, N., Lallemand, F., Leroi, N., Peulen, O., MARTINIVE, P., Habraken, Y., Turtoi, A., Rogister, B., & Blomme, A. (Other coll.). (10 September 2015). Osteopontin as a new target in glioblastoma progression and resistance to radiotherapy [Paper presentation]. II International Symposium on clinical and basic investigation in glioblastoma, Toledo, Spain.

Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Peulen, O., Blomme, A., Smargiasso, N., De Tullio, P., BIANCHI, E., Baiwir, D., Thiry, M., Turtoi, A., De Pauw, E., DELVENNE, P., Castronovo, V., & Bellahcene, A. (09 September 2015). Methylglyoxal, a glycolysis side-product, induces Hsp90 post-translational glycation and YAP-mediated breast tumor growth and metastasis [Poster presentation]. Metabolism in Cancer and Stromal Cells, Leuven, Belgium.

Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (11 February 2015). HDAC5 Depletion in Cancer Cells Induces an Oxidative Stress and Leads to a Metabolic Reprogramming toward Glucose and Glutamine Metabolism [Poster presentation]. Seminaires des chercheurs Télévie 2015, Bruxelles, Belgium.

Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (31 January 2015). HDAC5 Depletion in Cancer Cells Induces an Oxidative Stress and Leads to a Metabolic Reprogramming toward Glucose and Glutamine Metabolism [Poster presentation]. ABEC TUmor Metabolism and Mitochondria, Bruxelles, Belgium.

Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (27 January 2015). HDAC5 Depletion in Cancer Cells Induces an Oxidative Stress and Leads to a Metabolic Reprogramming toward Glucose and Glutamine Metabolism [Poster presentation]. Giga Cancer Day 2015 Current Advances in Medical Genetics and Genomics, Liège, Belgium.

Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Smargiasso, N., Baiwir, D., De Pauw, E., De Tullio, P., Thiry, M., Peulen, O., Turtoi, A., Castronovo, V., & Bellahcene, A. (27 January 2015). Accumulation of methylglyoxal, a glycolysis by-product modulates YAP1 transcription co-factor localization and activity in human breast cancer cells through HSP90 modification [Poster presentation]. GIGA-DAY: Current advances in medical genetics and genomics, Liège, Belgium.

Frère, A., Kawalec, M., Tempelaar, S., Peixoto, P., Hendrick, E., Peulen, O., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (2015). Impact of the Structure of Biocompatible Aliphatic Polycarbonates on siRNA Transfection Ability. Biomacromolecules. doi:10.1021/bm501676p
Peer Reviewed verified by ORBi

Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (30 September 2014). HDAC5 Depletion in Cancer Cells Induces an Oxidative Stress and Leads to a Metabolic Reprogramming toward Glucose and Glutamine Metabolism [Paper presentation]. Annual Mini symposium 2014, Liège, Belgium.

Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (25 September 2014). HDAC5 Depletion in Cancer Cells Induces an Oxidative Stress and Leads to a Metabolic Reprogramming toward Glucose and Glutamine Metabolism [Poster presentation]. Metabolism and Cancer Nice, Nice, France.

Frère, A., Tempelaar, S., Peixoto, P., Peulen, O., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (28 August 2014). Polyplex based on polycarbonate polymesr for an efficient delivery of an anti-angiogenic siRNA [Paper presentation]. Translational Nanomedicine, Angers, France.

Chiavarina, B.* , Nokin, M.-J.* , Durieux, F., BIANCHI, E., Turtoi, A., Peulen, O., Peixoto, P., Irigaray, P., Uchida, K., Belpomme, D., Delvenne, P., Castronovo, V., & Bellahcene, A. (2014). Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypes. Oncotarget. doi:10.18632/oncotarget.2121
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* These authors have contributed equally to this work.

Frère, A., Kawalec, M., Tempelaar, S., Peixoto, P., Peulen, O., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (26 May 2014). Impact of the Structure of Biocompatible Aliphatic Polycarbonate on siRNA Transfection Ability [Poster presentation]. Advanced Functional Polymers for Medicine AFPM) 2014, Liège, Belgium.

Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (19 May 2014). Glucose-dependent metabolic reprogramming in HDAC5-depleted cancer cells [Poster presentation]. Giga Cancer Day 2014 THE LYMPHATIC SYSTEM : THE BED AND BENCH POINT OF VIEWS, Liège, Belgium.

Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (25 April 2014). Glucose-dependent metabolic reprogramming in HDAC5-depleted cancer cells [Poster presentation]. Reactive Oxygen Species in Cell Metabolism 11th Meeting of the FRS-FNRS contact group on oxidative stress and anti-oxidants 210th Meeting of the Belgian Society of Biochemistry and Molecular Biology, Belgium.

Frère, A., Peixoto, P., Kawalec, M., Evrard, B., Mespouille, L., Mottet, D., & Piel, G. (April 2014). Polyplexes Targeting Angiogenesis in Cancer [Poster presentation]. 9th World Meeting on Pharmaceutics, Biopharmaceuticsand Pharmaceutical Technology, Lisbon, Portugal.

Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Castronovo, V., & Mottet, D. (01 February 2014). Complex I Mitochondrial Dysfunction in HDAC5-depleted Cancer Cells Induces Glucose-dependent Metabolic Reprogramming [Poster presentation]. Association Belge pour l'étude du cancer A.B.E.C 2014, Anvers, Belgium.

Hendrick, E., Peixoto, P., Matheus, N., Polese, C., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (27 January 2014). Complex I Mitochondrial Dysfunction in HDAC5-depleted Cancer Cells Induces Glucose-dependent Metabolic Reprogramming [Poster presentation]. Giga Day 2014, Liège, Belgium.

Matheus, N., Hansen, S., Rozet, E., Peixoto, P., Maquoi, E., LAMBERT, V., Noël, A., Frederich, M., Mottet, D., & De Tullio, P. (January 2014). An Easy, Convenient Cell and Tissue Extraction Protocol for Nuclear Magnetic Resonance Metabolomics. Phytochemical Analysis, 25, 342-349. doi:10.1002/pca.2498
Peer Reviewed verified by ORBi

Frère, A., Kawalec, M., Tempelaar, S., Peixoto, P., Peulen, O., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (2014). Polyplex Based On Polycarbonate Polymers For An Efficient Delivery Of An Anti-Angiogenic siRNA [Poster presentation]. 3rd NanoFar Autumn School, Brussels, Belgium.

Hendrick, E., Matheus, N., Peixoto, P., Polese, C., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., Elmoualij, B., De Tullio, P., Castronovo, V., & Mottet, D. (05 December 2013). HDAC5 depletion Decreases NDUFB5 Subunit of Mitochondrial Complex- I leading to Glucose-dependent Metabolic Reprogrammation [Poster presentation]. Séminaire des chercheurs Télévie 2014, Bruxelles, Belgium.

Frère, A., Kawalec, M., Peixoto, P., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (December 2013). The intracellular fate of polycarbonate Polyplexes modulates the efficacy of siRNA [Poster presentation]. 28th GTRV annual meeting, Orleans, France.

Frère, A., Peixoto, P., Mottet, D., & Piel, G. (17 October 2013). Polyplexes based on polycarbonate polymers and siRNA against HDAC7 for a targeted anti-angiogenic therapy [Paper presentation]. 17th forum of Pharmaceutical Sciences, Spa, Belgium.

Hendrick, E., Matheus, N., Peixoto, P., Polese, C., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Castronovo, V., & Mottet, D. (13 September 2013). Complexe I mitochondrial dysfunction in HDAC5 depleted cancer cells induces glucose-dependent metabolic reprogrammation [Poster presentation]. Annual Mini symposium 2013, Bruxelles, Belgium.

Peulen, O.* , Gonzalez, A.* , Peixoto, P., Turtoi, A., Mottet, D., Delvenne, P., & Castronovo, V. (11 September 2013). The Anti-Tumor Effect of HDAC Inhibition in a Human Pancreas Cancer Model Is Significantly Improved by the Simultaneous Inhibition of Cyclooxygenase 2. PLoS ONE, 8 (9), 75102. doi:10.1371/journal.pone.0075102
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Gonzalez, A., Peixoto, P., Turtoi, A., Mottet, D., Delvenne, P., Castronovo, V., & Peulen, O. (11 July 2013). Concomitant inhibition of class I HDAC and COX-2 exerts a antitumor effect in a human pancreatic cancer model [Poster presentation]. WIN2013 Symposium: "Personalized Cancer Therapy: from innovation to implemantation".

Hendrick, E., Matheus, N., Peixoto, P., Polese, C., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Castronovo, V., & Mottet, D. (17 May 2013). Mitochondrial dysfunction in HDAC5-depleted cancer cells induces glucose-dependent metabolic adaptation [Poster presentation]. GIGA-Cancer Day 2013, Liège, Belgium.

Hendrick, E., Matheus, N., Peixoto, P., Polese, C., Mouithys-Mickalad, A., Serteyn, D., Michiels, C., Castronovo, V., & Mottet, D. (02 February 2013). JNK/ROS signaling pathway is responsible for induction of autophagy in HDAC5 depleted cancer cells [Poster presentation]. Association Belge pour l'étude du cancer A.B.E.C 2013, Gand, Belgium.

Hendrick, E., Matheus, N., Peixoto, P., Polese, C., Mouithys-Mickalad, A., Serteyn, D., Castronovo, V., & Mottet, D. (29 January 2013). JNK/ROS Signaling Pathway Is Responsible for Induction of Autophagy in HDAC5 depleted Cancer Cells [Paper presentation]. Journée Scientifique des doctorants en sciences Biomédicales et Pharmaceutiques, Mons, Belgium.

Hendrick, E., Matheus, N., Peixoto, P., Polese, C., Thiry, M., Mouithys-Mickalad, A., Serteyn, D., & Castronovo, V. (28 January 2013). JNK/ROS signaling pathway is responsible for induction of autophagy in HDAC5 depleted cancer cells [Poster presentation]. Giga Day 2013, Liège, Belgium.

Turtoi, A.* , Blomme, A.* , Bellahcene, A., Gilles, C., Hennequière, V., Peixoto, P., BIANCHI, E., Noël, A., De Pauw, E., LIFRANGE, E., Delvenne, P., & Castronovo, V. (2013). Myoferlin is a key regulator of EGFR activity in breast cancer. Cancer Research, 73, 5438-5448. doi:10.1158/0008-5472.CAN-13-1142
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Martin, M., Geudens, I., Bruyr, J., Potente, M., Bleuart, A., Lebrun, M., Simonis, N., Deroanne, C., Twizere, J.-C., Soubeyran, P., Peixoto, P., Mottet, D., Janssens, V., Hofmann, W.-K., Claes, F., Carmeliet, P., Kettmann, R., Gerhardt, H., & Dequiedt, F. (2013). PP2A regulatory subunit Balpha controls endothelial contractility and vessel lumen integrity via regulation of HDAC7. EMBO Journal. doi:10.1038/emboj.2013.187
Peer Reviewed verified by ORBi

Bournine, L., Bensalem, S., Peixoto, P., Gonzalez, A., Maiza-Benabdesselam, F., Bedjou, F., Wauters, J.-N., Tits, M., Frederich, M., Castronovo, V., & Bellahcene, A. (2013). Revealing the anti-tumoral effect of Algerian Glaucium flavum roots against human cancer cells. Phytomedicine, 20 (13), 1211-1218. doi:10.1016/j.phymed.2013.06.007
Peer Reviewed verified by ORBi

Hendrick, E., Peixoto, P., Matheus, N., Polese, C., Castronovo, V., & Mottet, D. (10 December 2012). Role of HDAC5 depletion induced autophagy on cancer cell death [Poster presentation]. Séminaires des chercheurs Télévie 2013, Liège, Belgium.

Frère, A., Kawalec, M., Collard, L., Matheus, N., Peixoto, P., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (22 October 2012). Characterization and transfection experiments of polyplexes targeting HDAC7 [Poster presentation]. NanoFar Autumn School, Angers, France.

Castronovo, V., Matheus, N., Dumont, B., Peixoto, P., Hennequière, V., Deroanne, C., Colige, A., De Pauw, E., Bellahcene, A., Mottet, D., & Turtoi, A. (21 April 2012). The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells [Paper presentation]. Experimental Biology 2012, SAN DIEGO, United States.

Peixoto, P., Matheus, N., Polese, C., gonzalez, A., Castronovo, V., & Mottet, D. (04 February 2012). HDAC5 is required for maintenance of pericentric heterochromatin and controls cell cycle progression of human cancer cells [Poster presentation]. Belgian Association for Cancer Research Annual Meeting 2012.

Peixoto, P., Castronovo, V., Matheus, N., Polese, C., Peulen, O., Gonzalez, A., Boxus, M., Verdin, E., Thiry, M., Dequiedt, F., & Mottet, D. (2012). HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells. Cell Death and Differentiation. doi:10.1038/cdd.2012.3
Peer Reviewed verified by ORBi

Peixoto, P., Castronovo, V., Matheus, N., Polese, C., Peulen, O., Gonzalez, A., Boxus, M., Verdin, E., Thiry, M., Dequiedt, F., & Mottet, D. (2012). Implication of HDAC-5 in heterochromatin replication [Poster presentation]. GIGA-DAY.

Nhili, R., Peixoto, P., Depauw, S., Flajollet, S., Dezitter, X., Munde, M. M., Ismail, M., Kumar, A., Farahat, A., Stephens, C., Duterque-Coquillaud, M., Wilson, D., Boykin, D., & David-Cordonnier, M. H. (2012). Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines. Nucleic Acids Research. doi:10.1093/nar/gks971
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Peixoto, P., Castronovo, V., Matheus, N., Polese, C., Peulen, O., Gonzalez, A., Boxus, M., Verdin, E., Thiry, M., Dequiedt, F., & Mottet, D. (2012). HDAC5 depletion modulates heterochromatin plasticity and triggers programmed cell death of human cancer cells [Poster presentation]. GIGA-DAY.

Turtoi, A., Mottet, D., Matheus, N., Dumont, B., Peixoto, P., Hennequière, V., Deroanne, C., Colige, A., De Pauw, E., Bellahcene, A., & Castronovo, V. (2012). The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells. Angiogenesis. doi:10.1007/s10456-012-9279-8
Peer Reviewed verified by ORBi

Peixoto, P., Pirotte, S., Matheus, N., Castronovo, V., & Mottet, D. (05 February 2011). Histone deacetylase 5 is a regulator of S phase progression [Poster presentation]. Belgian Association for Cancer Research Annual Meeting, Liège, Belgium.

Rebucci, M., Peixoto, P., Dewitte, A., Wattez, N., De Nuncques, M.-A., Rezvoy, N., Vautravers-Dewas, C., Buisine, M.-P., Guerin, E., Peyrat, J.-P., Lartigau, E., & Lansiaux, A. (2011). Mechanisms underlying resistance to cetuximab in the HNSCC cell line: role of AKT inhibition in bypassing this resistance. International Journal of Oncology, 38 (1), 189-200. doi:10.3892/ijo-00000838
Peer Reviewed verified by ORBi

Racane, L., Tralic-Kulenovic, V., Kraljevic Pavelic, S., Ratkaj, I., Peixoto, P., Nhili, R., Depauw, S., Hildebrand, M.-P., David-Cordonnier, M. H., Pavelic, K., & Karminski-Zamola, G. (2010). Novel diamidino-substituted derivatives of phenyl benzothiazolyl and dibenzothiazolyl furans and thiophenes: synthesis, antiproliferative and DNA binding properties. Journal of Medicinal Chemistry, 53 (6), 2418-32. doi:10.1021/jm901441b
Peer Reviewed verified by ORBi

Peixoto, P., Bailly, C., & David-Cordonnier, M. H. (2010). Topoisomerase I-mediated DNA relaxation as a tool to study intercalation of small molecules into supercoiled DNA. In Drug-DNA Interaction Protocols (pp. 235-56). United States: Springer. doi:10.1007/978-1-60327-418-0_15
Peer reviewed

Peixoto, P., Zeghida, W., Carrez, D., Wu, T.-D., Wattez, N., Croisy, A., Demeunynck, M., Guerquin-Kern, J.-L., & Lansiaux, A. (2009). Unusual cellular uptake of cytotoxic 4-hydroxymethyl-3-aminoacridine. European Journal of Medicinal Chemistry, 44 (11), 4758-63. doi:10.1016/j.ejmech.2009.06.034
Peer Reviewed verified by ORBi

Peixoto, P., Depauw, S., Hildebrand, M. P., Boykin, D., Wilson, D., & David-Cordonnier, M. H. (22 October 2008). Sequence-Selective inhibition of the DNA binding potencies of Pit-1 and Brn-3 transcription factors by phenyl-furan-benzimidazole DNA ligands [Poster presentation]. EORTC-NCI-AACR-International Conference on Molecular Targets ans cancer Therapeutics, Geneve, Switzerland.

Peixoto, P., Wilson, D., boykin, Bailly, C., & David-Cordonnier, M. H. (01 February 2008). Specific DNA sequence interaction by new phenyl-furane-benzimidazole derivatives: modulation of the DNA binding activity of transcription factors [Poster presentation]. Pharmacology and Molecular Mechanisms (PAMM) meeting, Palerme, Italy.

Marminon, C., Anizon, F., Moreau, P., Pfeiffer, B., Pierre, A., Golsteyn, R. M., Peixoto, P., Hildebrand, M.-P., David-Cordonnier, M. H., Lozach, O., Meijer, L., & Prudhomme, M. (2008). Rebeccamycin derivatives as dual DNA-damaging agents and potent checkpoint kinase 1 inhibitors. Molecular Pharmacology, 74 (6), 1620-9. doi:10.1124/mol.108.049346
Peer Reviewed verified by ORBi

Peixoto, P., Liu, Y., Depauw, S., Hildebrand, M.-P., Boykin, D. W., Bailly, C., Wilson, W. D., & David-Cordonnier, M. H. (2008). Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication. Nucleic Acids Research, 36 (10), 3341-53. doi:10.1093/nar/gkn208
Peer Reviewed verified by ORBi

Peixoto, P., Lansiaux, L., Wilson, D., Boykin, D., Bailly, C., & David-Cordonnier, M. H. (01 March 2007). Specific DNA sequence interaction by new phenyl-furane-benzimidazole derivatives: modulation of the DNA binding activity of transcription factors [Poster presentation]. Pharmacology and Molecular Mechanisms (PAMM) meeting, Berlin, Germany.

Tanious, F. A., Laine, W., Peixoto, P., Bailly, C., Goodwin, K. D., Lewis, M. A., Long, E. C., Georgiadis, M. M., Tidwell, R. R., & Wilson, W. D. (2007). Unusually strong binding to the DNA minor groove by a highly twisted benzimidazole diphenylether: induced fit and bound water. Biochemistry, 46 (23), 6944-56. doi:10.1021/bi700288g
Peer Reviewed verified by ORBi

Munde, M., Ismail, M. A., Arafa, R., Peixoto, P., Collar, C. J., Liu, Y., Hu, L., David-Cordonnier, M. H., Lansiaux, A., Bailly, C., Boykin, D. W., & Wilson, W. D. (2007). Design of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif. Journal of the American Chemical Society, 129 (44), 13732-43. doi:10.1021/ja074560a
Peer Reviewed verified by ORBi

Munde, M., Ismail, M., Peixoto, P., Collar, C., Nanjunda, R., David-Cordonnier, M. H., Lansiaux, A., Bailly, C., Boykin, D., & Wilson, D. (2007). Effect of base mutations in GC rich binding site on recognition by minor groove binding dications [Poster presentation]. Sermacs, Greenville, United States.

Peixoto, P., Hildebrand, M. P., Baldeyrou, B., Dassy, C., Lansiaux, A., Bailly, C., Messaoudi, S., Marminon, C., Prudhomme, M., & David-Cordonnier, M. H. (02 June 2006). DNA interaction properties and topoisomerase I poisoning efficiencies of a new series of aza-indolocarbazole derivatives [Poster presentation]. Journée Franco-Belge de pharmacochimie.

Messaoudi, S., Anizon, F., Peixoto, P., David-Cordonnier, M. H., Golsteyn, R. M., Leonce, S., Pfeiffer, B., & Prudhomme, M. (2006). Synthesis and biological activities of 7-aza rebeccamycin analogues bearing the sugar moiety on the nitrogen of the pyridine ring. Bioorganic and Medicinal Chemistry, 14 (22), 7551-62. doi:10.1016/j.bmc.2006.07.013
Peer Reviewed verified by ORBi

Peixoto, P., & Lansiaux, A. (2006). La saga des inhibiteurs des histone-desacetylases: de la TSA au SAHA. Bulletin du Cancer, 93 (1), 27-36.
Peer Reviewed verified by ORBi

Routier, S., Peixoto, P., Merour, J.-Y., Coudert, G., Dias, N., Bailly, C., Pierre, A., Leonce, S., & Caignard, D.-H. (2005). Synthesis and biological evaluation of novel naphthocarbazoles as potential anticancer agents. Journal of Medicinal Chemistry, 48 (5), 1401-13. doi:10.1021/jm049213f
Peer Reviewed verified by ORBi

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