![]() ![]() | Turtoi, A., Mottet, D., Matheus, N., Dumont, B., Peixoto, P., Hennequière, V., Deroanne, C., Colige, A., De Pauw, E., Bellahcene, A., & Castronovo, V. (2024). Correction: The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells. Angiogenesis, 27 (1), 121 - 122. doi:10.1007/s10456-023-09898-1 ![]() |
![]() ![]() | Viot, J., Abdeljaoued, S., Vienot, A., Seffar, E., Spehner, L., Bouard, A., Asgarov, K., Pallandre, J.-R., Renaude, E., Klajer, E., Molimard, C., Monnien, F., Bibeau, F., Turco, C., Heyd, B., Peixoto, P., Hervouet, E., Loyon, R., Doussot, A., ... Kroemer, M. (April 2023). CD8+ CD226high T cells in liver metastases dictate the prognosis of colorectal cancer patients treated with chemotherapy and radical surgery. Cellular and Molecular Immunology, 20 (4), 365 - 378. doi:10.1038/s41423-023-00978-2 ![]() |
![]() ![]() | Vienot, A., Pallandre, J.-R., Renaude, E., Viot, J., Bouard, A., Spehner, L., Kroemer, M., Abdeljaoued, S., van der Woning, B., de Haard, H., Loyon, R., Hervouet, E., Peixoto, P., & Borg, C. (2022). Chemokine switch regulated by TGF-β1 in cancer-associated fibroblast subsets determines the efficacy of chemo-immunotherapy. Oncoimmunology, 11 (1), 2144669. doi:10.1080/2162402X.2022.2144669 ![]() |
![]() ![]() | Renaude, E., Kroemer, M., Borg, C., Peixoto, P., Hervouet, E., Loyon, R., & Adotévi, O. (2021). Epigenetic Reprogramming of CD4+ Helper T Cells as a Strategy to Improve Anticancer Immunotherapy. Frontiers in Immunology, 12, 669992. doi:10.3389/fimmu.2021.669992 ![]() |
![]() ![]() | Renaude, E., Kroemer, M., Loyon, R., Binda, D., Borg, C., Guittaut, M., Hervouet, E., & Peixoto, P. (29 February 2020). The Fate of Th17 Cells is Shaped by Epigenetic Modifications and Remodeled by the Tumor Microenvironment. International Journal of Molecular Sciences, 21 (5), 1673. doi:10.3390/ijms21051673 ![]() |
![]() ![]() | Hendrick, E., Peixoto, P., Blomme, A., Polese, C., Matheus, N., Cimino, J., Frère, A., Mouithys-Mickalad, A., Serteyn, D., Bettendorff, L., Elmoualij, B., De Tullio, P., Eppe, G., Dequiedt, F., Castronovo, V., & Mottet, D. (2017). Metabolic inhibitors accentuate the anti-tumoral effect of HDAC5 inhibition. Oncogene. doi:10.1038/onc.2017.103 ![]() |
![]() ![]() | Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Peulen, O., Blomme, A., Turtoi, A., Costanza, B., Smargiasso, N., Baiwir, D., Scheijen, J., Schalkwijk, C., Leenders, J., De Tullio, P., BIANCHI, E., Thiry, M., Uchida, K., Spiegel, D., Cochrane, J., ... Bellahcene, A. (2016). Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP- mediated tumor growth and metastasis. eLife. doi:10.7554/eLife.19375 ![]() |
![]() ![]() | Henry, A., Nokin, M.-J., Leroi, N., Lallemand, F., Lambert, J., Goffart, N., RONCARATI, P., BIANCHI, E., Peixoto, P., Blomme, A., Turtoi, A., Peulen, O., Habraken, Y., Scholtes, F., Martinive, P., Delvenne, P., Rogister, B., Castronovo, V., & Bellahcene, A. (2016). New role of osteopontin in DNA repair and impact on human glioblastoma radiosensitivity. Oncotarget. doi:10.18632/oncotarget.11483 ![]() |
![]() ![]() | Henry, A., Nokin, M.-J., Leroi, N., LALLEMAND, F., Lambert, J., Goffart, N., Peixoto, P., Blomme, A., BIANCHI, E., Habraken, Y., RONCARATI, P., Peulen, O., SCHOLTES, F., MARTINIVE, P., Rogister, B., Delvenne, P., Turtoi, A., Castronovo, V., & Bellahcene, A. (22 March 2016). Osteopontin predicts radiotherapy response of glioblastoma patients : new role in DNA damage repair [Paper presentation]. 3rd Symposium on small animal precision image-guided radiotherapy, Gand, Belgium. |
![]() ![]() | Fahmy, K., Gonzalez, A., Arafa, M., Peixoto, P., Bellahcene, A., Turtoi, A., Delvenne, P., Thiry, M., Castronovo, V., & Peulen, O. (2016). Myoferlin plays a key role in VEGFA secretion and impacts tumor-associated angiogenesis in human pancreas cancer. International Journal of Cancer, 138, 652-663. doi:10.1002/ijc.29820 ![]() |
![]() ![]() | Peixoto, P.* , Blomme, A.* , Costanza, B.* , Ronca, R., Rezzola, S., Palacios, A., SCHOYSMAN, L., Boutry, S., Goffart, N., Peulen, O., Maris, P., Di Valentin, E., Hennequière, V., BIANCHI, E., Henry, A., Meunier, P., Rogister, B., MULLER, R., Delvenne, P., ... Turtoi, A. (2016). HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and PTEN: new opportunities for selected targeted therapies. Oncogene. doi:10.1038/onc.2015.506 ![]() * These authors have contributed equally to this work. |
Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Eppe, G., Castronovo, V., & Mottet, D. (03 December 2015). Compensatory Metabolism Promotes Cancer Cell Adaptation to HDAC5 Silencing [Poster presentation]. Séminaires des chercheurs Télévie 2016, Gembloux, Belgium. |
Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Peulen, O., Blomme, A., Turtoi, A., Costanza, B., Smargiasso, N., Baiwir, D., Leenders, J., De Tullio, P., BIANCHI, E., Thiry, M., Uchida, K., Spiegel, D., Cochrane, J., Hutton, C., De Pauw, E., ... Bellahcene, A. (29 September 2015). Methylglyoxal, a glycolysis side-product, induces Hsp90 post-translational glycation and YAP-mediated breast tumor growth and metastasis [Poster presentation]. Cancer and Metabolism Conference, Cambridge, United Kingdom. |
![]() ![]() | Durieux, F., Peixoto, P., Chiavarina, B., Nokin, M.-J., Karoyan, P., Castronovo, V., & Bellahcene, A. (28 September 2015). Characterization of new carbonyl scavenger molecules and their subsequent use for cancer therapy [Poster presentation]. Cancer and Metabolism Abcam 2015 Conference, Cambridge, United Kingdom. |
![]() ![]() | Henry, A., Bellahcene, A., Castronovo, V., Peixoto, P., Goffart, N., Lallemand, F., Leroi, N., Peulen, O., MARTINIVE, P., Habraken, Y., Turtoi, A., Rogister, B., & Blomme, A. (Other coll.). (10 September 2015). Osteopontin as a new target in glioblastoma progression and resistance to radiotherapy [Paper presentation]. II International Symposium on clinical and basic investigation in glioblastoma, Toledo, Spain. |
Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Peulen, O., Blomme, A., Smargiasso, N., De Tullio, P., BIANCHI, E., Baiwir, D., Thiry, M., Turtoi, A., De Pauw, E., DELVENNE, P., Castronovo, V., & Bellahcene, A. (09 September 2015). Methylglyoxal, a glycolysis side-product, induces Hsp90 post-translational glycation and YAP-mediated breast tumor growth and metastasis [Poster presentation]. Metabolism in Cancer and Stromal Cells, Leuven, Belgium. |
Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (11 February 2015). HDAC5 Depletion in Cancer Cells Induces an Oxidative Stress and Leads to a Metabolic Reprogramming toward Glucose and Glutamine Metabolism [Poster presentation]. Seminaires des chercheurs Télévie 2015, Bruxelles, Belgium. |
Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (31 January 2015). HDAC5 Depletion in Cancer Cells Induces an Oxidative Stress and Leads to a Metabolic Reprogramming toward Glucose and Glutamine Metabolism [Poster presentation]. ABEC TUmor Metabolism and Mitochondria, Bruxelles, Belgium. |
Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (27 January 2015). HDAC5 Depletion in Cancer Cells Induces an Oxidative Stress and Leads to a Metabolic Reprogramming toward Glucose and Glutamine Metabolism [Poster presentation]. Giga Cancer Day 2015 Current Advances in Medical Genetics and Genomics, Liège, Belgium. |
![]() ![]() | Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Smargiasso, N., Baiwir, D., De Pauw, E., De Tullio, P., Thiry, M., Peulen, O., Turtoi, A., Castronovo, V., & Bellahcene, A. (27 January 2015). Accumulation of methylglyoxal, a glycolysis by-product modulates YAP1 transcription co-factor localization and activity in human breast cancer cells through HSP90 modification [Poster presentation]. GIGA-DAY: Current advances in medical genetics and genomics, Liège, Belgium. |
![]() ![]() | Frère, A., Kawalec, M., Tempelaar, S., Peixoto, P., Hendrick, E., Peulen, O., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (2015). Impact of the Structure of Biocompatible Aliphatic Polycarbonates on siRNA Transfection Ability. Biomacromolecules. doi:10.1021/bm501676p ![]() |
Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (30 September 2014). HDAC5 Depletion in Cancer Cells Induces an Oxidative Stress and Leads to a Metabolic Reprogramming toward Glucose and Glutamine Metabolism [Paper presentation]. Annual Mini symposium 2014, Liège, Belgium. |
Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (25 September 2014). HDAC5 Depletion in Cancer Cells Induces an Oxidative Stress and Leads to a Metabolic Reprogramming toward Glucose and Glutamine Metabolism [Poster presentation]. Metabolism and Cancer Nice, Nice, France. |
![]() ![]() | Frère, A., Tempelaar, S., Peixoto, P., Peulen, O., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (28 August 2014). Polyplex based on polycarbonate polymesr for an efficient delivery of an anti-angiogenic siRNA [Paper presentation]. Translational Nanomedicine, Angers, France. |
![]() ![]() | Chiavarina, B.* , Nokin, M.-J.* , Durieux, F., BIANCHI, E., Turtoi, A., Peulen, O., Peixoto, P., Irigaray, P., Uchida, K., Belpomme, D., Delvenne, P., Castronovo, V., & Bellahcene, A. (2014). Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypes. Oncotarget. doi:10.18632/oncotarget.2121 ![]() * These authors have contributed equally to this work. |
Frère, A., Kawalec, M., Tempelaar, S., Peixoto, P., Peulen, O., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (26 May 2014). Impact of the Structure of Biocompatible Aliphatic Polycarbonate on siRNA Transfection Ability [Poster presentation]. Advanced Functional Polymers for Medicine AFPM) 2014, Liège, Belgium. |
Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (19 May 2014). Glucose-dependent metabolic reprogramming in HDAC5-depleted cancer cells [Poster presentation]. Giga Cancer Day 2014 THE LYMPHATIC SYSTEM : THE BED AND BENCH POINT OF VIEWS, Liège, Belgium. |
Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (25 April 2014). Glucose-dependent metabolic reprogramming in HDAC5-depleted cancer cells [Poster presentation]. Reactive Oxygen Species in Cell Metabolism 11th Meeting of the FRS-FNRS contact group on oxidative stress and anti-oxidants 210th Meeting of the Belgian Society of Biochemistry and Molecular Biology, Belgium. |
Frère, A., Peixoto, P., Kawalec, M., Evrard, B., Mespouille, L., Mottet, D., & Piel, G. (April 2014). Polyplexes Targeting Angiogenesis in Cancer [Poster presentation]. 9th World Meeting on Pharmaceutics, Biopharmaceuticsand Pharmaceutical Technology, Lisbon, Portugal. |
Hendrick, E., Peixoto, P., Polese, C., Matheus, N., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Castronovo, V., & Mottet, D. (01 February 2014). Complex I Mitochondrial Dysfunction in HDAC5-depleted Cancer Cells Induces Glucose-dependent Metabolic Reprogramming [Poster presentation]. Association Belge pour l'étude du cancer A.B.E.C 2014, Anvers, Belgium. |
Hendrick, E., Peixoto, P., Matheus, N., Polese, C., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Sonveaux, P., Castronovo, V., & Mottet, D. (27 January 2014). Complex I Mitochondrial Dysfunction in HDAC5-depleted Cancer Cells Induces Glucose-dependent Metabolic Reprogramming [Poster presentation]. Giga Day 2014, Liège, Belgium. |
![]() ![]() | Matheus, N., Hansen, S., Rozet, E., Peixoto, P., Maquoi, E., LAMBERT, V., Noël, A., Frederich, M., Mottet, D., & De Tullio, P. (January 2014). An Easy, Convenient Cell and Tissue Extraction Protocol for Nuclear Magnetic Resonance Metabolomics. Phytochemical Analysis, 25, 342-349. doi:10.1002/pca.2498 ![]() |
![]() ![]() | Frère, A., Kawalec, M., Tempelaar, S., Peixoto, P., Peulen, O., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (2014). Polyplex Based On Polycarbonate Polymers For An Efficient Delivery Of An Anti-Angiogenic siRNA [Poster presentation]. 3rd NanoFar Autumn School, Brussels, Belgium. |
Hendrick, E., Matheus, N., Peixoto, P., Polese, C., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., Elmoualij, B., De Tullio, P., Castronovo, V., & Mottet, D. (05 December 2013). HDAC5 depletion Decreases NDUFB5 Subunit of Mitochondrial Complex- I leading to Glucose-dependent Metabolic Reprogrammation [Poster presentation]. Séminaire des chercheurs Télévie 2014, Bruxelles, Belgium. |
Frère, A., Kawalec, M., Peixoto, P., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (December 2013). The intracellular fate of polycarbonate Polyplexes modulates the efficacy of siRNA [Poster presentation]. 28th GTRV annual meeting, Orleans, France. |
![]() ![]() | Frère, A., Peixoto, P., Mottet, D., & Piel, G. (17 October 2013). Polyplexes based on polycarbonate polymers and siRNA against HDAC7 for a targeted anti-angiogenic therapy [Paper presentation]. 17th forum of Pharmaceutical Sciences, Spa, Belgium. |
Hendrick, E., Matheus, N., Peixoto, P., Polese, C., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Castronovo, V., & Mottet, D. (13 September 2013). Complexe I mitochondrial dysfunction in HDAC5 depleted cancer cells induces glucose-dependent metabolic reprogrammation [Poster presentation]. Annual Mini symposium 2013, Bruxelles, Belgium. |
![]() ![]() | Peulen, O.* , Gonzalez, A.* , Peixoto, P., Turtoi, A., Mottet, D., Delvenne, P., & Castronovo, V. (11 September 2013). The Anti-Tumor Effect of HDAC Inhibition in a Human Pancreas Cancer Model Is Significantly Improved by the Simultaneous Inhibition of Cyclooxygenase 2. PLoS ONE, 8 (9), 75102. doi:10.1371/journal.pone.0075102 ![]() * These authors have contributed equally to this work. |
Gonzalez, A., Peixoto, P., Turtoi, A., Mottet, D., Delvenne, P., Castronovo, V., & Peulen, O. (11 July 2013). Concomitant inhibition of class I HDAC and COX-2 exerts a antitumor effect in a human pancreatic cancer model [Poster presentation]. WIN2013 Symposium: "Personalized Cancer Therapy: from innovation to implemantation". |
Hendrick, E., Matheus, N., Peixoto, P., Polese, C., Blomme, A., Mouithys-Mickalad, A., Serteyn, D., De Tullio, P., Elmoualij, B., Castronovo, V., & Mottet, D. (17 May 2013). Mitochondrial dysfunction in HDAC5-depleted cancer cells induces glucose-dependent metabolic adaptation [Poster presentation]. GIGA-Cancer Day 2013, Liège, Belgium. |
Hendrick, E., Matheus, N., Peixoto, P., Polese, C., Mouithys-Mickalad, A., Serteyn, D., Michiels, C., Castronovo, V., & Mottet, D. (02 February 2013). JNK/ROS signaling pathway is responsible for induction of autophagy in HDAC5 depleted cancer cells [Poster presentation]. Association Belge pour l'étude du cancer A.B.E.C 2013, Gand, Belgium. |
Hendrick, E., Matheus, N., Peixoto, P., Polese, C., Mouithys-Mickalad, A., Serteyn, D., Castronovo, V., & Mottet, D. (29 January 2013). JNK/ROS Signaling Pathway Is Responsible for Induction of Autophagy in HDAC5 depleted Cancer Cells [Paper presentation]. Journée Scientifique des doctorants en sciences Biomédicales et Pharmaceutiques, Mons, Belgium. |
Hendrick, E., Matheus, N., Peixoto, P., Polese, C., Thiry, M., Mouithys-Mickalad, A., Serteyn, D., & Castronovo, V. (28 January 2013). JNK/ROS signaling pathway is responsible for induction of autophagy in HDAC5 depleted cancer cells [Poster presentation]. Giga Day 2013, Liège, Belgium. |
![]() ![]() | Turtoi, A.* , Blomme, A.* , Bellahcene, A., Gilles, C., Hennequière, V., Peixoto, P., BIANCHI, E., Noël, A., De Pauw, E., LIFRANGE, E., Delvenne, P., & Castronovo, V. (2013). Myoferlin is a key regulator of EGFR activity in breast cancer. Cancer Research, 73, 5438-5448. doi:10.1158/0008-5472.CAN-13-1142 ![]() * These authors have contributed equally to this work. |
![]() ![]() | Martin, M., Geudens, I., Bruyr, J., Potente, M., Bleuart, A., Lebrun, M., Simonis, N., Deroanne, C., Twizere, J.-C., Soubeyran, P., Peixoto, P., Mottet, D., Janssens, V., Hofmann, W.-K., Claes, F., Carmeliet, P., Kettmann, R., Gerhardt, H., & Dequiedt, F. (2013). PP2A regulatory subunit Balpha controls endothelial contractility and vessel lumen integrity via regulation of HDAC7. EMBO Journal. doi:10.1038/emboj.2013.187 ![]() |
![]() ![]() | Bournine, L., Bensalem, S., Peixoto, P., Gonzalez, A., Maiza-Benabdesselam, F., Bedjou, F., Wauters, J.-N., Tits, M., Frederich, M., Castronovo, V., & Bellahcene, A. (2013). Revealing the anti-tumoral effect of Algerian Glaucium flavum roots against human cancer cells. Phytomedicine, 20 (13), 1211-1218. doi:10.1016/j.phymed.2013.06.007 ![]() |
Hendrick, E., Peixoto, P., Matheus, N., Polese, C., Castronovo, V., & Mottet, D. (10 December 2012). Role of HDAC5 depletion induced autophagy on cancer cell death [Poster presentation]. Séminaires des chercheurs Télévie 2013, Liège, Belgium. |
![]() ![]() | Frère, A., Kawalec, M., Collard, L., Matheus, N., Peixoto, P., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (22 October 2012). Characterization and transfection experiments of polyplexes targeting HDAC7 [Poster presentation]. NanoFar Autumn School, Angers, France. |
Castronovo, V., Matheus, N., Dumont, B., Peixoto, P., Hennequière, V., Deroanne, C., Colige, A., De Pauw, E., Bellahcene, A., Mottet, D., & Turtoi, A. (21 April 2012). The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells [Paper presentation]. Experimental Biology 2012, SAN DIEGO, United States. |
Peixoto, P., Matheus, N., Polese, C., gonzalez, A., Castronovo, V., & Mottet, D. (04 February 2012). HDAC5 is required for maintenance of pericentric heterochromatin and controls cell cycle progression of human cancer cells [Poster presentation]. Belgian Association for Cancer Research Annual Meeting 2012. |
![]() ![]() | Peixoto, P., Castronovo, V., Matheus, N., Polese, C., Peulen, O., Gonzalez, A., Boxus, M., Verdin, E., Thiry, M., Dequiedt, F., & Mottet, D. (2012). HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells. Cell Death and Differentiation. doi:10.1038/cdd.2012.3 ![]() |
![]() ![]() | Nhili, R., Peixoto, P., Depauw, S., Flajollet, S., Dezitter, X., Munde, M. M., Ismail, M., Kumar, A., Farahat, A., Stephens, C., Duterque-Coquillaud, M., Wilson, D., Boykin, D., & David-Cordonnier, M. H. (2012). Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines. Nucleic Acids Research. doi:10.1093/nar/gks971 ![]() |
![]() ![]() | Peixoto, P., Castronovo, V., Matheus, N., Polese, C., Peulen, O., Gonzalez, A., Boxus, M., Verdin, E., Thiry, M., Dequiedt, F., & Mottet, D. (2012). Implication of HDAC-5 in heterochromatin replication [Poster presentation]. GIGA-DAY. |
![]() ![]() | Peixoto, P., Castronovo, V., Matheus, N., Polese, C., Peulen, O., Gonzalez, A., Boxus, M., Verdin, E., Thiry, M., Dequiedt, F., & Mottet, D. (2012). HDAC5 depletion modulates heterochromatin plasticity and triggers programmed cell death of human cancer cells [Poster presentation]. GIGA-DAY. |
![]() ![]() | Turtoi, A., Mottet, D., Matheus, N., Dumont, B., Peixoto, P., Hennequière, V., Deroanne, C., Colige, A., De Pauw, E., Bellahcene, A., & Castronovo, V. (2012). The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells. Angiogenesis. doi:10.1007/s10456-012-9279-8 ![]() |
Peixoto, P., Pirotte, S., Matheus, N., Castronovo, V., & Mottet, D. (05 February 2011). Histone deacetylase 5 is a regulator of S phase progression [Poster presentation]. Belgian Association for Cancer Research Annual Meeting, Liège, Belgium. |
![]() ![]() | Rebucci, M., Peixoto, P., Dewitte, A., Wattez, N., De Nuncques, M.-A., Rezvoy, N., Vautravers-Dewas, C., Buisine, M.-P., Guerin, E., Peyrat, J.-P., Lartigau, E., & Lansiaux, A. (2011). Mechanisms underlying resistance to cetuximab in the HNSCC cell line: role of AKT inhibition in bypassing this resistance. International Journal of Oncology, 38 (1), 189-200. doi:10.3892/ijo-00000838 ![]() |
![]() ![]() | Racane, L., Tralic-Kulenovic, V., Kraljevic Pavelic, S., Ratkaj, I., Peixoto, P., Nhili, R., Depauw, S., Hildebrand, M.-P., David-Cordonnier, M. H., Pavelic, K., & Karminski-Zamola, G. (2010). Novel diamidino-substituted derivatives of phenyl benzothiazolyl and dibenzothiazolyl furans and thiophenes: synthesis, antiproliferative and DNA binding properties. Journal of Medicinal Chemistry, 53 (6), 2418-32. doi:10.1021/jm901441b ![]() |
![]() ![]() | Peixoto, P., Bailly, C., & David-Cordonnier, M. H. (2010). Topoisomerase I-mediated DNA relaxation as a tool to study intercalation of small molecules into supercoiled DNA. In Drug-DNA Interaction Protocols (pp. 235-56). United States: Springer. doi:10.1007/978-1-60327-418-0_15 ![]() |
![]() ![]() | Peixoto, P., Zeghida, W., Carrez, D., Wu, T.-D., Wattez, N., Croisy, A., Demeunynck, M., Guerquin-Kern, J.-L., & Lansiaux, A. (2009). Unusual cellular uptake of cytotoxic 4-hydroxymethyl-3-aminoacridine. European Journal of Medicinal Chemistry, 44 (11), 4758-63. doi:10.1016/j.ejmech.2009.06.034 ![]() |
Peixoto, P., Depauw, S., Hildebrand, M. P., Boykin, D., Wilson, D., & David-Cordonnier, M. H. (22 October 2008). Sequence-Selective inhibition of the DNA binding potencies of Pit-1 and Brn-3 transcription factors by phenyl-furan-benzimidazole DNA ligands [Poster presentation]. EORTC-NCI-AACR-International Conference on Molecular Targets ans cancer Therapeutics, Geneve, Switzerland. |
Peixoto, P., Wilson, D., boykin, Bailly, C., & David-Cordonnier, M. H. (01 February 2008). Specific DNA sequence interaction by new phenyl-furane-benzimidazole derivatives: modulation of the DNA binding activity of transcription factors [Poster presentation]. Pharmacology and Molecular Mechanisms (PAMM) meeting, Palerme, Italy. |
![]() ![]() | Marminon, C., Anizon, F., Moreau, P., Pfeiffer, B., Pierre, A., Golsteyn, R. M., Peixoto, P., Hildebrand, M.-P., David-Cordonnier, M. H., Lozach, O., Meijer, L., & Prudhomme, M. (2008). Rebeccamycin derivatives as dual DNA-damaging agents and potent checkpoint kinase 1 inhibitors. Molecular Pharmacology, 74 (6), 1620-9. doi:10.1124/mol.108.049346 ![]() |
![]() ![]() | Peixoto, P., Liu, Y., Depauw, S., Hildebrand, M.-P., Boykin, D. W., Bailly, C., Wilson, W. D., & David-Cordonnier, M. H. (2008). Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication. Nucleic Acids Research, 36 (10), 3341-53. doi:10.1093/nar/gkn208 ![]() |
Peixoto, P., Lansiaux, L., Wilson, D., Boykin, D., Bailly, C., & David-Cordonnier, M. H. (01 March 2007). Specific DNA sequence interaction by new phenyl-furane-benzimidazole derivatives: modulation of the DNA binding activity of transcription factors [Poster presentation]. Pharmacology and Molecular Mechanisms (PAMM) meeting, Berlin, Germany. |
![]() ![]() | Tanious, F. A., Laine, W., Peixoto, P., Bailly, C., Goodwin, K. D., Lewis, M. A., Long, E. C., Georgiadis, M. M., Tidwell, R. R., & Wilson, W. D. (2007). Unusually strong binding to the DNA minor groove by a highly twisted benzimidazole diphenylether: induced fit and bound water. Biochemistry, 46 (23), 6944-56. doi:10.1021/bi700288g ![]() |
![]() ![]() | Munde, M., Ismail, M. A., Arafa, R., Peixoto, P., Collar, C. J., Liu, Y., Hu, L., David-Cordonnier, M. H., Lansiaux, A., Bailly, C., Boykin, D. W., & Wilson, W. D. (2007). Design of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif. Journal of the American Chemical Society, 129 (44), 13732-43. doi:10.1021/ja074560a ![]() |
Munde, M., Ismail, M., Peixoto, P., Collar, C., Nanjunda, R., David-Cordonnier, M. H., Lansiaux, A., Bailly, C., Boykin, D., & Wilson, D. (2007). Effect of base mutations in GC rich binding site on recognition by minor groove binding dications [Poster presentation]. Sermacs, Greenville, United States. |
Peixoto, P., Hildebrand, M. P., Baldeyrou, B., Dassy, C., Lansiaux, A., Bailly, C., Messaoudi, S., Marminon, C., Prudhomme, M., & David-Cordonnier, M. H. (02 June 2006). DNA interaction properties and topoisomerase I poisoning efficiencies of a new series of aza-indolocarbazole derivatives [Poster presentation]. Journée Franco-Belge de pharmacochimie. |
![]() ![]() | Peixoto, P., & Lansiaux, A. (2006). La saga des inhibiteurs des histone-desacetylases: de la TSA au SAHA. Bulletin du Cancer, 93 (1), 27-36. ![]() |
![]() ![]() | Messaoudi, S., Anizon, F., Peixoto, P., David-Cordonnier, M. H., Golsteyn, R. M., Leonce, S., Pfeiffer, B., & Prudhomme, M. (2006). Synthesis and biological activities of 7-aza rebeccamycin analogues bearing the sugar moiety on the nitrogen of the pyridine ring. Bioorganic and Medicinal Chemistry, 14 (22), 7551-62. doi:10.1016/j.bmc.2006.07.013 ![]() |
![]() ![]() | Routier, S., Peixoto, P., Merour, J.-Y., Coudert, G., Dias, N., Bailly, C., Pierre, A., Leonce, S., & Caignard, D.-H. (2005). Synthesis and biological evaluation of novel naphthocarbazoles as potential anticancer agents. Journal of Medicinal Chemistry, 48 (5), 1401-13. doi:10.1021/jm049213f ![]() |