Profil

Darcis Gilles

Département de médecine interne > Service des maladies infectieuses - médecine interne

See author's contact details
Main Research Fields
Immunology & infectious disease
Genetics & genetic processes
Microbiology
General & internal medicine
Public health, health care sciences & services
Main Keywords
HIV; Humans; COVID-19; Human immunodeficiency virus 1; Adult;
Main Unit & Research Centers
GIGA-I3 - Giga-Infection, Immunity and Inflammation - ULiège
Main Co-authors
Moutschen, Michel 
Maes, Nathalie 
Meuris, Christelle 
Vaira, Dolorès 
Leonard, Philippe 

Publications (total 69)

The most downloaded
145 downloads
Cruz, R., Almeida, S. D.-D., Heredia, M. L., Quintela, I., Ceballos, F. C., Pita, G., Lorenzo-Salazar, J. M., González-Montelongo, R., Gago-Domínguez, M., Porras, M. S., Castaño, J. A. T., Nevado, J., Aguado, J. M., Aguilar, C., Aguilera-Albesa, S., Almadana, V., Almoguera, B., Alvarez, N., Andreu-Bernabeu, Á., & Carracedo, Á. (2022). Novel genes and sex differences in COVID-19 severity. Human Molecular Genetics. doi:10.1093/hmg/ddac132 https://hdl.handle.net/2268/292383
The most cited
222 citations (OCI)
The COVID-19 Host Genetics Initiative, Gazon, H., JUSZCZAK, D., FADEUR, M., CAMBY, S., MEURIS, C., THYS, M., JACQUES, J., HENKET, M., BEGUIN, Y., Rahmouni, S., Lebrun, M., MOUTSCHEN, M., Misset, B., DARCIS, G., GUIOT, J., AZARZAR, S., DELLOT, P., GOFFLOT, S., & HUYNEN, P. (Other coll.). (2021). Mapping the human genetic architecture of COVID-19. Nature, 600, 472-477. doi:10.1038/s41586-021-03767-x https://hdl.handle.net/2268/260539

Paridans, M., Monseur, J., Donneau, A.-F., Gillain, N., Husson, E., Leclercq, D., Meuris, C., Darcis, G., Moutschen, M., Saegerman, C., Gillet, L., Bureau, F., Guillaume, M., & Pétré, B. (2022). The Dynamic Relationship between the Intention and Final Decision for the COVID-19 Booster: A Study among Students and Staff at the University of Liège, Belgium. Vaccines. doi:10.3390/vaccines10091485
Peer Reviewed verified by ORBi

El Moussaoui, M., Desmecht, S., Tashkeev, A., Lambert, N., Maes, N., Braghini, J., MARECHAL, N., Quintana, C., BRIQUET, K., Gofflot, S., TOUSSAINT, F., Hayette, M.-P., Vermeersch, P., Lutteri, L., Grégoire, C., Beguin, Y., Rahmouni, S., Moutschen, M., Desmecht, D., & Darcis, G. (2022). Reduced T-cell response following a third dose of SARS-CoV-2 vaccine in infection-naïve people living with HIV. Journal of Infection. doi:10.1016/j.jinf.2022.09.006
Peer Reviewed verified by ORBi

Pathak, G. A., Karjalainen, J., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Andrews, S. J., Kanai, M., Cordioli, M., Polimanti, R., Harerimana, N., Pirinen, M., Liao, R. G., Chwialkowska, K., Trankiem, A., Balaconis, M. K., Nguyen, H., Solomonson, M., Veerapen, K., & Baillie, J. K. (2022). A first update on mapping the human genetic architecture of COVID-19. Nature. doi:10.1038/s41586-022-04826-7
Peer Reviewed verified by ORBi

Cruz, R., Almeida, S. D.-D., Heredia, M. L., Quintela, I., Ceballos, F. C., Pita, G., Lorenzo-Salazar, J. M., González-Montelongo, R., Gago-Domínguez, M., Porras, M. S., Castaño, J. A. T., Nevado, J., Aguado, J. M., Aguilar, C., Aguilera-Albesa, S., Almadana, V., Almoguera, B., Alvarez, N., Andreu-Bernabeu, Á., & Carracedo, Á. (2022). Novel genes and sex differences in COVID-19 severity. Human Molecular Genetics. doi:10.1093/hmg/ddac132
Peer Reviewed verified by ORBi

El Moussaoui, M., Maes, N., Hong, S. L., Lambert, N., Gofflot, S., DELLOT, P., Belhadj, Y., Huynen, P., Hayette, M.-P., Meex, C., Bontems, S., Defêche, J., Godderis, L., Molenberghs, G., Meuris, C., Artesi, M., Durkin, K., Rahmouni, S., GREGOIRE, C., & DARCIS, G. (14 June 2022). Evaluation of Screening Program and Phylogenetic Analysis of SARS-CoV-2 Infections among Hospital Healthcare Workers in Liège, Belgium. Viruses, 14 (6), 1302. doi:10.3390/v14061302
Peer Reviewed verified by ORBi

Mayasi, N., Situakibanza, H., Mbula, M., Longokolo, M., Maes, N., Bepouka, B., Ossam, J. O., MOUTSCHEN, M., & DARCIS, G. (11 March 2022). Retention in care and predictors of attrition among HIV-infected patients who started antiretroviral therapy in Kinshasa, DRC, before and after the implementation of the ‘treat-all’ strategy. PLOS Global Public Health, 2 (3), 0000259. doi:10.1371/journal.pgph.0000259
Peer reviewed

Kousathanas, A., Pairo-Castineira, E., Rawlik, K., Stuckey, A., Odhams, C. A., Walker, S., Russell, C. D., Malinauskas, T., Wu, Y., Millar, J., Shen, X., Elliott, K. S., Griffiths, F., Oosthuyzen, W., Morrice, K., Keating, S., Wang, B., Rhodes, D., Klaric, L., & DARCIS, G. (2022). Whole-genome sequencing reveals host factors underlying critical COVID-19. Nature. doi:10.1038/s41586-022-04576-6
Peer Reviewed verified by ORBi

Desmecht, S.* , Tashkeev, A.* , El Moussaoui, M., MARECHAL, N., Perée, H., Tokunaga, Y., Fombellida-Lopez, C., Polese, B., Legrand, C., Wéry, M., Mni, M., Fouillien, N., TOUSSAINT, F., Gillet, L., Bureau, F., LUTTERI, L., HAYETTE, M.-P., MOUTSCHEN, M., MEURIS, C., & DARCIS, G.*. (2022). Kinetics and persistence of the cellular and humoral immune responses to BNT162b2 mRNA vaccine in SARS-CoV-2-naive and -experienced subjects: impact of booster dose and breakthrough infections. Frontiers in Immunology, 13, 863554. doi:10.1101/2022.01.17.22269278
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Donneau, A.-F.* , Guillaume, M.* , BOURS, V., Dandoy, M., DARCIS, G., Desmecht, D., Diep, A. N., Fievez, L., Garigliany, M.-M., Gillain, N., Husson, E., Michel, F., MOUTSCHEN, M., Paridans, M., Pétré, B., Sabatel, C., Saegerman, C., Tytgat, A., Gillet, L.* , & Bureau, F.*. (2022). University population-based prospective cohort study of SARS-CoV- 2 infection and immunity (SARSSURV-ULiège): a study protocol. BMJ Open. doi:10.1136/bmjopen-2021-055721
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

El Moussaoui, M., Lambert, N., MAES, N., Fombellida, K., VAIRA, D., MOUTSCHEN, M., & DARCIS, G. (30 November 2021). Impact of the COVID-19 pandemic situation on HIV care in Liège, Belgium. Poster session presented at BREACH Symposium 2021, Bruxelles, Belgium.

Nakanishi, T., Pigazzini, S., Degenhardt, F., Cordioli, M., Butler-Laporte, G., Maya-Miles, D., Nafría-Jiménez, B., Bouysran, Y., Niemi, M., Palom, A., Ellinghaus, D., Khan, A., Martínez-Bueno, M., Rolker, S., Amitano, S., Tato, L. R., Fava, F., Spinner, C. D., Prati, D., & consortium, C.-H. (October 2021). Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality. Journal of Clinical Investigation, Online ahead of print.. doi:10.1172/JCI152386
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El Moussaoui, M., Lambert, N., MAES, N., Fombellida, K., VAIRA, D., MOUTSCHEN, M., & DARCIS, G. (2021). Impact of the COVID-19 pandemic situation on HIV care in Liège, Belgium. HIV Research & Clinical Practice. doi:10.1080/25787489.2021.1948773
Peer Reviewed verified by ORBi

Ngongo, N. M., Darcis, G., Nanituna, H. S., Mambimbi, M. M., Maes, N., Mashi, M. L., Bepouka Izizag, B., Moutschen, M., & Lepira Bompeka, F. (2021). Longitudinal analysis of sociodemographic, clinical and therapeutic factors of HIV-infected individuals in Kinshasa at antiretroviral therapy initiation during 2006-2017. PLoS ONE, 16 (11), 0259073. doi:10.1371/journal.pone.0259073
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Darcis, G., Bouquegneau, A., Maes, N., Thys, M., Henket, M., Labye, F., Rousseau, A.-F., Canivet, P., Desir, C., Calmes, D., Schils, R., De Worm, S., Léonard, P., Meunier, P., Moutschen, M., Louis, R., & Guiot, J. (2021). Long-term clinical follow-up of patients suffering from moderate-to-severe COVID-19 infection: a monocentric prospective observational cohort study. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 109, 209-216. doi:10.1016/j.ijid.2021.07.016
Peer reviewed

Ngongo, N. M., Nani-Tuma, H. S., Mambimbi, M. M., Mashi, M. L., Izizag, B. B., Ndolumingu, F. K., Maes, N., Moutschen, M., & Darcis, G. (2021). Decrease in late presentation for HIV care in Kinshasa, DRC, 2006-2020. AIDS Research and Therapy, 18 (1), 41. doi:10.1186/s12981-021-00366-8
Peer Reviewed verified by ORBi

Ngongo, N. M., Nani-Tuma, H. S., Mambimbi, M. M., Mashi, M. L., Izizag, B. B., Maes, N., Moutschen, M., & Darcis, G. (2021). Progressive phasing out of baseline CD4+ cell count testing for people living with HIV in Kinshasa, Democratic Republic of the Congo. AIDS (London, England), 35 (5), 841-843. doi:10.1097/QAD.0000000000002802
Peer reviewed

Plum, P.-E., Maes, N., Sauvage, A.-S., Frippiat, F., Meuris, C., Uurlings, F., Lecomte, M., Léonard, P., Paquot, N., Fombellida, K., Vaira, D., Moutschen, M., & Darcis, G. (2021). Impact of switch from tenofovir disoproxil fumarate-based regimens to tenofovir alafenamide-based regimens on lipid profile, weight gain and cardiovascular risk score in people living with HIV. BMC Infectious Diseases, 21 (1), 910. doi:10.1186/s12879-021-06479-9
Peer Reviewed verified by ORBi

Gregoire, E., Pirotte, B. F., Moerman, F., Altdorfer, A., Gaspard, L., Firre, E., Moonen, M., Fraipont, V., ERNST, M., & DARCIS, G. (2021). Incidence and Risk Factors of COVID-19-Associated Pulmonary Aspergillosis in Intensive Care Unit-A Monocentric Retrospective Observational Study. Pathogens (Basel, Switzerland), 10 (11). doi:10.3390/pathogens10111370
Peer reviewed

Meuris, C., Kremer, C., Geerinck, A., Locquet, M., Bruyère, O., Defêche, J., Meex, C., Hayette, M.-P., Duchene, L., Dellot, P., Azarzar, S., Maréchal, N., Sauvage, A.-S., Frippiat, F., Giot, J.-B., Léonard, P., Fombellida, K., Moutschen, M., Durkin, K., & Darcis, G. (2021). Transmission of SARS-CoV-2 After COVID-19 Screening and Mitigation Measures for Primary School Children Attending School in Liège, Belgium. JAMA Network Open, 4 (10), 2128757. doi:10.1001/jamanetworkopen.2021.28757
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Defêche, J., AZARZAR, S., Mesdagh, A., DELLOT, P., Tytgat, A., Bureau, F., Gillet, L., Belhadj, Y., BONTEMS, S., HAYETTE, M.-P., Schils, R., Rahmouni, S., ERNST, M., MOUTSCHEN, M., & DARCIS, G. (2021). In-Depth Longitudinal Comparison of Clinical Specimens to Detect SARS-CoV-2. Pathogens (Basel, Switzerland), 10 (11). doi:10.3390/pathogens10111362
Peer reviewed

BOUQUEGNEAU, A., HUART, J., LUTTERI, L., ERPICUM, P., GROSCH, S., Résimont, G., WIESEN, P., ROUSSEAU, A.-F., BOVY, C., KRZESINSKI, J.-M., THYS, M., LAMBERMONT, B., Misset, B., Pottel, H., DARCIS, G., CAVALIER, E., JOURET, F., & DELANAYE, P. (2021). Survivors of COVID-19 mostly recover from tubular proteinuria and acute kidney injury after hospital discharge. Journal of Nephrology, 34 (4), 967-969. doi:10.1007/s40620-021-01075-1
Peer Reviewed verified by ORBi

The COVID-19 Host Genetics Initiative, Gazon, H., JUSZCZAK, D., FADEUR, M., CAMBY, S., MEURIS, C., THYS, M., JACQUES, J., HENKET, M., BEGUIN, Y., Rahmouni, S., Lebrun, M., MOUTSCHEN, M., Misset, B., DARCIS, G., GUIOT, J., AZARZAR, S., DELLOT, P., GOFFLOT, S., & HUYNEN, P. (Other coll.). (2021). Mapping the human genetic architecture of COVID-19. Nature, 600, 472-477. doi:10.1038/s41586-021-03767-x
Peer Reviewed verified by ORBi

Chaslain, A., Fombellida-Lopez, C., SUSIN, F., VAIRA, D., Moutschen, M., & Darcis, G. (September 2020). Obstacles à la guérison de l'infection par le VIH. Partie 2 : la réplication continue malgré le traitement. Revue Médicale de Liège, 75 (9), 582-587.
Peer reviewed

Fombellida-Lopez, C., Chaslain, A., SUSIN, F., VAIRA, D., Moutschen, M., & DARCIS, G. (September 2020). Obstacles à la guérison de l'infection par le VIH. Partie 1 : les réservoirs latents. Revue Médicale de Liège, 75 (9), 573-577.
Peer reviewed

El Moussaoui, M., Lambert, I., MAES, N., SAUVAGE, A.-S., FRIPPIAT, F., MEURIS, C., UURLINGS, F., LECOMTE, M., LEONARD, P., Fombellida, K., VAIRA, D., Vercheval, C., Moutschen, M., & Darcis, G. (2020). Evolution of Drug Interactions With Antiretroviral Medication in People With HIV. Open Forum Infectious Diseases, 7 (11), 416. doi:10.1093/ofid/ofaa416
Peer Reviewed verified by ORBi

Darcis, G., Kootstra, N. A., Hooibrink, B., van Montfort, T., Maurer, I., Groen, K., Jurriaans, S., Bakker, M., van Lint, C., Berkhout, B., & Pasternak, A. O. (2020). CD32+CD4+ T Cells Are Highly Enriched for HIV DNA and Can Support Transcriptional Latency. Cell Reports, 30 (7), 2284-2296.e3. doi:10.1016/j.celrep.2020.01.071
Peer Reviewed verified by ORBi

Darcis, G., Berkhout, B., & Pasternak, A. O. (2020). Differences in HIV Markers between Infected Individuals Treated with Different ART Regimens: Implications for the Persistence of Viral Reservoirs. Viruses, 12 (5). doi:10.3390/v12050489
Peer Reviewed verified by ORBi

Ait-Ammar, A., Kula, A., DARCIS, G., Verdikt, R., De wit, S., Gautier, V., Mallon, P., Marcello, A., Rohr, O., & Van Lint, C. (2020). Current Status of Latency Reversing Agents Facing the Heterogeneity of HIV-1 Cellular and Tissue Reservoirs. Frontiers in Microbiology. doi:10.3389/fmicb.2019.03060
Peer Reviewed verified by ORBi

Ilbert, C., SABATIELLO, M., KURTH, W., Longrée, L., MOUTSCHEN, M., & DARCIS, G. (2020). Le syndrome de Schnitzler. Revue Médicale de Liège.
Peer reviewed

DARCIS, G., VAIRA, D., & MOUTSCHEN, M. (2020). Impact of coronavirus pandemic and containment measures on HIV diagnosis. Epidemiology and Infection. doi:10.1017/S0950268820001867
Peer reviewed

El Moussaoui, M., Lambert, I., MAES, N., SAUVAGE, A.-S., FRIPPIAT, F., MEURIS, C., UURLINGS, F., LECOMTE, M., LEONARD, P., FOMBELLIDA, K., VAIRA, D., Vercheval, C., MOUTSCHEN, M., & DARCIS, G. (22 November 2019). Evolution of drug interactions with antiretroviral medications in HIV-infected patients. Poster session presented at 8th BREACH SYMPOSIUM, Liège, Belgium.

El Moussaoui, M., Lambert, I., MAES, N., SAUVAGE, A.-S., FRIPPIAT, F., MEURIS, C., UURLINGS, F., LECOMTE, M., LEONARD, P., Fombellida, K., VAIRA, D., Vercheval, C., MOUTSCHEN, M., & DARCIS, G. (08 November 2019). Evolution of drug interactions with antiretroviral medications in HIV-infected patients. Paper presented at 17th European AIDS Conference, Bâle, Switzerland.

Verdikt, R., DARCIS, G., Ait-Ammar, A., & Van Lint, C. (2019). Applications of CRISPR/Cas9 tools in deciphering the mechanisms of HIV-1 persistence. Current Opinion in Virology. doi:10.1016/j.coviro.2019.07.004
Peer Reviewed verified by ORBi

Van Montfort, T., Van der sluis, R., DARCIS, G., Beaty, D., Groen, K., Pasternak, A., Pollakis, G., Vink, M., Westerhout, E., Hamdi, M., Bakker, M., Van Der Putten, B., Jurriaans, S., Prins, J., Jeeninga, R., Thomas, A., Speijer, D., & Berkhout, B. (2019). Dendritic cells potently purge latent HIV-1 beyond TCR-stimulation, activating the PI3K-Akt-mTOR pathway. EBioMedicine. doi:10.1016/j.ebiom.2019.02.014
Peer Reviewed verified by ORBi

Moreno, S., Perno, C., Mallon, P., Berhens, G., Corbeau, P., Routy, J., & DARCIS, G. (2019). Two-drug vs. three-drug combinations for HIV-1: Do we have enough data to make the switch? HIV Medicine. doi:10.1111/hiv.12716
Peer Reviewed verified by ORBi

DARCIS, G., Binda, C., Klaver, B., Herrera-Carrillo, E., Berkhout, B., & Das, A. (2019). The Impact of HIV-1 Genetic Diversity on CRISPR-Cas9 Antiviral Activity and Viral Escape. Viruses. doi:10.3390/v11030255
Peer Reviewed verified by ORBi

DARCIS, G., Berkhout, B., & Pasternak, A. (2019). The Quest for Cellular Markers of HIV Reservoirs: Any Color You Like. Frontiers in Immunology. doi:10.3389/fimmu.2019.02251
Peer Reviewed verified by ORBi

DARCIS, G., MAES, N., Pasternak, A., SAUVAGE, A.-S., FRIPPIAT, F., MEURIS, C., UURLINGS, F., LECOMTE, M., LEONARD, P., El Moussaoui, M., Fombellida, K., VAIRA, D.* , & MOUTSCHEN, M.*. (2019). Detectability of HIV residual Viremia despite therapy is highly associated with treatment with a protease inhibitor-based combination antiretroviral therapy. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.01902-19
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Kula, A., Delacourt, N., Bouchat, S., DARCIS, G., Avettand-Fenoel, V., Verdikt, R., Corazza, F., Necsoi, C., Vanhulle, C., Benmoudou, M., Burny, A., de Wit, S., Rouzioux, C., Rohr, O., & Van Lint, C. (2019). Heterogeneous HIV-1 reactivation patterns of disulfiram and combined disulfiram+romidepsin treatments. Journal of Acquired Immune Deficiency Syndromes. doi:10.1097/QAI.0000000000001958
Peer Reviewed verified by ORBi

Cimpaye, O., Louis, R., Darcis, G., Beaudart, C., & MEURIS, C. (2019). Evaluation de l'application des recommandations du Conseil Supérieur de la Santé relatives à l'isolement respiratoire des malades atteints de la tuberculose pulmonaire au CHU de Liège. Revue Médicale de Liège, 74 (9), 465-470.
Peer reviewed

Pirotte, B., FRIPPIAT, F., DARCIS, G., Rassenfosse, M., Fombellida, K., MAES, N., Moerman, F., & MOUTSCHEN, M. (2019). Etude des motifs d'admission au service des Urgences d'une cohorte de patients. Revue Médicale de Liège.
Peer reviewed

DARCIS, G., Lambert, I., SAUVAGE, A.-S., FRIPPIAT, F., MEURIS, C., UURLINGS, F., LECOMTE, M., LEONARD, P., GIOT, J.-B., fombellida, K., VAIRA, D., & MOUTSCHEN, M. (2018). Factors associated with late presentation for HIV care in a single Belgian reference center: 2006-2017. Scientific Reports. doi:10.1038/s41598-018-26852-0
Peer Reviewed verified by ORBi

DARCIS, G., Das, A. T., & Berkhout, B. (2018). Tackling HIV Persistence: Pharmacological versus CRISPR-Based Shock Strategies. Viruses. doi:10.3390/v10040157
Peer Reviewed verified by ORBi

Khoury, G.* , Darcis, G.* , Lee, M., Bouchat, S., Van Driessche, B., Purcell, D. F.* , & Van Lint, C.*. (2018). The Molecular Biology of HIV Latency. Advances in Experimental Medicine and Biology. doi:10.1007/978-981-13-0484-2_8
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

DARCIS, G., & Berkhout, B. (2018). Human Immunodeficiency Virus Resistance to Dolutegravir: Are We Looking in the Wrong Place? Journal of Infectious Diseases. doi:10.1093/infdis/jiy474
Peer Reviewed verified by ORBi

DARCIS, G. (2018). 2 drug combinations: unanswered questions HIV reservoirs. Paper presented at GILEAD symposium, Berlin, Germany.

DARCIS, G., & Moutschen, M. (2018). Wild-type HIV infection despite PrEP: a lot to learn from a case report. Lancet HIV, 5 (1), 10. doi:10.1016/S2352-3018(17)30212-6
Peer reviewed

DARCIS, G., Van Driessche, B., Bouchat, S., Kirchhoff, F., & Van Lint, C. (2018). Molecular Control of HIV and SIV Latency. Current Topics in Microbiology and Immunology. doi:10.1007/82_2017_74
Peer Reviewed verified by ORBi

DE VOEGHT, A., Martens, H., RENARD, J. D. C., VAIRA, D., Debruche, M., Simonet, J., Geenen, V., MOUTSCHEN, M., & DARCIS, G. (2017). Exploring the link between innate immune activation and thymic function by measuring sCD14 and TRECs in HIV patients living in Belgium. PLoS ONE. doi:10.1371/journal.pone.0185761
Peer Reviewed verified by ORBi

DARCIS, G., Van der Auwera, G., GIOT, J.-B., Hayette, M.-P., Tassin, F., Arrese Estrada, J., Cnops, L., Moutschen, M., de Leval, L., & LEONARD, P. (07 July 2017). Recurrence of visceral and muco-cutaneous leishmaniasis in a patient under immunosuppressive therapy. BMC Infectious Diseases, 17. doi:10.1186/s12879-017-2571-x
Peer Reviewed verified by ORBi

DARCIS, G., Van Driessche, B., & Van Lint, C. (2017). HIV Latency: Should We Shock or Lock? Trends in Immunology, 38 (3), 217-228. doi:10.1016/j.it.2016.12.003
Peer Reviewed verified by ORBi

Gama, L., Abreu, C., Shirk, E., Price, S., Li, M., Laird, G., Pate, K., Wietgrefe, S., O'Connor, S., Pianowski, L., Haase, A., Van Lint, C., Siliciano, R., Clements, J., Queen, S., Bullock, B., Croteau, J., Pianowski, L., Gellerup, D., & Mankowski, J. (2017). Reactivation of simian immunodeficiency virus reservoirs in the brain of virally suppressed macaques. AIDS. doi:10.1097/QAD.0000000000001267
Peer Reviewed verified by ORBi

Gunter, J., Callens, S., De Wit, S., Goffard, J.-C., Moutschen, M., DARCIS, G., MEURIS, C., van den Bulcke, C., Fombellida, K., del Forge, M., Razavi, H., & Wyndham-Thomas, C. (2017). Prevalence of non-infectious comorbidities in the HIV-positive population in Belgium: a multicenter, retrospective study. Acta Clinica Belgica, 1-4. doi:10.1080/17843286.2017.1339965
Peer Reviewed verified by ORBi

DARCIS, G., & Moutschen, M. (2017). The effect of treatment simplification on HIV reservoirs. Lancet HIV, 4 (8), 328-e329. doi:10.1016/S2352-3018(17)30135-2
Peer reviewed

Bouchat, S., Verdikt, R., Delacourt, N., Vanhulle, C., Van Driessche, B., DARCIS, G., Pasternak, A., Avettand-Fenoel, V., Ledouce, V., Bendoumou, M., Schwartz, C., De Wit, S., Berkhout, B., Gautier, V., Rouzioux, C., Rohr, O., & Van Lint, C. (2017). Identification of a new factor involved in DNA methylation-mediated repression of latent HIV-1. Journal of the International AIDS Society.

DARCIS, G., Bouchat, S., Kula, A., Van Driessche, B., Delacourt, N., Vanhulle, C., Avettand-Fenoel, V., De Wit, S., Rohr, O., Rouzioux, C., & Van Lint, C. (2017). Reactivation capacity by latency-reversing agents ex vivo correlates with the size of the HIV-1 reservoir. AIDS, 31 (2), 181-189. doi:10.1097/QAD.0000000000001290
Peer Reviewed verified by ORBi

DARCIS, G., & Moutschen, M. (2017). Guérir l'infection par le VIH: Un objectif réaliste? Revue Médicale de Liège, 72 (9), 388-392.
Peer reviewed

DARCIS, G., Hayette, M.-P., BONTEMS, S., SAUVAGE, A.-S., MEURIS, C., Van Esbroeck, M., & LEONARD, P. (March 2016). Louse-borne relapsing fever in a refugee from Somalia arriving in Belgium. Journal of Travel Medicine, 23 (3). doi:10.1093/jtm/taw009
Peer Reviewed verified by ORBi

Bouchat, S., Delacourt, N., Kula, A., DARCIS, G., Van Driessche, B., Corazza, F., GATOT, J.-S., Melard, A., Vanhulle, C., Kabeya, K., Pardons, M., Avettand-Fenoel, V., Clumeck, N., De Wit, S., Rohr, O., Rouzioux, C., & Van Lint, C. (2016). Sequential treatment with 5-aza-2'-deoxycytidine and deacetylase inhibitors reactivates HIV-1. EMBO Molecular Medicine. doi:10.15252/emmm.201505557
Peer Reviewed verified by ORBi

DARCIS, G., Coombs, R. W., & Van Lint, C. (2016). Exploring the anatomical HIV reservoirs: Role of the testicular tissue. AIDS, 30 (18), 2891-2893. doi:10.1097/QAD.0000000000001281
Peer Reviewed verified by ORBi

DARCIS, G., Van Driessche, B., & Van Lint, C. (2016). Preclinical shock strategies to reactivate latent HIV-1: An update. Current Opinion in HIV and AIDS, 11 (4), 388-393. doi:10.1097/COH.0000000000000288
Peer reviewed

DARCIS, G., Bouchat, S., Kula, A., Van Driessche, B., Delacourt, N., Vanhulle, C., De Wit, S., Rohr, O., Rouzioux, C., & Van Lint, C. (2016). Reactivation capacity by latency reversing agents ex vivo correlates with the size. Paper presented at 1st EU4HIVCURE symposium in University College Dublin.

DARCIS, G., Bouchat, S., Kula, A., Van Driessche, B., Delacourt, N., Vanhulle, C., De Wit, S., Rohr, O., Rouzioux, C., & Van Lint, C. (2016). Reactivation capacity by latency reversing agents ex vivo correlates with the size of the HIV-1 reservoir. International Journal on Advances in Life Sciences.

SAUVAGE, A.-S., DARCIS, G., & Moutschen, M. (2016). Actualité thérapeutique dans le VIH: Le ténofovir alafénamide. Revue Médicale Suisse, 12 (527), 1367-1369.
Peer Reviewed verified by ORBi

DARCIS, G., Kula, A., Bouchat, S., Fujinaga, K., Corazza, F., Ait-Ammar, A., Delacourt, N., Melard, A., Kabeya, K., Vanhulle, C., Van Driessche, B., GATOT, J.-S., Cherrier, T., Pianowski, L. F., Gama, L., Schwartz, C., Vila, J., Burny, A., Clumeck, N., & Van Lint, C. (2015). An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression. PLoS Pathogens, 11 (7), 1005063. doi:10.1371/journal.ppat.1005063
Peer Reviewed verified by ORBi

Kumar, A.* , DARCIS, G.* , Van Lint, C., & Herbein, G. (2015). Epigenetic control of HIV-1 post integration latency: Implications for therapy. Clinical Epigenetics, 7 (1). doi:10.1186/s13148-015-0137-6
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

DARCIS, G., Kula, A., Bouchat, S., Kabeya, K., Delacourt, N., Vanhulle, C., GATOT, J.-S., VAIRA, D., Burny, A., Clumeck, N., Rohr, O., MOUTSCHEN, M., Corrazza, F., Rouzioux, C., De Wit, S., & Van Lint, C. (2014). Synergistic activation of HIV-1 expression by compounds targeting the positive transcription elongation factor b (P-TEFb) and by inducers of the NF-kB signaling pathway. Paper presented at 20th AIDS international conference, Melbourne, Australia.

DARCIS, G., Kula, A., Bouchat, S., Kabeya, K., Delacourt, N., Vanhulle, C., GATOT, J.-S., VAIRA, D., Burny, A., Herbein, G., Clumeck, N., Rohr, O., MOUTSCHEN, M., Rouzioux, C., De Wit, S., & Van Lint, C. (2013). Synergistic activation of HIV-1 expression by compounds targeting the positive transcription elongation factor b (P-TEFb) and by inducers of the NF-B signaling pathway. Paper presented at 14th European AIDS Conference (EACS), Brussels.

DARCIS, G., Kula, A., Bouchat, S., Kabeya, K., Delacourt, N., Vanhulle, C., GATOT, J.-S., VAIRA, D., Burny, A., Herbein, G., Clumeck, N., Rohr, O., MOUTSCHEN, M., Rouzioux, C., De Wit, S., & Van Lint, C. (2013). Synergistic activation of HIV-1 expression by compounds targeting the positive transcription elongation factor b (P-TEFb) and by inducers of the NF-B signaling pathway. Paper presented at First annual meeting Belgian Society for Virology.

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