  | Arslan, D., Schoumacher, M., Dilly, S., Elmoualij, B., Zorzi, D., Quatresooz, P., Lambert, V., Noël, A., Pirotte, B., & De Tullio, P. (2023). Design, Synthesis, and Evaluation of Novel Pyruvate Dehydrogenase Kinase Inhibitors. Medicinal Chemistry, 19 (3), 276-296. doi:10.2174/1573406418666220819102627  Peer Reviewed verified by ORBi |
Geubelle, P., Gilissen, J., Laschet, C., Dilly, S., Huart, J., Jouret, F., Pirotte, B., & Hanson, J. (13 September 2017). Development of original ligands for SUCNR1 [Poster presentation]. International Symposium on GPCRs and G-proteins, Bonn, Königswinter, Germany. |
 | Arslan, D., Pirotte, B., De Tullio, P., Charif, M. (Other coll.), Dilly, S. (Other coll.), Hansen, S. (Other coll.), LAMBERT, V. (Other coll.), Elmoualij, B. (Other coll.), & Noël, A. (Other coll.). (09 September 2014). AGE-RELATED MACULAR DEGENERATION (AMD): FROM METABOLOMICS APPROACH TO THE INHIBITION OF PDK AS A NEW THERAPEUTIC TARGET [Poster presentation]. XXIII International Symposium on Medicinal Chemistry (EFMC-ISMC 2014), Lisbonne, Portugal. |
  | Dilly, S., Badarau, E., Dufour, F., Nistor, I., Hubert, P., Seutin, V., Wouters, J., & Liégeois, J.-F. (05 June 2014). A PREFERENTIAL FOLDED CONFORMATION OF SOME BIS-(8-ISOPROPYL-ISOQUINOLINIUM) DERIVATIVES EXPLAINS STEREOSELECTIVE REDUCTION BY SODIUM BOROHYDRIDE [Poster presentation]. 28èmes Journées Franco-Belges de Pharmacochimie, Metz, France. |
 | Drapier, T., Goffin, E., Hanson, J., Dilly, S., Francotte, P., Kastrup, J., & Pirotte, B. (June 2014). DESIGN OF HIGH-AFFINITY LIGANDS FOR THE BENZOTHIADIAZINE ALLOSTERIC BINDING SITE OF THE AMPA RECEPTORS [Poster presentation]. 28èmes Journées franco-belges de Pharmacochimie, Metz, France. |
 | Dilly, S., Badarau, E., Dufour, F., Nistor, I., Hubert, P., Seutin, V., Wouters, J., & Liégeois, J.-F. (2014). Structural analysis of some bis-(8-isopropyl-isoquinolinium) derivatives reveals a preferential folded conformation leading to a stereoselective attack by sodium borohydride. Journal of Molecular Structure. doi:10.1016/j.molstruc.2014.06.042 Peer Reviewed verified by ORBi |
Arslan, D., Pirotte, B., De Tullio, P., Charif, M. (Other coll.), Dilly, S. (Other coll.), Hansen, S. (Other coll.), LAMBERT, V. (Other coll.), Elmoualij, B. (Other coll.), & Noël, A. (Other coll.). (June 2014). Inhibition of PDH Kinase as a new therapeutic target for Age-related Macular Degeneration (AMD) [Poster presentation]. 28e Journées franco-belges de Pharmacochimie, Communauté de Metz Métropole, France. |
| Badarau, E.* , Dilly, S.* , Wouters, J., Seutin, V., & Liégeois, J.-F. (2014). Chemical modifications of the N-methyl laudanosine scaffold point to new directions for SK channels exploration. Bioorganic and Medicinal Chemistry Letters, 24, 5616-5620. doi:10.1016/j.bmcl.2014.10.083 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | Liégeois, J.-F., Lespagnard, M., Meneses Salas, E., Mangin, F., Scuvée-Moreau, J., & Dilly, S. (2014). Enhancing a CH-pi interaction to increase the affinity for 5-HT1A receptors. ACS Medicinal Chemistry Letters, 5, 358-362. doi:10.1021/ml4004843 Peer Reviewed verified by ORBi |
| Liégeois, J.-F., Wouters, J., Seutin, V., & Dilly, S. (2014). Bis-(1,2,3,4-tetrahydroisoquinolinium): a chiral scaffold for developing high affinity ligands for SK channels. ChemMedChem, 9, 737-740. doi:10.1002/cmdc.201400028 Peer Reviewed verified by ORBi |
| Liégeois, J.-F., Seutin, V., & Dilly, S. (09 November 2013). Increased affinity of N-Methyl-AG525 stereoisomers for SK2 and SK3 channels [Poster presentation]. 43th Annual Meeting Neuroscience, San Diego, United States. |
| Liégeois, J.-F., Lespagnard, M., Meneses-Salas, E., Mangin, F., & Dilly, S. (July 2013). CHANGING THE ELECTRONIC DENSITY OF THE DISTAL PHENYL RING OF 4-ARYL-1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES TO INFLUENCE THE AFFINITY FOR 5-HT1A RECEPTORS [Poster presentation]. Rencontres Internationales de Chimie Thérapeutique (RICT) 2013, Nice, France. |
 | Arslan, D., Dilly, S., LAMBERT, V., Hansen, S., RAKIC, J.-M., Noël, A., Govaerts, B., Pirotte, B., & De Tullio, P. (06 June 2013). Age-related Macular Degeneration (AMD): from Metabolomics approach to the inhibition of PDH Kinase as a new therapeutic target [Poster presentation]. 27e Journées franco-belges de Pharmacochimie, Lille, France. |
 | Dilly, S., & Liégeois, J.-F. (June 2013). A HYDROGEN BOND INFLUENCES THE 5-HT1A/D4 SELECTIVITY OF WAY-100635 ANALOGUES: AN IN SILICO APPROACH [Poster presentation]. 27èmes Journées franco-belges de Pharmacochimie et 21èmes Conférences européennes du GP2A, Lille, France. |
 | Dilly, S., Philippart, F., Lamy, C., Poncin, S., Snyders, D., Seutin, V., & Liégeois, J.-F. (2013). The interactions of apamin and tetraethylammonium are differentially affected by single mutations in the pore mouth of small conductance calcium-activated potassium (SK) channels. Biochemical Pharmacology, 85, 560-569. doi:10.1016/j.bcp.2012.12.015 Peer Reviewed verified by ORBi |
 | Dilly, S., Mangin, F., Joly, B., Scuvée-Moreau, J., Evans, J., Setola, V., Roth, B., & Liégeois, J.-F. (24 May 2012). PHARMACOMODULATIONS DU WAY-100635 : DE NOUVELLES PISTES DANS LA CONCEPTION D’ANTAGONISTES SÉLECTIFS DES RÉCEPTEURS 5-HT1A [Poster presentation]. 26èmes Journées Franco-Belges de Pharmacochimie 2012, Orléans, France. |
 | Dilly, S., Poncin, S., Lamy, C., Liégeois, J.-F., & Seutin, V. (April 2012). Physiologie, pharmacologie et modélisation de canaux potassiques : zoom sur les canaux SK. MS. Medecine Sciences, 28, 395-402. doi:10.1051/medsci/2012284017 Peer Reviewed verified by ORBi |
 | Dilly, S., Lamy, C., Poncin, S., Seutin, V., Snyders, D., & Liégeois, J.-F. (16 March 2012). Interactions of apamin with pore mutated SK3 channels [Poster presentation]. Belgian Society for Fundamental and Clinical Physiology and Pharmacology, Spring Meeting 2010, Brussels, Belgium. |
 | Mangin, F., Dilly, S., Joly, B., Scuvée-Moreau, J., Evans, J., Setola, V., Roth, B., & Liégeois, J.-F. (2012). Moderate chemical modifications of WAY-100635 improve the selectivity for 5-HT1A versus D4 receptors. Bioorganic and Medicinal Chemistry Letters. doi:10.1016/j.bmcl.2012.05.119 Peer Reviewed verified by ORBi |
 | Liégeois, J.-F., DEVILLE, M., Dilly, S., Lamy, C., Mangin, F., Résimont, M., & Tarazi, F. (2012). New pyridobenzoxazepine derivatives derived from 5-(4-methylpiperazin-1-yl)-8-chloro-pyrido[2,3-b][1,5]benzoxazepine (JL13): chemical synthesis and pharmacological evaluation. Journal of Medicinal Chemistry, 55 (1572), 1582. doi:10.1021/jm2013419 Peer Reviewed verified by ORBi |
 | Badarau, E., Dilly, S., Dufour, F., Poncin, S., Seutin, V., & Liégeois, J.-F. (15 November 2011). Synthesis and radioligand binding studies of bis-(8-isopropylisoquinolinium) derivatives as ligands for apamin-sensitive sites on cloned SK2 and SK3 channels. Bioorganic and Medicinal Chemistry Letters, 21 (22), 6756-6759. doi:10.1016/j.bmcl.2011.09.043 Peer Reviewed verified by ORBi |
 | Dilly, S., Lamy, C., Marrion, N., Liégeois, J.-F., & Seutin, V. (16 August 2011). Ion channel modulators: more diversity than previously thought. Chembiochem: A European Journal of Chemical Biology, 12 (12), 1808-1812. doi:10.1002/cbic.201100236 Peer Reviewed verified by ORBi |
 | Dilly, S., Scuvée-Moreau, J., Wouters, J., & Liégeois, J.-F. (2011). The 5-HT1A agonism potential of substituted-piperazine-ethyl-amide derivatives is conserved in the hexyl homologues: molecular modeling and pharmacological evaluation. Journal of Chemical Information and Modeling, 51 (11), 2961-2966. doi:10.1021/ci200313r Peer Reviewed verified by ORBi |
 | Florence, X., Dilly, S., De Tullio, P., Pirotte, B., & Lebrun, P. (2011). Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process. Bioorganic and Medicinal Chemistry. doi:10.1016/j.bmc.2011.05.040 Peer Reviewed verified by ORBi |
 | Dintilhac, G., Arslan, D., Dilly, S., Danober, L., Botez, I., Lestage, P., Pirotte, B., & De Tullio, P. (2011). New substituted aryl esters and aryl amides of 3,4-dihydro-2H-1,2,4- benzothiadiazine 1,1-dioxides as positive allosteric modulators of AMPA receptors. MedChemComm, 2, 509. doi:10.1039/c1md00069a Peer Reviewed verified by ORBi |
 | Dilly, S., & Liégeois, J.-F. (2011). Interaction of clozapine and its nitrenium ion with rat D2 dopamine receptors: in vitro binding and computational study. Journal of Computer-Aided Molecular Design, 25 (2), 163-169. doi:10.1007/s10822-010-9407-8 Peer Reviewed verified by ORBi |
 | Liégeois, J.-F., & Dilly, S. (16 November 2010). Binding properties of clozapine and related compounds on native D2 dopamine receptors in normal and oxidative medium [Poster presentation]. 40th Annual Meeting Neuroscience, San Diego, United States. |
 | Dilly, S., Lamy, C., Snyders, D., Liégeois, J.-F., & Seutin, V. (16 October 2010). Block of SK channels by the sigma agonist 1,3-di-o-tolyl-guanidine: evidence for a novel site of action for SK blockers [Poster presentation]. Belgian Society for Fundamental and Clinical Physiology and Pharmacology, Autumn Meeting 2010, Brussels, Belgium. |
 | Dilly, S., Lamy, C., Seutin, V., & Liégeois, J.-F. (20 May 2010). Etude du mode de liaison des canaux potassiques de type SK et l’apamine par modélisation moléculaire [Poster presentation]. 24èmes JOURNEES FRANCO-BELGES DE PHARMACOCHIMIE, Bruxelles, Belgium. |
 | Dilly, S., Graulich, A., & Liégeois, J.-F. (January 2010). Molecular modeling study of 4-phenylpiperazine and 4-phenyl-1,2,3,6-tetrahydropyridine derivatives: A new step towards the design of high-affinity 5-HT1A ligands. Bioorganic and Medicinal Chemistry Letters, 20 (2), 1118-1123. doi:10.1016/j.bmcl.2009.12.027 Peer Reviewed verified by ORBi |
 | Dilly, S., Lamy, C., Liégeois, J.-F., & Seutin, V. (2010). Combined experimental and computational approaches to study the action of blockers of small conductance calcium-activated potassium (SK) channels. Acta Physiologica Scandinavica, 199 (supplement 678), 10. |
| Lamy, C., Scuvée-Moreau, J., Dilly, S., Liégeois, J.-F., & Seutin, V. (2010). The sigma agonist 1,3-di-o-tolylguanidine directly blocks SK channels in dopaminergic neurons and in cell lines. European Journal of Pharmacology, 641, 23-28. doi:10.1016/j.ejphar.2010.05.008 Peer Reviewed verified by ORBi |
 | Dilly, S., Graulich, A., & Liégeois, J.-F. (14 May 2009). Conformational analysis of new 5-HT1A ligands by molecular modeling [Paper presentation]. 14th Forum of Pharmaceutical Sciences, Blankenberge, Belgium. |
 | Lamy, C., Scuvée-Moreau, J., Dilly, S., Goodchild, S., Marrion, N., Liégeois, J.-F., & Seutin, V. (17 November 2008). Direct block of SK2 and SK3 current by the sigma agonist 1,3-di-(2-tolyl)guanidine [Poster presentation]. 38th Annual Meeting Neuroscience, Washington, United States. |
 | Kambia, N., Renault, N., Dilly, S., Farce, A., Dine, T., Gressier, B., Luyckx, M., Brunet, C., & Chavatte, P. (October 2008). Molecular modeling of phthalates – PPARs interactions. Journal of Enzyme Inhibition and Medicinal Chemistry, 23 (5), 611-616. doi:10.1080/14756360802205059 Peer Reviewed verified by ORBi |
 | Farce, A., Chugunov, A. O., Logé, C., Sabaouni, A., Yous, S., Dilly, S., Renault, N., Vergoten, G., Efremov, R. G., Lesieur, D., & Chavatte, P. (September 2008). Homology modeling of MT(1) and MT(2) receptors. European Journal of Medicinal Chemistry, 43, 1926-1944. doi:10.1016/j.ejmech.2007.12.001 Peer Reviewed verified by ORBi |
 | Dilly, S., Graulich, A., Chavatte, P., Seutin, V., & Liégeois, J.-F. (30 May 2008). Molecular modelling study of bis-isoquinolinium derivatives as small conductance Ca2+ - activated K+ channel blockers [Poster presentation]. 22èmes journées franco-belges de pharmacochimie, Caen, France. |
 | Graulich, A., Lamy, C., Alleva, L., Dilly, S., Chavatte, P., Wouters, J., Seutin, V., & Liégeois, J.-F. (2008). Bis-tetrahydroisoquinoline derivatives: AG525E1, a new step in the search for non-quaternary non-peptidic small conductance Ca2+-activated K+ channel blockers. Bioorganic and Medicinal Chemistry Letters, 18 (11), 3440-3445. doi:10.1016/j.bmcl.2008.03.069 Peer Reviewed verified by ORBi |
 | Graulich, A., Dilly, S., Farce, A., Scuvée-Moreau, J., Waroux, O., Lamy, C., Chavatte, P., Seutin, V., & Liégeois, J.-F. (18 October 2007). Synthesis and Radioligand Binding Studies of Bis-Isoquinolinium Derivatives as Small Conductance Ca(2+)-Activated K(+) Channel Blockers. Journal of Medicinal Chemistry, 50 (21), 5070-5075. doi:10.1021/jm070412j Peer Reviewed verified by ORBi |
 | Durand, A.-C., Farce, A., Carato, P., Dilly, S., Yous, S., Berthelot, P., & Chavatte, P. (October 2007). Quantitative Structure-Activity Relatioships studies of antioxydant hexahydropyridoindoles and flavonoids derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry, 22 (5), 556-562. doi:10.1080/14756360701425238 Peer Reviewed verified by ORBi |
 | Farce, A., Dilly, S., Sabaouni, A., Yous, S., Berthelot, P., Boutin, J. A., Delagrange, P., Renard, P., & Chavatte, P. (27 March 2007). Three-dimensional quantitative structure-activity relationship of MT3 melatonin binding site ligands: a comparative molecular field analysis. QSAR and Combinatorial Science, 26 (7), 820-827. doi:10.1002/qsar.200630131 Peer Reviewed verified by ORBi |
 | Dilly, S., Farce, A., Yous, S., Berthelot, P., & Chavatte, P. (27 September 2006). Construction d’un modèle du récepteur sérotoninergique 5HT2c [Poster presentation]. 6ème Journée André Verbert - Colloque des doctorants de Lille 2, Lille, France. |
 | Farce, A., Dilly, S., Yous, S., Berthelot, P., & Chavatte, P. (June 2006). Homology modeling of the serotoninergic 5-HT2c receptor. Journal of Enzyme Inhibition and Medicinal Chemistry, 21, 285-292. doi:10.1080/14756360600700608 Peer Reviewed verified by ORBi |
 | Dilly, S., Graulich, A., Farce, A., Seutin, V., Liégeois, J.-F., & Chavatte, P. (December 2005). Identification of a pharmacophore of SKCa channel blockers. Journal of Enzyme Inhibition and Medicinal Chemistry, 20 (6), 517-523. doi:10.1080/14756360500210989 Peer Reviewed verified by ORBi |
 | Dilly, S., Graulich, A., Farce, A., Seutin, V., Liégeois, J.-F., & Chavatte, P. (28 January 2005). Recherche d’un pharmacophore de ligands de canaux SK par Modélisation Moléculaire [Paper presentation]. 12ème Journée Jeunes Chercheurs, Institut Curie, Paris, France. |
 | Hadjaz, F., Besret, S., Martin-Nizard, F., Yous, S., Dilly, S., Lebegue, N., Chavatte, P., Duriez, P., Berthelot, P., & Carato, P. (June 2001). Antioxydant activity of β-carboline derivatives in the LDL oxidation model. European Journal of Medicinal Chemistry, 46, 2575-2585. Peer Reviewed verified by ORBi |