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Flasse Lydie

Département des sciences de la vie

GIGA Cancer - Zebrafish Development and Disease Model

See author's contact details
Main Referenced Co-authors
Peers, Bernard  (15)
Voz, Marianne  (10)
Manfroid, Isabelle  (7)
Pendeville-Samain, Hélène  (6)
Dohet, Manon  (5)
Main Referenced Keywords
Zebrafish (6); Animals (3); TFIP11 (3); Alternative Splicing (2); Gene Expression Regulation, Developmental (2);
Main Referenced Unit & Research Centers
Giga-Development and Stem Cells - ULiège (3)
GIGA Platform Zebrafish Facility & Transgenics - ULiège (1)
GIGA Stem Cells-Zebrafish Development and Disease Model - ULiège (1)
GIGA-AUHG - GIGA Cancer-Human Genetics - ULiège (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (14)
Anatomy (cytology, histology, embryology...) & physiology (4)
Genetics & genetic processes (2)
General & internal medicine (1)

Publications (total 21)

The most downloaded
449 downloads
Flasse, L., Schewin, C., & Grapin-Botton, A. (2021). Pancreas morphogenesis: Branching in and then out. In Cellular Networks in Development. Elsevier. doi:10.1016/bs.ctdb.2020.10.006 https://hdl.handle.net/2268/299845

The most cited

150 citations (OpenAlex)

Soyer, J.* , Flasse, L.* , Raffelsberger, W., Beucher, A., Orvain, C., Peers, B., Ravassard, P., Vermot, J., Voz, M., Mellitzer, G., & Gradwohl, G. (January 2010). Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. Development, 137 (2), 203-12. doi:10.1242/dev.041673 https://hdl.handle.net/2268/73291

Book chapters or contributions to a collective book as author or co-author

Flasse, L., Schewin, C., & Grapin-Botton, A. (2021). Pancreas morphogenesis: Branching in and then out. In Cellular Networks in Development. Elsevier. doi:10.1016/bs.ctdb.2020.10.006
Peer Reviewed verified by ORBi

Articles accepted in reviewed journal

JACQUINET, A., Flasse, L., Dohet, M., Vanhaeren, R., Pendeville-Samain, H., Saunders, C., Lehman, A., Pienkowski, C., Morcel, K., Guerrier, D., Bours, V.* , & Peers, B.*. (2026). Variants in NR6A1 as a cause for congenital renal, vertebral and uterine anomalies. Human Genetics. doi:10.1007/s00439-025-02806-1
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Massoz, L., Bergemann, D., Lavergne, A., Reynders, C., Désiront, C., Goossens, C., Flasse, L., Peers, B., Voz, M., & Manfroid, I. (2024). Negative cell cycle regulation by Calcineurin is necessary for proper beta cell regeneration in zebrafish. eLife. doi:10.7554/elife.88813.1
Peer Reviewed verified by ORBi

Reuter, A.-S., Stern, D., Bernard, A., Goossens, C., Lavergne, A., Flasse, L., Von Berg, V., Manfroid, I., Peers, B., & Voz, M. (14 March 2022). Identification of an evolutionarily conserved domain in Neurod1 favouring enteroendocrine versus goblet cell fate. PLoS Genetics, 18 (3), 1010109. doi:10.1371/journal.pgen.1010109
Peer Reviewed verified by ORBi

Flasse, L., Yennek, S., Cortijo, C., Barandiaran, I. S., Kraus, M. R.-C., & Grapin-Botton, A. (26 May 2020). Apical Restriction of the Planar Cell Polarity Component VANGL in Pancreatic Ducts Is Required to Maintain Epithelial Integrity. Cell Reports, 31 (8), 107677. doi:10.1016/j.celrep.2020.107677
Peer Reviewed verified by ORBi

Lavergne, A.* , Tarifeño-Saldivia, E.* , Pirson, J., Reuter, A.-S., Flasse, L., Manfroid, I., Voz, M.* , & Peers, B.*. (2020). Pancreatic and intestinal endocrine cells in zebrafish share common transcriptomic signatures and regulatory programmes. BMC Biology, 18 (1), 109. doi:10.1186/s12915-020-00840-1
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Dahl-Jensen, S. B., Yennek, S., Flasse, L., Larsen, H. L., Sever, D., Karremore, G., Novak, I., Sneppen, K., & Grapin-Botton, A. (July 2018). Deconstructing the principles of ductal network formation in the pancreas. PLoS Biology, 16 (7), 2002842. doi:10.1371/journal.pbio.2002842
Peer Reviewed verified by ORBi

Ghaye, A., Bergemann, D., Tarifeño Saldivia, E., Flasse, L., Von Berg, V., Peers, B., Voz, M.* , & Manfroid, I.*. (02 September 2015). Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration. BMC Biology, 13, 70. doi:10.1186/s12915-015-0179-4
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Flasse, L., Pirson, J., Stern, D., Von Berg, V., Manfroid, I., Peers, B., & Voz, M. (July 2013). Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish. BMC Biology, 11, 78. doi:10.1186/1741-7007-11-78
Peer Reviewed verified by ORBi

Flasse, L., Stern, D., Pirson, J., Manfroid, I., Peers, B., & Voz, M. (2013). The bHLH transcription factor Ascl1a is essential for the specification of the intestinal secretory cells and mediates Notch signaling in the zebrafish intestine. Developmental Biology, 376 (2), 187-97. doi:10.1016/j.ydbio.2013.01.011
Peer Reviewed verified by ORBi

Binot, A.-C., Manfroid, I., Flasse, L., Winandy, M., Motte, P., Martial, J., Peers, B., & Voz, M. (01 February 2010). Nkx6.1 and nkx6.2 regulate alpha- and beta-cell formation in zebrafish by acting on pancreatic endocrine progenitor cells. Developmental Biology, 340 (2), 397-407. doi:10.1016/j.ydbio.2010.01.025
Peer Reviewed verified by ORBi

Soyer, J.* , Flasse, L.* , Raffelsberger, W., Beucher, A., Orvain, C., Peers, B., Ravassard, P., Vermot, J., Voz, M., Mellitzer, G., & Gradwohl, G. (January 2010). Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. Development, 137 (2), 203-12. doi:10.1242/dev.041673
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

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