Momozawa, Y., Dmitrieva, J. B., Theatre, E., Deffontaine, V., Rahmouni, S., Charloteaux, B., Crins, F., Elansary, M., Gori, A.-S., LECUT, C., Mariman, R., Mni, M., Oury, C., Altukhov, I., Alexeev, D., Aulchenko, Y., Amininejad, L., van der Meulen-de Jong, A. E., van der Woude, C. J., ... Georges, M. (2018). IBD risk loci are enriched in multigenic regulatory modules encompassing causative genes. Nature Communications. doi:10.1038/s41467-018-04365-8 Peer Reviewed verified by ORBi |
Amininejad, L.* , Charloteaux, B.* , Theatre, E., Liefferinckx, C., Dmitrieva, J., Hayard, P., Muls, V., Maisin, J.-M., Schapira, M., Ghislain, J.-M., Closset, P., Talib, M., Abramowicz, M., Momozawa, Y., Deffontaine, V., Crins, F., Mni, M., Karim, L., Cambisano, N., ... Franchimont, D.*. (2018). Analysis of Genes Associated With Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn's Disease. Gastroenterology, 154 (8), 2165-2177. doi:10.1053/j.gastro.2018.02.028 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Huang, H.* , Fang, M.* , Jostins, L.* , Umicevic - Mirkov, M., Boucher, G., Anderson, C. A., Andersen, V., Cleynen, I., Cortes, A., Crins, F., D'Amato, M., Deffontaine, V., Dmitrieva, J. B., DOCAMPO MARTINEZ, E., Elansary, M., Farh, K. K.-H., Franke, A., Gori, A.-S., Goyette, P., ... Barrett, J. C.*. (2017). Fine-mapping inflammatory bowel disease loci to single-variant resolution. Nature, 547 (7662), 173-178. doi:10.1038/nature22969 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Fodil, N., Moradin, N., Leung, V., Olivier, J.-F., Radovanovic, I., Jeyakumar, T., Flores Molina, M., McFarquhar, A., Cayrol, R., Bozec, D., Shoukry, N. H., Kubo, M., Dimitrieva, J., Louis, E., Theatre, E., Dahan, S., Momozawa, Y., Georges, M., Yeretssian, G., & Gros, P. (2017). CCDC88B is required for pathogenesis of inflammatory bowel disease. Nature Communications, 8 (1), 932. doi:10.1038/s41467-017-01381-y Peer Reviewed verified by ORBi |
Cleynen, I., Boucher, G., Jostins, L., Schumm, L. P., Zeissig, S., Ahmad, T., Andersen, V., Andrews, J. M., Annese, V., Brand, S. L., Brant, S. R., Cho, J. H., Daly, M. J., Dubinsky, M., Duerr, R. H., Ferguson, L. R., Franke, A., Gearry, R., Goyette, P., ... Louis, E. (Other coll.). (2016). Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study. The Lancet. doi:10.1016/s0140-6736(15)00465-1 Peer Reviewed verified by ORBi |
Rahmouni, S., MUSUMECI, L., Kuijpers, M. J., Gilio, K., Hego, A., Theatre, E., Senis, Y., Heemskerk, J., Thiry, M., Tautz, L., & Oury, C. (24 June 2015). DUSP3 Phosphatase Deficiency or Inhibition Limits Platelet Activation and Arterial Thrombosis [Paper presentation]. ISTH 2015 Congress, Toronto, Canada. |
Singh, P.* , Dejager, L.* , Amand, M.* , Theatre, E., Vandereyken, M., Zurashvili, T., Singh, M., Mack, M., Timmermans, S., Musumeci, L., Dejardin, E., Mustelin, T., Van Ginderachter, J. A., Moutschen, M., Oury, C., Libert, C., & Rahmouni, S. (15 May 2015). DUSP3 genetic deletion confers M2-like−macrophage-dependent tolerance to septic shock. Journal of Immunology, 194 (10), 4951-62. doi:10.4049/jimmunol.1402431 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Docampo Martínez, E., Fang, M., Dmitrieva, J. B., Theatre, E., Elansary, M., Mariman, R., Gori, A.-S., Mini, M., Crins, F., Coppieters, W., LOUIS, E., & Georges, M. (05 May 2015). Prioritizing likely causative genes in GWAS identified risk loci for immune-mediated inflammatory disorders using cell-type specific eQTL information [Poster presentation]. cold spring harbor laboratory THE BIOLOGY OF GENOMES. |
Musumeci, L., Kuijpers, M., Gilio, K., Hego, A., Theatre, E., Maurissen, L., Vandereyken, M., Diogo, C., LECUT, C., Guilmain, W., Bobkova, E., Eble, J., Dahl, R., Drion, P., Rascon, J., Mostofi, Y., Yuan, H., Sergienko, E., Chung, T., ... Rahmouni, S.*. (17 February 2015). DUSP3 Phosphatase Deficiency or Inhibition Limit Platelet Activation and Arterial Thrombosis. Circulation, 131 (7), 656-68. doi:10.1161/CIRCULATIONAHA.114.010186 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Goyette, P., Boucher, G., Mallon, D., Ellinghaus, E., Jostins, L., Huang, H., Ripke, S., Gusareva, E., Annese, V., Hauser, S. L., Oksenberg, J. R., Thomsen, I., Leslie, S., Theatre, E., Georges, M., Louis, E., Daly, M. J., Van Steen, K., Duerr, R. H., ... Rioux, J. D. (05 January 2015). High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis. Nature Genetics, 47 (2), 172-9. doi:10.1038/ng.3176 Peer Reviewed verified by ORBi |
Cleynen, I., Konings, P., Robberecht, C., Laukens, D., Amininejad, L., Théâtre, E., Machiels, K., Arijs, I., Rutgeerts, P., Louis, E., Franchimont, D., De Vos, M., Van Steen, K., Georges, M., Moreau, Y., Vermeesch, J., & Vermeire, S. (2015). Genome-Wide Copy Number Variation Scan Identifies Complement Component C4 as Novel Susceptibility Gene for Crohn's Disease. Inflammatory Bowel Diseases. doi:10.1097/MIB.0000000000000623 Peer Reviewed verified by ORBi |
Dondelinger, Y., Jouan-Lanhouet, S., Divert, T., Théâtre, E., Bertin, J., Gough, P. J., Giansanti, P., Heck, A. J. R., Dejardin, E., Vandenabeele, P., & Bertrand, M. J. M. (2015). NF-kappaB-Independent Role of IKKalpha/IKKbeta in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling. Molecular Cell. doi:10.1016/j.molcel.2015.07.032 Peer Reviewed verified by ORBi |
Mariman, R., Coppieters, W., Elansary, M., Karim, L., Crins, F., Mni, M., Gori, A.-S., Aoun, N., Docampo Martínez, E., Dmitrieva, J. B., Fang, M., Theatre, E., Eppe, G., & Georges, M. (24 April 2014). Identification of molecular components of the host-microbiota-connectome by using "Omics Approaches" [Poster presentation]. BeMGI. |
Docampo Martínez, E., Theatre, E., Dmitrieva, J. B., Elansary, M., Mariman, R., Mni, M., Crins, F., Gori, A.-S., Fang, M., LOUIS, E., & Georges, M. (24 April 2014). Identifying Inflammatory Bowel Disease causative genes through trans-eQTLs mapping within GWAS loci [Poster presentation]. BeMGI. |
Gori, A.-S., LECUT, C., Theatre, E., Momozawa, Y., Docampo Martínez, E., Mariman, R., Dmitrieva, J. B., Elansary, M., Charloteaux, B., Defontaine, V., Mni, M., Crins, F., LOUIS, E., Georges, M., & Oury, C. (24 April 2014). Combined use of GWAS and eQTL information to identify genes controlling platelet biology [Poster presentation]. BeMGI. doi:10.13140/RG.2.1.4044.9763 |
Van Lishout, F., Mahachie John, J., Gusareva, E., Urrea, V., Cleynen, I., Theatre, E., CHARLOTEAUX, B., Calle, M. L., Wehenkel, L., & Van Steen, K. (24 April 2013). An efficient algorithm to perform multiple testing in epistasis screening. BMC Bioinformatics, 14, 138. doi:10.1186/1471-2105-14-138 Peer Reviewed verified by ORBi |
Kasperaviciute, D., Catarino, C. B., Matarin, M., Leu, C., Novy, J., Tostevin, A., Leal, B., Hessel, E. V. S., Hallmann, K., Hildebrand, M. S., Dahl, H.-H. M., Ryten, M., Trabzuni, D., Ramasamy, A., Alhusaini, S., Doherty, C. P., Dorn, T., Hansen, J., Kramer, G., ... Sisodiya, S. M. (2013). Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A. Brain: a Journal of Neurology, 136 (Pt 10), 3140-50. doi:10.1093/brain/awt233 Peer Reviewed verified by ORBi |
Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., McGovern, D. P., Hui, K. Y., Lee, J. C., Schumm, L. P., Sharma, Y., Anderson, C. A., Essers, J., Mitrovic, M., Ning, K., Cleynen, I., Theatre, E., Spain, S. L., Raychaudhuri, S., Goyette, P., Wei, Z., ... Cho, J. H. (October 2012). Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature, 491 (7422), 119-24. doi:10.1038/nature11582 Peer Reviewed verified by ORBi |
Theatre, E., Frederix, K., Guilmain, W., Delierneux, C., Lecut, C., Bettendorff, L., BOURS, V., & Oury, C. (August 2012). Overexpression of CD39 in mouse airways promotes bacteria induced inflammation. Journal of Immunology, 189 (4), 1966-1974. doi:10.4049/jimmunol.1102600 Peer Reviewed verified by ORBi |
Van Lishout, F., Cattaert, T., Mahachie John, J., Gusareva, E., Urrea, V., Cleynen, I., Theatre, E., Charloteaux, B., Kvasz, A., Calle, M. L., Wehenkel, L., & Van Steen, K. (13 December 2011). An Efficient Algorithm to Perform Multiple Testing in Epistasis Screening [Paper presentation]. Benelux Bioinformatics Conference 2011, Luxembourg, Luxembourg. |
Theatre, E., Bours, V., & Oury, C. (2009). A P2X Ion Channel-triggered NF-{kappa}B Pathway Enhances TNF-{alpha}-induced IL-8 Expression in Airway Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology. doi:10.1165/rcmb.2008-0452OC Peer Reviewed verified by ORBi |
Ortis, F., Pirot, P., Naamane, N., Kreins, A. Y., Rasschaert, J., Moore, F., Theatre, E., Verhaeghe, C., Magnusson, N. E., Chariot, A., Orntoft, T. F., & Eizirik, D. L. (July 2008). Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells. Diabetologia, 51, 1213-1225. doi:10.1007/s00125-008-0999-7 Peer Reviewed verified by ORBi |
Reenaers, C., Franchimont, N., Oury, C., Belaiche, J., Malaise, M., Bours, V., Theatre, E., Delvenne, P., & Louis, E. (2008). Sensitivity of intestinal fibroblasts to TNF-related apoptosis-inducing ligand-mediated apoptosis in Crohn's disease. Scandinavian Journal of Gastroenterology, 43, 1334-1345. doi:10.1080/00365520802200010 Peer Reviewed verified by ORBi |
Theatre, E., Bours, V., & Oury, C. (2008). Airway P2X ion channels mediate IL-8 expression through CaMKII-dependent NF-kappaB activation. Purinergic Signalling. Peer reviewed |
Theatre, E., de Leval, L., Bettendorff, L., Bours, V., & Oury, C. (2008). Overexpression of airway CD39 in transgenic mice enhances lipopolysaccharide-induced inflammation. Purinergic Signalling, 4, 113. Peer reviewed |
Dideberg, V., Theatre, E., Farnir, F., Vermeire, S., Rutgeerts, P., De Vos, M., Belaiche, J., Franchimont, D., Van Gossum, A., Louis, E., & Bours, V. (May 2007). The TNF/ADAM 17 system: implication of an ADAM 17 haplotype in the clinical response to infliximab in Crohn's disease. European Journal of Clinical Investigation, 37 (Suppl. 1), 79. Peer Reviewed verified by ORBi |
Dideberg, V., Theatre, E., Farnir, F., Vermeire, S., Rutgeerts, P., Vos, M. D., Belaiche, J., Franchimont, D., Gossum, A. V., Louis, E., & Bours, V. (October 2006). The Tnf/Adam 17 System: Implication of an Adam 17 Haplotype in the Clinical Response to Infliximab in Crohn's Disease. Pharmacogenetics and Genomics, 16 (10), 727-734. doi:10.1097/01.fpc.0000230117.26581.a4 Peer Reviewed verified by ORBi |