Article (Scientific journals)
Manifestaciones cardiovasculares en el SIDA
Valdes, E. F.; Rostello, E.; Villanueva, H. R. et al.
1996In Prensa Medica Argentina, 83, p. 152-156
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Keywords :
hiv, aids, cardiomyopathy, ventricular dysfonction, echocardiography, arrythmias
Abstract :
[en] Cardiovascular complications in acquired immunodeficiency syndrome. AIDS miocardiopathy has been described since 1983. Physiopathologic events leading to AIDS myocardiopathy are largely unknown: viral miocardiopathy, cytokines induced lesions, nutritional status, microvascular and ischemic miocadiopathy have been suspected. We describe a consecutive series of 50 patients (43 males, 7 women) with HIV infection and severe immunodepression (CD4<200/ml) that had clinical, ECG and echocardiographic evaluation. There were 24 drug addicted patients, 17 homosexual patients, and 10 heterosexuals. Some of these patients had the following opportunistic infections: tuberculosis (n=20), Pneumocystis carinii (n=9), Criptocococis (n=9), oropharyngeal candidosis (n=5), toxoplasmosis (n=5), histoplasmosis (n=1) and Kaposi’s sarcoma (n=2). After clinical evaluation 15/50 patients had some kind of cardiovascular complication: 6 patients had congestive heart failure, 5 patients presented with pericardial effusion, one patient has a reversible cardiac arrest, and one patient had pulmonary valvular endocarditis. After Doppler echocardiographic evaluation (according to the American echocardiography association), we found 20 patients with left ventricular diastolic dysfunction, 9 patients with right ventricular diastolic dysfunction and 6 patients with left ventricular systolic dysfunction. In conclusion, our series found left diastolic dysfunction in nearly 40 % of cases and cardiavasular events (pericarditis, heart congestive failure, arrhythmias) in 26% of cases. Cardiovascular complications have prognostic implications in AIDS and shoul be early detected. Further pathological and immunohistochemical studies are needed to clarify the phyiopathological etiologies in AIDS miocardiopathy.
Disciplines :
General & internal medicine
Author, co-author :
Valdes, E. F.;  Hospital Rivadavia, Buenos Aires
Rostello, E.
Villanueva, H. R.
Miguel, M.
VALDES SOCIN, Hernan Gonzalo  ;  Hospital de Clinicas Jose de San Martin, Buenos Aires > V Catedra de Medicina Interna
Bernarbo, J.
Tagtachian, J.
Language :
English
Title :
Manifestaciones cardiovasculares en el SIDA
Alternative titles :
[en] Cardiovascular complications in AIDS
Publication date :
1996
Journal title :
Prensa Medica Argentina
ISSN :
0032-745X
Publisher :
Prensa Medica Argentina, Buenos Aires, Argentina
Volume :
83
Pages :
152-156
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 25 July 2011

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